{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Menopausal+Symptoms&page=2",
    "query": {
      "condition": "Menopausal Symptoms",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Menopausal+Symptoms&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T03:07:59.056Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01178892",
      "title": "MsFLASH-02: Interventions for Relief of Menopausal Symptoms: A 3-by-2 Factorial Design Examining Yoga, Exercise, and Omega-3 Supplementation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hot Flashes",
        "Menopause",
        "Vasomotor Symptoms"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Omega-3",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Yoga",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual Activity",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "BEHAVIORAL"
      ],
      "sponsor": "Fred Hutchinson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "62 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 62 Years · Female only"
      },
      "enrollment_count": 355,
      "start_date": "2010-11",
      "completion_date": "2012-05",
      "has_results": false,
      "last_update_posted_date": "2014-08-22",
      "last_synced_at": "2026-05-22T03:07:59.056Z",
      "location_count": 3,
      "location_summary": "Oakland, California • Indianapolis, Indiana • Seattle, Washington",
      "locations": [
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01178892"
    },
    {
      "nct_id": "NCT00283192",
      "title": "Flushes and Sertraline Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Menopause-Hot Flashes"
      ],
      "interventions": [
        {
          "name": "Sertraline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 60 Years · Female only"
      },
      "enrollment_count": 100,
      "start_date": "2003-07",
      "completion_date": "2006-01",
      "has_results": false,
      "last_update_posted_date": "2006-08-04",
      "last_synced_at": "2026-05-22T03:07:59.056Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00283192"
    },
    {
      "nct_id": "NCT01793948",
      "title": "Metformin Hydrochloride vs. Placebo in Overweight or Obese Patients at Elevated Risk for Breast Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Breast Cancer",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "metformin hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "OTHER"
        },
        {
          "name": "laboratory biomarker analysis",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Anna Maria Storniolo",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 75 Years · Female only"
      },
      "enrollment_count": 24,
      "start_date": "2013-04-16",
      "completion_date": "2018-01-09",
      "has_results": false,
      "last_update_posted_date": "2018-03-30",
      "last_synced_at": "2026-05-22T03:07:59.056Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01793948"
    },
    {
      "nct_id": "NCT01050101",
      "title": "The Effects of Fiber on Appetite and Digestion Hormones",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Psychological Phenomena and Processes",
        "Nutrition Physiological Phenomena"
      ],
      "interventions": [
        {
          "name": "No fiber",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Low GI high fiber viscous meal",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Low GI high fiber non-viscous",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Clinical Nutrition Research Center, Illinois Institute of Technology",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 22,
      "start_date": "2008-08-01",
      "completion_date": "2018-12-19",
      "has_results": false,
      "last_update_posted_date": "2021-01-27",
      "last_synced_at": "2026-05-22T03:07:59.056Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01050101"
    },
    {
      "nct_id": "NCT07526948",
      "title": "Vaginal Estradiol vs Moisturizer to Improve Postmenopausal Vaginal Aging Symptoms and the Microbiome in Women Living With HIV",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Menopausal Complaints",
        "Vaginal Atrophy",
        "Genitourinary Symptoms",
        "HIV (Human Immunodeficiency Virus)",
        "Menopause Related Conditions",
        "Vaginitis",
        "Perimenopause"
      ],
      "interventions": [
        {
          "name": "Vaginal estradiol tablets",
          "type": "DRUG"
        },
        {
          "name": "Vaginal moisturizer",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Albert Einstein College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 70 Years · Female only"
      },
      "enrollment_count": 62,
      "start_date": "2026-06-01",
      "completion_date": "2031-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-04-14",
      "last_synced_at": "2026-05-22T03:07:59.056Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07526948"
    },
    {
      "nct_id": "NCT05715372",
      "title": "Genetic Evaluation and Modification of Lifestyles to Improve Female Life Expectancy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Menopause Syndrome",
        "Inflammation",
        "Inflammatory Response",
        "Aging",
        "Menopause",
        "Telomere Shortening",
        "Stress Oxidative"
      ],
      "interventions": [
        {
          "name": "Mediterranean diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "AHA walking program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mindfulness-based stress reduction",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Unstructured Mediterranean diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Unstructured walking program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Unstructured stress reduction",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 60 Years · Female only"
      },
      "enrollment_count": 5,
      "start_date": "2021-06-22",
      "completion_date": "2021-06-22",
      "has_results": false,
      "last_update_posted_date": "2023-02-13",
      "last_synced_at": "2026-05-22T03:07:59.056Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05715372"
    },
    {
      "nct_id": "NCT02092844",
      "title": "Cognitive Behavioral Therapy for Insomnia and Nocturnal Hot Flashes in Menopause",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Menopause",
        "Insomnia",
        "Hot Flashes"
      ],
      "interventions": [
        {
          "name": "CBT for Menopausal Insomnia (CBTMI)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "The University of Texas Medical Branch, Galveston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 65 Years · Female only"
      },
      "enrollment_count": 40,
      "start_date": "2015-01",
      "completion_date": "2016-11",
      "has_results": false,
      "last_update_posted_date": "2017-05-12",
      "last_synced_at": "2026-05-22T03:07:59.056Z",
      "location_count": 1,
      "location_summary": "Galveston, Texas",
      "locations": [
        {
          "city": "Galveston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02092844"
    },
    {
      "nct_id": "NCT03150407",
      "title": "Use of J3 Bioscience Lubricating Intravaginal Ring VR101 to Relieve the Symptoms of Vaginal Dryness",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Menopause Related Conditions",
        "Postmenopausal Symptoms"
      ],
      "interventions": [
        {
          "name": "VR101 Device (Efficacy)",
          "type": "DEVICE"
        },
        {
          "name": "Sham Control Ring",
          "type": "OTHER"
        },
        {
          "name": "VR101 Device (Safety)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "J3 Bioscience, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "35 Years and older · Female only"
      },
      "enrollment_count": 72,
      "start_date": "2017-05-01",
      "completion_date": "2017-11-30",
      "has_results": true,
      "last_update_posted_date": "2022-11-07",
      "last_synced_at": "2026-05-22T03:07:59.056Z",
      "location_count": 2,
      "location_summary": "Meridian, Idaho • West Jordan, Utah",
      "locations": [
        {
          "city": "Meridian",
          "state": "Idaho"
        },
        {
          "city": "West Jordan",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03150407"
    },
    {
      "nct_id": "NCT05617287",
      "title": "An Exploratory Investigation of Dietary Supplementation and the Effect on Common Symptoms of Perimenopause and Menopause",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Menopause",
        "Menopause Related Conditions",
        "Perimenopausal Disorder"
      ],
      "interventions": [
        {
          "name": "Semaine Menopause Supplement",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Semaine Health",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "57 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 57 Years · Female only"
      },
      "enrollment_count": 42,
      "start_date": "2022-09-03",
      "completion_date": "2023-01-01",
      "has_results": false,
      "last_update_posted_date": "2023-04-13",
      "last_synced_at": "2026-05-22T03:07:59.056Z",
      "location_count": 1,
      "location_summary": "Santa Monica, California",
      "locations": [
        {
          "city": "Santa Monica",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05617287"
    },
    {
      "nct_id": "NCT05570721",
      "title": "Depression, Aging, Stress and Heart Health Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Menopause",
        "Depression",
        "Heart Disease in Women",
        "Stress"
      ],
      "interventions": [
        {
          "name": "Trier Social Stress Test",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "44 Years",
        "maximum_age": "55 Years",
        "sex": "FEMALE",
        "summary": "44 Years to 55 Years · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2022-11-16",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-12-22",
      "last_synced_at": "2026-05-22T03:07:59.056Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05570721"
    }
  ]
}