{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Menopause%2C+Premature&page=2",
    "query": {
      "condition": "Menopause, Premature",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Menopause%2C+Premature&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T09:22:09.148Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04439370",
      "title": "Autonomic Regulation of Blood Pressure in Premature and Early Menopausal Women",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hypertension",
        "Menopause, Premature",
        "Menopause",
        "Blood Pressure"
      ],
      "interventions": [
        {
          "name": "Microneurography to measure muscle sympathetic nerve activity (MSNA)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Baroreflex sensitivity testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Sympathoexcitatory Maneuvers",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Blood tests",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "70 Years",
        "sex": "FEMALE",
        "summary": "35 Years to 70 Years · Female only"
      },
      "enrollment_count": 160,
      "start_date": "2019-10-01",
      "completion_date": "2026-12-30",
      "has_results": false,
      "last_update_posted_date": "2026-01-08",
      "last_synced_at": "2026-06-10T09:22:09.148Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04439370"
    },
    {
      "nct_id": "NCT05567198",
      "title": "Gonadotropin-releasing Hormone Agonist (GnRHa) in Ovarian Preservation in SLE Subjects Receiving Cyclophosphamide as Determined by Questionnaires",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Systemic Lupus Erythematosus (Sle)",
        "Primary Ovarian Insufficiency (Poi)"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "120 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 120 Years · Female only"
      },
      "enrollment_count": 100,
      "start_date": "2023-03-03",
      "completion_date": "2027-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-03",
      "last_synced_at": "2026-06-10T09:22:09.148Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05567198"
    },
    {
      "nct_id": "NCT01141972",
      "title": "The Role of Vitamin D in Menopause: Relationship to Menopausal Symptoms in Body Composition",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Hot Flushes",
        "Menopause, Premature",
        "Obesity",
        "Vitamin D Deficiency"
      ],
      "interventions": [
        {
          "name": "Vitamin D",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "Kaiser Permanente",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 60 Years · Female only"
      },
      "enrollment_count": 23,
      "start_date": "2010-09",
      "completion_date": "2012-02",
      "has_results": false,
      "last_update_posted_date": "2013-05-30",
      "last_synced_at": "2026-06-10T09:22:09.148Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01141972"
    },
    {
      "nct_id": "NCT01662466",
      "title": "Effect of Testosterone Treatment on Embryo Quality",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Primary Ovarian Insufficiency",
        "Female Infertility Due to Diminished Ovarian Reserve"
      ],
      "interventions": [
        {
          "name": "Testosterone cream (0.5mg per gram)",
          "type": "DRUG"
        },
        {
          "name": "DHEA",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Center for Human Reproduction",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "38 Years",
        "maximum_age": "44 Years",
        "sex": "FEMALE",
        "summary": "38 Years to 44 Years · Female only"
      },
      "enrollment_count": 180,
      "start_date": "2012-07-01",
      "completion_date": "2022-12-31",
      "has_results": false,
      "last_update_posted_date": "2020-11-12",
      "last_synced_at": "2026-06-10T09:22:09.148Z",
      "location_count": 2,
      "location_summary": "New York, New York • Rochester, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01662466"
    },
    {
      "nct_id": "NCT01023178",
      "title": "Comparison of Transdermal and Oral Estrogens in Adolescent Girls With Ovarian Failure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ovarian Failure, Premature"
      ],
      "interventions": [
        {
          "name": "17beta Estradiol",
          "type": "DRUG"
        },
        {
          "name": "Conjugated estrogens",
          "type": "DRUG"
        },
        {
          "name": "17Beta Estradiol - transdermal",
          "type": "DRUG"
        },
        {
          "name": "Progesterone, micronized",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "18 Years",
        "sex": "FEMALE",
        "summary": "12 Years to 18 Years · Female only"
      },
      "enrollment_count": 20,
      "start_date": "2007-02",
      "completion_date": "2013-06",
      "has_results": true,
      "last_update_posted_date": "2017-01-20",
      "last_synced_at": "2026-06-10T09:22:09.148Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01023178"
    },
    {
      "nct_id": "NCT00370019",
      "title": "Effects of an Estrogen Replacement Therapy Skin Patch on Ovulation in Women With Premature Ovarian Failure",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Premature Ovarian Failure"
      ],
      "interventions": [
        {
          "name": "Estradiol/Medroxyprogesterone acetate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2006-08-25",
      "completion_date": "2011-12-12",
      "has_results": false,
      "last_update_posted_date": "2017-07-02",
      "last_synced_at": "2026-06-10T09:22:09.148Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00370019"
    },
    {
      "nct_id": "NCT06866119",
      "title": "Effects of Estrogen on Heart Health in Women With Primary Ovarian Insufficiency",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Primary Ovarian Insufficiency",
        "Premature Menopause",
        "Metabolic Complications",
        "Endothelial Function (FMD)",
        "Estrogen Replacement Therapy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "30 Years to 40 Years · Female only"
      },
      "enrollment_count": 45,
      "start_date": "2026-03-01",
      "completion_date": "2026-06",
      "has_results": false,
      "last_update_posted_date": "2026-01-07",
      "last_synced_at": "2026-06-10T09:22:09.148Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06866119"
    },
    {
      "nct_id": "NCT02181595",
      "title": "Deep Reading as a Contemplative Practice for Women With Primary Ovarian Insufficiency",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Ovarian Insufficiency"
      ],
      "interventions": [
        {
          "name": "Group reading and discussion",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 6,
      "start_date": "2014-07-02",
      "completion_date": "2018-03-20",
      "has_results": false,
      "last_update_posted_date": "2019-12-16",
      "last_synced_at": "2026-06-10T09:22:09.148Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02181595"
    },
    {
      "nct_id": "NCT04948658",
      "title": "Gonadal Tissue Freezing for Fertility Preservation in Individuals at Risk for Ovarian Dysfunction, Premature Ovarian Insufficiency and Clinically Indicated Gonadectomy",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Turner Syndrome",
        "Post-menarcheal Adolescents",
        "Ovarian Disfunction",
        "Galactosemia",
        "Variations in Sex Characteristics",
        "Differences in Sex Development"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "2 Years to 35 Years"
      },
      "enrollment_count": 200,
      "start_date": "2021-09-13",
      "completion_date": "2030-07-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-01",
      "last_synced_at": "2026-06-10T09:22:09.148Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04948658"
    },
    {
      "nct_id": "NCT00471731",
      "title": "Dry Eye in Women With Turner Syndrome and Women With Premature Ovarian Failure",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Turner Syndrome",
        "Ovarian Failure, Premature",
        "Sex Chromosome Aberrations",
        "Menopause",
        "Perimenopause"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Eye Institute (NEI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 72,
      "start_date": "2007-05-07",
      "completion_date": "2014-11-13",
      "has_results": false,
      "last_update_posted_date": "2018-02-14",
      "last_synced_at": "2026-06-10T09:22:09.148Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00471731"
    }
  ]
}