{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Metabolism+Changes&page=21",
    "query": {
      "condition": "Metabolism Changes",
      "page": 21
    },
    "page_size": 10
  },
  "pagination": {
    "page": 21,
    "page_size": 10,
    "total_count": 1515,
    "total_pages": 152,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Metabolism+Changes&page=22&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Metabolism+Changes&page=20&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-23T02:17:45.756Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00228579",
      "title": "Assessment of Changes in Abdominal Fat",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Obesity"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 65 Years · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2003-06",
      "completion_date": "2020-12",
      "has_results": false,
      "last_update_posted_date": "2022-08-05",
      "last_synced_at": "2026-10-23T02:17:45.756Z",
      "location_count": 1,
      "location_summary": "West Lafayette, Indiana",
      "locations": [
        {
          "city": "West Lafayette",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00228579"
    },
    {
      "nct_id": "NCT01833507",
      "title": "Physical Activity and Health Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Overweight",
        "Obese"
      ],
      "interventions": [
        {
          "name": "Self-Exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual Care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 130,
      "start_date": "2013-04",
      "completion_date": "2015-04",
      "has_results": false,
      "last_update_posted_date": "2016-01-14",
      "last_synced_at": "2026-10-23T02:17:45.756Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01833507"
    },
    {
      "nct_id": "NCT01134458",
      "title": "Personalized Cardiovascular Risk Information to Initiate and Maintain Health Behavior Changes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiovascular Disease",
        "Peripheral Artery Disease",
        "Ischemic Stroke",
        "Diabetes"
      ],
      "interventions": [
        {
          "name": "Web-Based Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 98,
      "start_date": "2010-12",
      "completion_date": "2014-02",
      "has_results": false,
      "last_update_posted_date": "2014-07-22",
      "last_synced_at": "2026-10-23T02:17:45.756Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01134458"
    },
    {
      "nct_id": "NCT01923350",
      "title": "Avoiding Diabetes After Pregnancy Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Weight Reduction"
      ],
      "interventions": [
        {
          "name": "Weight Reduction Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Weight Reduction Control Arm",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Tested for diabetes",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Not tested for diabetes",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Social & Scientific Systems Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 140,
      "start_date": "2011-12",
      "completion_date": "2013-03",
      "has_results": false,
      "last_update_posted_date": "2013-08-15",
      "last_synced_at": "2026-10-23T02:17:45.756Z",
      "location_count": 1,
      "location_summary": "Silver Spring, Maryland",
      "locations": [
        {
          "city": "Silver Spring",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01923350"
    },
    {
      "nct_id": "NCT01433484",
      "title": "Heart-Healthy Lenoir Lifestyle Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiovascular Disease",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Maintenance of Weight Loss--Control",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Maintenance of Weight Loss--Experimental",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 339,
      "start_date": "2011-09",
      "completion_date": "2014-10",
      "has_results": false,
      "last_update_posted_date": "2017-11-20",
      "last_synced_at": "2026-10-23T02:17:45.756Z",
      "location_count": 1,
      "location_summary": "Kinston, North Carolina",
      "locations": [
        {
          "city": "Kinston",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01433484"
    },
    {
      "nct_id": "NCT00998348",
      "title": "Study of Parenting Intervention to Prevent Child Obesity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Parenting Program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 324,
      "start_date": "2009-07",
      "completion_date": "2012-06",
      "has_results": false,
      "last_update_posted_date": "2013-06-17",
      "last_synced_at": "2026-10-23T02:17:45.756Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00998348"
    },
    {
      "nct_id": "NCT02324361",
      "title": "Quincy Family, Youth & Technology For Lifestyle Change (FYT-4-LIFE) Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pediatric Obesity"
      ],
      "interventions": [
        {
          "name": "Physical Activity",
          "type": "OTHER"
        },
        {
          "name": "Evidence-based information on healthy family routines",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "7 Years",
        "sex": "ALL",
        "summary": "3 Years to 7 Years"
      },
      "enrollment_count": 48,
      "start_date": "2014-07",
      "completion_date": "2015-02",
      "has_results": true,
      "last_update_posted_date": "2020-10-22",
      "last_synced_at": "2026-10-23T02:17:45.756Z",
      "location_count": 1,
      "location_summary": "Quincy, Massachusetts",
      "locations": [
        {
          "city": "Quincy",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02324361"
    },
    {
      "nct_id": "NCT03244722",
      "title": "Maternal Metabolic and Molecular Changes Induced by Preconception Weight Loss and Their Effects on Birth Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity; Familial",
        "Pregnancy Related"
      ],
      "interventions": [
        {
          "name": "Very-low energy Diet (VLED)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Standard of care (SOC)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 147,
      "start_date": "2018-04-10",
      "completion_date": "2025-08-29",
      "has_results": true,
      "last_update_posted_date": "2026-09-04",
      "last_synced_at": "2026-10-23T02:17:45.756Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03244722"
    },
    {
      "nct_id": "NCT03646370",
      "title": "Assessing Virologic Success and Metabolic Changes in Patients Switching From a TDF to TAF Containing Antiretroviral Therapy Regimen",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "HIV-1-infection",
        "Metabolic Syndrome",
        "Cardiovascular Diseases",
        "Weight Gain",
        "Renal Function Abnormal",
        "Hyperglycemia"
      ],
      "interventions": [
        {
          "name": "Tenofovir Alafenamide",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 110,
      "start_date": "2018-07-25",
      "completion_date": "2019-07-24",
      "has_results": false,
      "last_update_posted_date": "2019-09-23",
      "last_synced_at": "2026-10-23T02:17:45.756Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03646370"
    },
    {
      "nct_id": "NCT03422380",
      "title": "Energy Expenditure and Weight Loss Maintenance",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Obesity",
        "Weight Change, Body",
        "Weight Loss",
        "Physical Activity"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 112,
      "start_date": "2009-10",
      "completion_date": "2012-09",
      "has_results": false,
      "last_update_posted_date": "2018-02-05",
      "last_synced_at": "2026-10-23T02:17:45.756Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03422380"
    }
  ]
}