{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Metabolic+Dysfunction-steatohepatitis+%28MASH%29&page=2", "query": { "condition": "Metabolic Dysfunction-steatohepatitis (MASH)", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 47, "total_pages": 5, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Metabolic+Dysfunction-steatohepatitis+%28MASH%29&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Metabolic+Dysfunction-steatohepatitis+%28MASH%29&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-08T18:43:05.744Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT07527910", "title": "A Phase 2a Study of ALN-PNP With and Without a GLP1R Agonist in Adult Patients With Homozygous PNPLA3-Related MASLD", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)" ], "interventions": [ { "name": "ALN-PNP", "type": "DRUG" }, { "name": "Tirzepatide", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Regeneron Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 204, "start_date": "2026-05-22", "completion_date": "2030-03-15", "has_results": false, "last_update_posted_date": "2026-09-29", "last_synced_at": "2026-10-08T18:43:05.744Z", "location_count": 9, "location_summary": "Tucson, Arizona • Coronado, California • Pasadena, California + 6 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Coronado", "state": "California" }, { "city": "Pasadena", "state": "California" }, { "city": "Jupiter", "state": "Florida" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT07527910" }, { "nct_id": "NCT06108219", "title": "A Phase 2b, Study Evaluating Miricorilant in Adult Patients With Nonalcoholic Steatohepatitis/Metabolic Dysfunction-Associated Steatohepatitis (MONARCH)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Nonalcoholic Steatohepatitis (NASH)", "Metabolic Dysfunction-associated Steatohepatitis (MASH)" ], "interventions": [ { "name": "Miricorilant (Cohort A)", "type": "DRUG" }, { "name": "Placebo (Cohort A)", "type": "DRUG" }, { "name": "Miricorilant (Cohort B)", "type": "DRUG" }, { "name": "Placebo (Cohort B)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Corcept Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 175, "start_date": "2023-10-25", "completion_date": "2026-08-24", "has_results": false, "last_update_posted_date": "2026-09-29", "last_synced_at": "2026-10-08T18:43:05.744Z", "location_count": 48, "location_summary": "Chandler, Arizona • Tucson, Arizona • Huntington Park, California + 41 more", "locations": [ { "city": "Chandler", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Huntington Park", "state": "California" }, { "city": "Lancaster", "state": "California" }, { "city": "Long Beach", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06108219" }, { "nct_id": "NCT07795164", "title": "Phase 3 Study of the Efficacy, Safety, and Clinical Outcomes of Pemvidutide in MASH", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Metabolic Dysfunction-Associated Steatohepatitis (MASH)" ], "interventions": [ { "name": "Pemvidutide", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Altimmune, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 1800, "start_date": "2026-07-30", "completion_date": "2032-12", "has_results": false, "last_update_posted_date": "2026-09-23", "last_synced_at": "2026-10-08T18:43:05.744Z", "location_count": 9, "location_summary": "North Little Rock, Arkansas • Fountain Valley, California • Fresno, California + 6 more", "locations": [ { "city": "North Little Rock", "state": "Arkansas" }, { "city": "Fountain Valley", "state": "California" }, { "city": "Fresno", "state": "California" }, { "city": "Gardena", "state": "California" }, { "city": "Long Beach", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07795164" }, { "nct_id": "NCT05519475", "title": "A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Metabolic Dysfunction-Associated SteatoHepatitis (MASH)" ], "interventions": [ { "name": "ALN-HSD", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Regeneron Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 120, "start_date": "2023-02-09", "completion_date": "2028-12-07", "has_results": false, "last_update_posted_date": "2026-10-08", "last_synced_at": "2026-10-08T18:43:05.744Z", "location_count": 61, "location_summary": "Flagstaff, Arizona • Peoria, Arizona • Tucson, Arizona + 46 more", "locations": [ { "city": "Flagstaff", "state": "Arizona" }, { "city": "Peoria", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT05519475" }, { "nct_id": "NCT06419374", "title": "A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis" ], "interventions": [ { "name": "Pegozafermin", "type": "BIOLOGICAL" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "89bio, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 762, "start_date": "2024-05-24", "completion_date": "2031-08", "has_results": false, "last_update_posted_date": "2026-10-05", "last_synced_at": "2026-10-08T18:43:05.744Z", "location_count": 150, "location_summary": "Birmingham, Alabama • Homewood, Alabama • Chandler, Arizona + 123 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Homewood", "state": "Alabama" }, { "city": "Chandler", "state": "Arizona" }, { "city": "Flagstaff", "state": "Arizona" }, { "city": "Peoria", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT06419374" }, { "nct_id": "NCT07335601", "title": "Study to Evaluate Resmetirom in Post-Liver Transplant Patients With MASH", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "MASH - Metabolic Dysfunction-Associated Steatohepatitis" ], "interventions": [ { "name": "Resmetirom", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Madrigal Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 120, "start_date": "2025-12-29", "completion_date": "2029-03", "has_results": false, "last_update_posted_date": "2026-08-26", "last_synced_at": "2026-10-08T18:43:05.744Z", "location_count": 16, "location_summary": "La Jolla, California • Los Angeles, California • San Francisco, California + 12 more", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Washington D.C.", "state": "District of Columbia" } ], "official_url": "https://clinicaltrials.gov/study/NCT07335601" }, { "nct_id": "NCT06824974", "title": "Time-restricted Eating and Healthy Eating in Patients With Metabolic Liver Disease or Cancer", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Liver Cancer, Adult", "MASH - Metabolic Dysfunction-Associated Steatohepatitis", "Obesity and Overweight" ], "interventions": [ { "name": "Time-restricted eating plus healthy diet", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of California, San Diego", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 50, "start_date": "2025-08-01", "completion_date": "2028-12", "has_results": false, "last_update_posted_date": "2026-06-25", "last_synced_at": "2026-10-08T18:43:05.744Z", "location_count": 1, "location_summary": "La Jolla, California", "locations": [ { "city": "La Jolla", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06824974" }, { "nct_id": "NCT06797596", "title": "Clinical Correlation Evaluation of the LIVERFASt Test for Diagnosing Important Liver Lesions of Fibrosis and Steatosis Against Magnetic Resonance Elastography (MRE) for Liver Fibrosis and MR-based Assessment of Steatosis, in Adult US Population.", "overall_status": "NOT_YET_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Liver Fibrosis Due to NASH", "MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease", "Alcohol Liver Disease" ], "interventions": [], "intervention_types": [], "sponsor": "Fibronostics USA, Inc", "sponsor_class": "OTHER", "healthy_volunteers": null, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 100, "start_date": "2025-05", "completion_date": "2025-08-30", "has_results": false, "last_update_posted_date": "2025-03-13", "last_synced_at": "2026-10-08T18:43:05.744Z", "location_count": 1, "location_summary": "Lady Lake, Florida", "locations": [ { "city": "Lady Lake", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT06797596" }, { "nct_id": "NCT06632444", "title": "LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Metabolic Dysfunction Associated Steatohepatitis (MASH)", "Liver Fibrosis" ], "interventions": [ { "name": "Survodutide", "type": "COMBINATION_PRODUCT" }, { "name": "Placebo", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "COMBINATION_PRODUCT" ], "sponsor": "Boehringer Ingelheim", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1800, "start_date": "2024-10-14", "completion_date": "2031-12-27", "has_results": false, "last_update_posted_date": "2026-10-01", "last_synced_at": "2026-10-08T18:43:05.744Z", "location_count": 165, "location_summary": "Birmingham, Alabama • Peoria, Arizona • Scottsdale, Arizona + 132 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Peoria", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT06632444" }, { "nct_id": "NCT07680478", "title": "Nutrition Intervention Combined With Resmetirom for MASH", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Metabolic Dysfunction-Associated Steatohepatitis (MASH)" ], "interventions": [ { "name": "Resmetirom therapy", "type": "DRUG" }, { "name": "Comprehensive nutritional intervention", "type": "BEHAVIORAL" }, { "name": "Standard dietary support", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "City University of New York", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 120, "start_date": "2026-10-01", "completion_date": "2028-06-30", "has_results": false, "last_update_posted_date": "2026-07-06", "last_synced_at": "2026-10-08T18:43:05.744Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT07680478" } ] }