{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Mental+Impairment&page=3",
    "query": {
      "condition": "Mental Impairment",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 1464,
    "total_pages": 147,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Mental+Impairment&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Mental+Impairment&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-07T18:34:51.926Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06335173",
      "title": "A Study to Evaluate Efficacy and Safety of Intravenous Sabirnetug in Participants With Early Alzheimer's Disease (ALTITUDE-AD)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "sabirnetug",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Acumen Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "50 Years to 90 Years"
      },
      "enrollment_count": 542,
      "start_date": "2024-02-29",
      "completion_date": "2026-10",
      "has_results": false,
      "last_update_posted_date": "2025-10-27",
      "last_synced_at": "2026-10-07T18:34:51.926Z",
      "location_count": 44,
      "location_summary": "Carlsbad, California • Fullerton, California • Irvine, California + 40 more",
      "locations": [
        {
          "city": "Carlsbad",
          "state": "California"
        },
        {
          "city": "Fullerton",
          "state": "California"
        },
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Santa Ana",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06335173"
    },
    {
      "nct_id": "NCT05150990",
      "title": "Technology and Family Thriving Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alzheimer Disease",
        "Dementia",
        "Caregiver Burnout",
        "Quality of Life",
        "Mental Health Wellness 1",
        "Loneliness",
        "Family Relationship"
      ],
      "interventions": [
        {
          "name": "Virtual Reality",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Video Chat",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, Santa Barbara",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 186,
      "start_date": "2021-10-02",
      "completion_date": "2024-03-16",
      "has_results": true,
      "last_update_posted_date": "2026-07-29",
      "last_synced_at": "2026-10-07T18:34:51.926Z",
      "location_count": 27,
      "location_summary": "Calabasas, California • Camarillo, California • Goleta, California + 16 more",
      "locations": [
        {
          "city": "Calabasas",
          "state": "California"
        },
        {
          "city": "Camarillo",
          "state": "California"
        },
        {
          "city": "Goleta",
          "state": "California"
        },
        {
          "city": "Montecito",
          "state": "California"
        },
        {
          "city": "Ojai",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05150990"
    },
    {
      "nct_id": "NCT00319891",
      "title": "Computer-Based Training for Mild Alzheimer's Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Alzheimer's Disease"
      ],
      "interventions": [
        {
          "name": "Computer-based Cognitive Training",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Posit Science Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "60 Years to 90 Years"
      },
      "enrollment_count": 6,
      "start_date": "2004-09",
      "completion_date": "2006-10",
      "has_results": false,
      "last_update_posted_date": "2013-05-15",
      "last_synced_at": "2026-10-07T18:34:51.926Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00319891"
    },
    {
      "nct_id": "NCT04790630",
      "title": "Cognitive Fitness for Depression in Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression Mild",
        "Depressive Disorder, Major",
        "Mild Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "Computerized Cognitive Remediation of Executive Functioning (CCR-EF)",
          "type": "OTHER"
        },
        {
          "name": "Active Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "UConn Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 38,
      "start_date": "2020-11-15",
      "completion_date": "2024-10-15",
      "has_results": true,
      "last_update_posted_date": "2026-04-29",
      "last_synced_at": "2026-10-07T18:34:51.926Z",
      "location_count": 1,
      "location_summary": "Farmington, Connecticut",
      "locations": [
        {
          "city": "Farmington",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04790630"
    },
    {
      "nct_id": "NCT00000392",
      "title": "Phase II Study of the Efficacy of Peptide T in HIV-Positive Individuals With Cognitive Impairment.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "HIV Infections",
        "Cognition Disorders"
      ],
      "interventions": [
        {
          "name": "Peptide T",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 215,
      "start_date": "1990-01",
      "completion_date": "1996-08",
      "has_results": true,
      "last_update_posted_date": "2017-02-28",
      "last_synced_at": "2026-10-07T18:34:51.926Z",
      "location_count": 3,
      "location_summary": "Los Angeles, California • San Diego, California • Miami, Florida",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00000392"
    },
    {
      "nct_id": "NCT05515224",
      "title": "5-Cog 2.0: A Pragmatic Clinical Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dementia",
        "Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "5-Cog Paradigm (5-Cog battery coupled with clinical decision tool)",
          "type": "OTHER"
        },
        {
          "name": "Enhanced usual care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Albert Einstein College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 6600,
      "start_date": "2023-08-18",
      "completion_date": "2027-11",
      "has_results": false,
      "last_update_posted_date": "2026-04-17",
      "last_synced_at": "2026-10-07T18:34:51.926Z",
      "location_count": 2,
      "location_summary": "Bloomington, Indiana • The Bronx, New York",
      "locations": [
        {
          "city": "Bloomington",
          "state": "Indiana"
        },
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05515224"
    },
    {
      "nct_id": "NCT06366724",
      "title": "LIFT: Life Improvement Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "ME/CFS",
        "Long COVID",
        "PASC"
      ],
      "interventions": [
        {
          "name": "Pyridostigmine",
          "type": "DRUG"
        },
        {
          "name": "Low-Dose Naltrexone",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 160,
      "start_date": "2024-09-10",
      "completion_date": "2026-11",
      "has_results": false,
      "last_update_posted_date": "2025-10-22",
      "last_synced_at": "2026-10-07T18:34:51.926Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06366724"
    },
    {
      "nct_id": "NCT05235113",
      "title": "Remote Game-based Exercise Program for Cognitive and Motor Function Improvement",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mild Cognitive Impairment",
        "Dementia",
        "Cognitive Impairment",
        "Memory Loss"
      ],
      "interventions": [
        {
          "name": "Tele-Exergame Platform",
          "type": "DEVICE"
        },
        {
          "name": "No Tele-Exergame Platform",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 84,
      "start_date": "2023-11-03",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-15",
      "last_synced_at": "2026-10-07T18:34:51.926Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California • Houston, Texas",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05235113"
    },
    {
      "nct_id": "NCT05900310",
      "title": "Linus Health CDS Retrospective Validation Study",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cognitive Impairment",
        "Motor Disorders",
        "Dementia"
      ],
      "interventions": [
        {
          "name": "Core Cognitive Evaluation (CCE)",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Linus Health, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2023-06",
      "completion_date": "2023-08",
      "has_results": false,
      "last_update_posted_date": "2023-06-12",
      "last_synced_at": "2026-10-07T18:34:51.926Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05900310"
    },
    {
      "nct_id": "NCT05690243",
      "title": "Minds Navigating the Diagnosis of Mild Cognitive Impairment",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cognitive Dysfunction",
        "Mild Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "Group psychotherapy delivered via video telehealth",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Tuscaloosa Research & Education Advancement Corporation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 160,
      "start_date": "2023-10-01",
      "completion_date": "2025-09-30",
      "has_results": false,
      "last_update_posted_date": "2023-11-24",
      "last_synced_at": "2026-10-07T18:34:51.926Z",
      "location_count": 2,
      "location_summary": "Tuscaloosa, Alabama • Salem, Virginia",
      "locations": [
        {
          "city": "Tuscaloosa",
          "state": "Alabama"
        },
        {
          "city": "Salem",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05690243"
    }
  ]
}