{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Medication+Reaction&page=2",
    "query": {
      "condition": "Medication Reaction",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Medication+Reaction&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T05:33:23.973Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04765137",
      "title": "Evaluate the Effect of Atorvastatin on Cerebrovascular Reactivity in Mild Cognitive Impairment (MCI)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Mild Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "Atorvastatin Oral Tablet",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "60 Years to 95 Years"
      },
      "enrollment_count": 20,
      "start_date": "2021-05-21",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-13",
      "last_synced_at": "2026-07-23T05:33:23.973Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04765137"
    },
    {
      "nct_id": "NCT01000987",
      "title": "Effect of Varenicline on Fixed-Dose Alcohol Administration in Participants With Alcohol Use Disorders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Alcohol Reactivity"
      ],
      "interventions": [
        {
          "name": "varenicline",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 44,
      "start_date": "2009-10",
      "completion_date": "2016-11",
      "has_results": true,
      "last_update_posted_date": "2018-02-19",
      "last_synced_at": "2026-07-23T05:33:23.973Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01000987"
    },
    {
      "nct_id": "NCT06264752",
      "title": "Multi-hospital Electronic Decision Support for Drug-associated Acute Kidney Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Kidney Injury"
      ],
      "interventions": [
        {
          "name": "Level A",
          "type": "OTHER"
        },
        {
          "name": "Level B",
          "type": "OTHER"
        },
        {
          "name": "Passive Alert",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 698,
      "start_date": "2024-02-15",
      "completion_date": "2025-07-15",
      "has_results": false,
      "last_update_posted_date": "2025-09-12",
      "last_synced_at": "2026-07-23T05:33:23.973Z",
      "location_count": 8,
      "location_summary": "Altoona, Pennsylvania • Farrell, Pennsylvania • McKeesport, Pennsylvania + 3 more",
      "locations": [
        {
          "city": "Altoona",
          "state": "Pennsylvania"
        },
        {
          "city": "Farrell",
          "state": "Pennsylvania"
        },
        {
          "city": "McKeesport",
          "state": "Pennsylvania"
        },
        {
          "city": "New Castle",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06264752"
    },
    {
      "nct_id": "NCT02188134",
      "title": "Quantifying the Attentive Behaviors of Older Adults During Over-the-counter Drug Selection",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Older Adults (65 Years and Older)"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Michigan State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 82,
      "start_date": "2014-10",
      "completion_date": "2015-04",
      "has_results": false,
      "last_update_posted_date": "2015-04-07",
      "last_synced_at": "2026-07-23T05:33:23.973Z",
      "location_count": 1,
      "location_summary": "East Lansing, Michigan",
      "locations": [
        {
          "city": "East Lansing",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02188134"
    },
    {
      "nct_id": "NCT02738047",
      "title": "Reduction of Adverse Drug Events and Readmissions",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pharmacogenomic Testing for Medication Management"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "ClinLogic LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "25 Years and older"
      },
      "enrollment_count": 280000,
      "start_date": "2019-03-15",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2024-02-07",
      "last_synced_at": "2026-07-23T05:33:23.973Z",
      "location_count": 1,
      "location_summary": "York, Pennsylvania",
      "locations": [
        {
          "city": "York",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02738047"
    },
    {
      "nct_id": "NCT00075101",
      "title": "Sleep, Fatigue, and Dexamethosone in Children With Leukemia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Leukemia"
      ],
      "interventions": [
        {
          "name": "Dexamethosone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute of Nursing Research (NINR)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "5 Years to 21 Years"
      },
      "enrollment_count": 134,
      "start_date": "2000-09",
      "completion_date": "2006-09",
      "has_results": false,
      "last_update_posted_date": "2008-08-18",
      "last_synced_at": "2026-07-23T05:33:23.973Z",
      "location_count": 1,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00075101"
    },
    {
      "nct_id": "NCT03468309",
      "title": "Medication Optimization Using Pharmacogenetic Testing and the G-DIG to Reduce Polypharmacy in a Mental Health Population",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pharmacogenetic Testing"
      ],
      "interventions": [
        {
          "name": "Genecept Assay and G-DIG decision tool",
          "type": "GENETIC"
        }
      ],
      "intervention_types": [
        "GENETIC"
      ],
      "sponsor": "Seattle Institute for Biomedical and Clinical Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 53,
      "start_date": "2018-01-01",
      "completion_date": "2024-04-17",
      "has_results": true,
      "last_update_posted_date": "2024-04-23",
      "last_synced_at": "2026-07-23T05:33:23.973Z",
      "location_count": 1,
      "location_summary": "Tacoma, Washington",
      "locations": [
        {
          "city": "Tacoma",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03468309"
    },
    {
      "nct_id": "NCT06107829",
      "title": "Valbenazine Treatment of Tardive Dyskinesia in Adults With Intellectual/Developmental Disabilities",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Tardive Dyskinesia",
        "Intellectual Disability",
        "Developmental Disabilities"
      ],
      "interventions": [
        {
          "name": "Valbenazine Oral Capsule",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Stephen Ruedrich",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 0,
      "start_date": "2025-01",
      "completion_date": "2027-02",
      "has_results": false,
      "last_update_posted_date": "2024-10-24",
      "last_synced_at": "2026-07-23T05:33:23.973Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06107829"
    },
    {
      "nct_id": "NCT04284553",
      "title": "Optimizing Electronic Health Record Prompts With Behavioral Economics to Improve Prescribing for Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aging",
        "Benzodiazepine Sedative Adverse Reaction",
        "Anticholinergic Adverse Reaction",
        "Adverse Drug Event"
      ],
      "interventions": [
        {
          "name": "Order Entry",
          "type": "OTHER"
        },
        {
          "name": "Open Encounter",
          "type": "OTHER"
        },
        {
          "name": "Follow-up booster Alert",
          "type": "OTHER"
        },
        {
          "name": "Cold State outreach",
          "type": "OTHER"
        },
        {
          "name": "Simplified",
          "type": "OTHER"
        },
        {
          "name": "Sign-off alert",
          "type": "OTHER"
        },
        {
          "name": "Pre-commitment",
          "type": "OTHER"
        },
        {
          "name": "Different Risks",
          "type": "OTHER"
        },
        {
          "name": "Standard Epic Basic Alert",
          "type": "OTHER"
        },
        {
          "name": "Enhanced Alert",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 216,
      "start_date": "2020-10-13",
      "completion_date": "2022-08-31",
      "has_results": true,
      "last_update_posted_date": "2024-11-07",
      "last_synced_at": "2026-07-23T05:33:23.973Z",
      "location_count": 1,
      "location_summary": "Braintree, Massachusetts",
      "locations": [
        {
          "city": "Braintree",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04284553"
    },
    {
      "nct_id": "NCT01826266",
      "title": "Effects of a Double-Blind, Single Dose of PER977 Administered Alone, and Following a Single Dose of Edoxaban",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Anticoagulant Reversal",
        "Reversal of Edoxaban Induced Anticoagulation"
      ],
      "interventions": [
        {
          "name": "PER977, Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 83,
      "start_date": "2013-07",
      "completion_date": "2013-12",
      "has_results": false,
      "last_update_posted_date": "2020-05-28",
      "last_synced_at": "2026-07-23T05:33:23.973Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01826266"
    }
  ]
}