{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Metabolic+Side+Effects+of+Drugs&page=2", "query": { "condition": "Metabolic Side Effects of Drugs", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Metabolic+Side+Effects+of+Drugs&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-07-23T14:55:02.705Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03383133", "title": "Studies of Sulfur Metabolism in Humans", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Metabolic Side Effects of Drugs" ], "interventions": [ { "name": "SULT Allosteric Inhibition", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Albert Einstein College of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "61 Years", "maximum_age": "61 Years", "sex": "MALE", "summary": "61 Years to 61 Years · Male only" }, "enrollment_count": 1, "start_date": "2018-01-11", "completion_date": "2023-02-02", "has_results": false, "last_update_posted_date": "2023-10-27", "last_synced_at": "2026-07-23T14:55:02.705Z", "location_count": 1, "location_summary": "The Bronx, New York", "locations": [ { "city": "The Bronx", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT03383133" }, { "nct_id": "NCT00004036", "title": "Combination Chemotherapy Plus Amifostine in Treating Patients With Advanced Cancer", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Chronic Myeloproliferative Disorders", "Drug/Agent Toxicity by Tissue/Organ", "Leukemia", "Lymphoma", "Multiple Myeloma and Plasma Cell Neoplasm", "Myelodysplastic Syndromes", "Precancerous Condition", "Unspecified Adult Solid Tumor, Protocol Specific" ], "interventions": [ { "name": "sargramostim", "type": "BIOLOGICAL" }, { "name": "amifostine trihydrate", "type": "DRUG" }, { "name": "carboplatin", "type": "DRUG" }, { "name": "cyclophosphamide", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "The Cleveland Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 30, "start_date": "1997-11", "completion_date": null, "has_results": false, "last_update_posted_date": "2013-12-19", "last_synced_at": "2026-07-23T14:55:02.705Z", "location_count": 1, "location_summary": "Cleveland, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT00004036" }, { "nct_id": "NCT03825224", "title": "Evaluation of MyoStrain™ in Clinical Practice", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Cardiac Failure", "Coronary Artery Disease", "Sarcoidosis", "Amyloidosis", "Lupus", "Myocarditis", "Drug Toxicity" ], "interventions": [ { "name": "Diagnostic Test: Myostrain", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "University of Kansas Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": null, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 19, "start_date": "2019-04-15", "completion_date": "2019-11-15", "has_results": false, "last_update_posted_date": "2019-11-19", "last_synced_at": "2026-07-23T14:55:02.705Z", "location_count": 1, "location_summary": "Kansas City, Kansas", "locations": [ { "city": "Kansas City", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03825224" }, { "nct_id": "NCT06322238", "title": "Pharmacogenetic Panel to Prevent Adverse Drug Reactions in Daily Primary Care Practice:", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pharmacogenomic Drug Interaction", "Side Effect of Drug", "Ineffective Drug Action", "Drug Metabolism, Poor, CYP2D6-Related", "Drug Metabolism, Poor, CYP2C19-Related" ], "interventions": [ { "name": "PGx panel test", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 66, "start_date": "2024-12-01", "completion_date": "2027-04", "has_results": false, "last_update_posted_date": "2025-10-14", "last_synced_at": "2026-07-23T14:55:02.705Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT06322238" }, { "nct_id": "NCT00746252", "title": "Side Effect Study of Antipsychotic Medicines to Treat Childhood Bipolar Disorder", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Bipolar Disorder" ], "interventions": [ { "name": "risperidone", "type": "DRUG" }, { "name": "aripiprazole", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Maryland, Baltimore", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "7 Years", "maximum_age": "12 Years", "sex": "ALL", "summary": "7 Years to 12 Years" }, "enrollment_count": 5, "start_date": "2008-06", "completion_date": "2010-10", "has_results": true, "last_update_posted_date": "2020-01-06", "last_synced_at": "2026-07-23T14:55:02.705Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00746252" }, { "nct_id": "NCT00363181", "title": "Side Effects of Antipsychotic Medications", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Insulin Resistance", "Metabolic Syndrome X", "Schizophrenia and Disorders With Psychotic Features", "Mood Disorders", "Psychotic Disorders" ], "interventions": [], "intervention_types": [], "sponsor": "Stanford University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": "66 Years", "sex": "ALL", "summary": "30 Years to 66 Years" }, "enrollment_count": 76, "start_date": "2006-04", "completion_date": "2011-12", "has_results": false, "last_update_posted_date": "2021-03-22", "last_synced_at": "2026-07-23T14:55:02.705Z", "location_count": 1, "location_summary": "Palo Alto, California", "locations": [ { "city": "Palo Alto", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00363181" }, { "nct_id": "NCT00052884", "title": "Amifostine and Melphalan in Treating Patients With Primary Systemic Amyloidosis Who Are Undergoing Peripheral Stem Cell Transplantation", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Drug/Agent Toxicity by Tissue/Organ", "Multiple Myeloma and Plasma Cell Neoplasm" ], "interventions": [ { "name": "filgrastim", "type": "BIOLOGICAL" }, { "name": "amifostine trihydrate", "type": "DRUG" }, { "name": "melphalan", "type": "DRUG" }, { "name": "bone marrow ablation with stem cell support", "type": "PROCEDURE" }, { "name": "peripheral blood stem cell transplantation", "type": "PROCEDURE" } ], "intervention_types": [ "BIOLOGICAL", "DRUG", "PROCEDURE" ], "sponsor": "Eastern Cooperative Oncology Group", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 8, "start_date": "2004-01-22", "completion_date": "2011-03", "has_results": false, "last_update_posted_date": "2023-06-18", "last_synced_at": "2026-07-23T14:55:02.705Z", "location_count": 16, "location_summary": "Scottsdale, Arizona • Indianapolis, Indiana • Burnsville, Minnesota + 12 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "Burnsville", "state": "Minnesota" }, { "city": "Coon Rapids", "state": "Minnesota" }, { "city": "Edina", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT00052884" }, { "nct_id": "NCT02378220", "title": "Pharmacogenetic Testing Among Home Health Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Adverse Drug Events", "Adverse Drug Reactions", "Drug Interaction Potentiation", "Drug Metabolism, Poor, CYP2D6-RELATED", "Drug Metabolism, Poor, CYP2C19-RELATED", "Cytochrome P450 Enzyme Deficiency", "Cytochrome P450 CYP2D6 Enzyme Deficiency", "Cytochrome P450 CYP2C9 Enzyme Deficiency", "Cytochrome P450 CYP2C19 Enzyme Deficiency", "Cytochrome P450 CYP3A Enzyme Deficiency", "Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant", "Poor Metabolizer Due to Cytochrome p450 CYP2C19 Variant", "Poor Metabolizer Due to Cytochrome P450 CYP2D6 Variant" ], "interventions": [ { "name": "Pharmacogenetic testing", "type": "GENETIC" } ], "intervention_types": [ "GENETIC" ], "sponsor": "Genelex Corporation", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "ALL", "summary": "50 Years and older" }, "enrollment_count": 110, "start_date": "2015-03", "completion_date": "2016-03", "has_results": true, "last_update_posted_date": "2019-09-20", "last_synced_at": "2026-07-23T14:55:02.705Z", "location_count": 1, "location_summary": "Searcy, Arkansas", "locations": [ { "city": "Searcy", "state": "Arkansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02378220" }, { "nct_id": "NCT02081872", "title": "Utility of PharmacoGenomics for Reducing Adverse Drug Effects", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Genetics of Drug Metabolism" ], "interventions": [], "intervention_types": [], "sponsor": "Companion Dx Reference Lab, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 279000, "start_date": "2014-04", "completion_date": "2017-07", "has_results": false, "last_update_posted_date": "2015-10-08", "last_synced_at": "2026-07-23T14:55:02.705Z", "location_count": 41, "location_summary": "Scottsdale, Arizona • Augusta, Arkansas • Arcadia, California + 38 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Augusta", "state": "Arkansas" }, { "city": "Arcadia", "state": "California" }, { "city": "El Cajon", "state": "California" }, { "city": "Newark", "state": "Delaware" } ], "official_url": "https://clinicaltrials.gov/study/NCT02081872" }, { "nct_id": "NCT01490060", "title": "Fosaprepitant in Patients Receiving Ifosfamide-based Regimen", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Sarcoma", "Chemotherapy-induced Nausea and Vomiting", "Effects of Chemotherapy", "Adverse Effects of Medical Drugs" ], "interventions": [ { "name": "Fosaprepitant", "type": "DRUG" }, { "name": "Dexamethasone", "type": "DRUG" }, { "name": "5HT3 receptor antagonist", "type": "DRUG" }, { "name": "Ifosfamide-based chemotherapy (AI)", "type": "DRUG" }, { "name": "Doxorubicin", "type": "DRUG" }, { "name": "Mesna", "type": "DRUG" }, { "name": "Ifosfamide", "type": "DRUG" }, { "name": "Vincristine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 47, "start_date": "2012-05", "completion_date": "2016-03", "has_results": true, "last_update_posted_date": "2016-04-11", "last_synced_at": "2026-07-23T14:55:02.705Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01490060" } ] }