{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Menopause+Hot+Flashes&page=2",
    "query": {
      "condition": "Menopause Hot Flashes",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Menopause+Hot+Flashes&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T06:23:48.449Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01300078",
      "title": "A Clinical Trial Assessing Safety of MF101 for Hot Flushes",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Hot Flashes"
      ],
      "interventions": [
        {
          "name": "MF101",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Bionovo",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 65 Years · Female only"
      },
      "enrollment_count": 40,
      "start_date": "2011-03",
      "completion_date": "2011-06",
      "has_results": false,
      "last_update_posted_date": "2011-06-02",
      "last_synced_at": "2026-06-26T06:23:48.449Z",
      "location_count": 4,
      "location_summary": "Berkeley, California • Lincoln, California • Sacramento, California + 1 more",
      "locations": [
        {
          "city": "Berkeley",
          "state": "California"
        },
        {
          "city": "Lincoln",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01300078"
    },
    {
      "nct_id": "NCT04209543",
      "title": "Estetrol for the Treatment of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women (E4Comfort Study I)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Vasomotor Symptoms",
        "Menopausal Symptoms"
      ],
      "interventions": [
        {
          "name": "Estetrol",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Progesterone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Estetra",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 65 Years · Female only"
      },
      "enrollment_count": 1570,
      "start_date": "2019-12-30",
      "completion_date": "2024-02-08",
      "has_results": false,
      "last_update_posted_date": "2025-01-29",
      "last_synced_at": "2026-06-26T06:23:48.449Z",
      "location_count": 65,
      "location_summary": "Birmingham, Alabama • Mesa, Arizona • Phoenix, Arizona + 52 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04209543"
    },
    {
      "nct_id": "NCT01116401",
      "title": "Impact of Hot Flashes on Sleep and Mood Disturbance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Menopause",
        "Depression",
        "Hot Flashes"
      ],
      "interventions": [
        {
          "name": "leuprolide",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 29,
      "start_date": "2009-11-03",
      "completion_date": "2012-01-04",
      "has_results": true,
      "last_update_posted_date": "2018-01-23",
      "last_synced_at": "2026-06-26T06:23:48.449Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01116401"
    },
    {
      "nct_id": "NCT01126801",
      "title": "Effects of Estrogen and Hot Flashes on Mood in Postmenopausal Women",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Menopausal Depression"
      ],
      "interventions": [
        {
          "name": "Estradiol",
          "type": "DRUG"
        },
        {
          "name": "Placebo control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "40 Years and older · Female only"
      },
      "enrollment_count": 2,
      "start_date": "2010-05",
      "completion_date": "2011-02",
      "has_results": true,
      "last_update_posted_date": "2017-10-20",
      "last_synced_at": "2026-06-26T06:23:48.449Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01126801"
    },
    {
      "nct_id": "NCT04003142",
      "title": "A Study to Find Out if Fezolinetant Helps Reduce Moderate to Severe Hot Flashes in Women Going Through Menopause - 2",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Hot Flashes"
      ],
      "interventions": [
        {
          "name": "Fezolinetant",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Astellas Pharma Global Development, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 65 Years · Female only"
      },
      "enrollment_count": 501,
      "start_date": "2019-07-10",
      "completion_date": "2021-04-23",
      "has_results": true,
      "last_update_posted_date": "2024-11-05",
      "last_synced_at": "2026-06-26T06:23:48.449Z",
      "location_count": 65,
      "location_summary": "Mesa, Arizona • Phoenix, Arizona • Tucson, Arizona + 53 more",
      "locations": [
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Oceanside",
          "state": "California"
        },
        {
          "city": "Pomona",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04003142"
    },
    {
      "nct_id": "NCT07042516",
      "title": "Safety and Efficacy of Asimadoline (TP0052) in Patients With Vasomotor Symptoms (VMS).",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Vasomotor Symptoms"
      ],
      "interventions": [
        {
          "name": "Asimadoline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Tioga Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "62 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 62 Years · Female only"
      },
      "enrollment_count": 120,
      "start_date": "2025-08-13",
      "completion_date": "2027-02-20",
      "has_results": false,
      "last_update_posted_date": "2025-09-09",
      "last_synced_at": "2026-06-26T06:23:48.449Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07042516"
    },
    {
      "nct_id": "NCT00066144",
      "title": "Use of Black Cohosh and Red Clover for the Relief of Menopausal Symptoms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Hot Flashes",
        "Menopause"
      ],
      "interventions": [
        {
          "name": "Cimicifuga racemosa",
          "type": "DRUG"
        },
        {
          "name": "Trifolium pratense",
          "type": "DRUG"
        },
        {
          "name": "Black cohosh",
          "type": "DRUG"
        },
        {
          "name": "Red clover",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Center for Complementary and Integrative Health (NCCIH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 112,
      "start_date": "2003-04",
      "completion_date": "2006-04",
      "has_results": false,
      "last_update_posted_date": "2007-10-12",
      "last_synced_at": "2026-06-26T06:23:48.449Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00066144"
    },
    {
      "nct_id": "NCT02234362",
      "title": "Vortioxetine for Menopausal Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Depression",
        "Menopause",
        "Vasomotor Disturbance",
        "Hot Flashes",
        "Sleep"
      ],
      "interventions": [
        {
          "name": "vortioxetine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "62 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 62 Years · Female only"
      },
      "enrollment_count": 47,
      "start_date": "2015-06-12",
      "completion_date": "2016-09-29",
      "has_results": true,
      "last_update_posted_date": "2017-06-28",
      "last_synced_at": "2026-06-26T06:23:48.449Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02234362"
    },
    {
      "nct_id": "NCT05073237",
      "title": "Effects of Novel Estrogens on Glucose and Lipids in Postmenopausal Prediabetic Women Veterans",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Menopause",
        "Prediabetes",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "OTHER"
        },
        {
          "name": "conjugated estrogens/bazedoxifene (CE/BZA)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "50 Years to 60 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2024-04-08",
      "completion_date": "2024-04-08",
      "has_results": false,
      "last_update_posted_date": "2024-05-10",
      "last_synced_at": "2026-06-26T06:23:48.449Z",
      "location_count": 1,
      "location_summary": "New Orleans, Louisiana",
      "locations": [
        {
          "city": "New Orleans",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05073237"
    },
    {
      "nct_id": "NCT05312567",
      "title": "FP-101 Versus Placebo in the Treatment of Menopausal Vasomotor Symptoms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Vasomotor Symptoms",
        "Menopause"
      ],
      "interventions": [
        {
          "name": "FP-101",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Fervent Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "46 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "46 Years and older · Female only"
      },
      "enrollment_count": 105,
      "start_date": "2021-03-24",
      "completion_date": "2023-07-31",
      "has_results": false,
      "last_update_posted_date": "2023-10-26",
      "last_synced_at": "2026-06-26T06:23:48.449Z",
      "location_count": 12,
      "location_summary": "Lomita, California • Long Beach, California • West Covina, California + 8 more",
      "locations": [
        {
          "city": "Lomita",
          "state": "California"
        },
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "West Covina",
          "state": "California"
        },
        {
          "city": "Hialeah",
          "state": "Florida"
        },
        {
          "city": "Miami Lakes",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05312567"
    }
  ]
}