{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Metabolism+Changes&page=9",
    "query": {
      "condition": "Metabolism Changes",
      "page": 9
    },
    "page_size": 10
  },
  "pagination": {
    "page": 9,
    "page_size": 10,
    "total_count": 1514,
    "total_pages": 152,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Metabolism+Changes&page=10&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Metabolism+Changes&page=8&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-21T23:22:59.739Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01067963",
      "title": "Self-Management and Resourceful Transition of Type 2 Diabetes With Stage 3 Kidney Disease",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus, Type 2",
        "Renal Insufficiency, Chronic"
      ],
      "interventions": [
        {
          "name": "Computer assisted education and motivational interviewing.",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Group talks/social chat",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 80,
      "start_date": "2009-12",
      "completion_date": "2012-10",
      "has_results": false,
      "last_update_posted_date": "2015-06-09",
      "last_synced_at": "2026-10-21T23:22:59.739Z",
      "location_count": 2,
      "location_summary": "Aurora, Colorado • Denver, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01067963"
    },
    {
      "nct_id": "NCT05625321",
      "title": "Stepping Into Lifestyle Changes",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overweight and Obesity",
        "Pre-Diabetes",
        "High Blood Pressure"
      ],
      "interventions": [
        {
          "name": "Educational Group Weight Loss Classes",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Home Gardening Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "30 Years and older · Female only"
      },
      "enrollment_count": 273,
      "start_date": "2023-03-27",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-08-27",
      "last_synced_at": "2026-10-21T23:22:59.739Z",
      "location_count": 2,
      "location_summary": "Birmingham, Alabama • Jackson, Mississippi",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Jackson",
          "state": "Mississippi"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05625321"
    },
    {
      "nct_id": "NCT04393909",
      "title": "Improving Safety of Diagnosis and Therapy in the Inpatient Setting",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Delirium",
        "Confusion",
        "Mental Status Change",
        "Back Pain",
        "Hip Pain Chronic",
        "Chest Pain",
        "Asthma",
        "COPD",
        "Cellulitis",
        "Soft Tissue Infections",
        "Cough",
        "Deep Vein Thrombosis",
        "Pulmonary Embolism",
        "Venous Thromboembolism",
        "Dyspnea",
        "Electrolyte Metabolism Abnormal",
        "Fever",
        "Failure to Thrive",
        "Weakness",
        "Protein-Calorie Malnutrition",
        "Headache",
        "Neck Pain",
        "Hypoxia",
        "Pneumonia",
        "Sepsis",
        "Syncope",
        "Vomiting",
        "Diarrhea",
        "Leg Pain",
        "Abdominal Pain"
      ],
      "interventions": [
        {
          "name": "Diagnostic Uncertainty Educational Curriculum",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Diagnostic Timeout",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Diagnostic (Dx) Questionnaire",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enhancements to Epic-integrated Quality & Safety Dashboard",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 700,
      "start_date": "2019-07-01",
      "completion_date": "2021-12-30",
      "has_results": false,
      "last_update_posted_date": "2022-07-26",
      "last_synced_at": "2026-10-21T23:22:59.739Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04393909"
    },
    {
      "nct_id": "NCT01370109",
      "title": "Cardiovascular Effects of Sunitinib Therapy (CREST)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Renal Cell Carcinoma 4"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Abramson Cancer Center at Penn Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 98,
      "start_date": "2011-04",
      "completion_date": "2017-12-31",
      "has_results": false,
      "last_update_posted_date": "2018-10-02",
      "last_synced_at": "2026-10-21T23:22:59.739Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01370109"
    },
    {
      "nct_id": "NCT01682733",
      "title": "Endoscopic Gastric Reduction for Weight Management",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Botulinum toxin",
          "type": "DRUG"
        },
        {
          "name": "Overstitch Endoscopic Suturing System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 10,
      "start_date": "2012-08",
      "completion_date": "2014-12",
      "has_results": false,
      "last_update_posted_date": "2015-04-07",
      "last_synced_at": "2026-10-21T23:22:59.739Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01682733"
    },
    {
      "nct_id": "NCT03899311",
      "title": "A Protein-sparing Modified Fast for Children and Adolescents With Severe Obesity (PSMF)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Obesity, Childhood"
      ],
      "interventions": [
        {
          "name": "protein-sparing modified fast diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Ihuoma Eneli",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "19 Years",
        "sex": "ALL",
        "summary": "11 Years to 19 Years"
      },
      "enrollment_count": 30,
      "start_date": "2016-01-01",
      "completion_date": "2019-02-28",
      "has_results": false,
      "last_update_posted_date": "2019-04-02",
      "last_synced_at": "2026-10-21T23:22:59.739Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03899311"
    },
    {
      "nct_id": "NCT01354574",
      "title": "Thermic & Lipemic Properties of Dietary Carbohydrates",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Exogenous Obesity",
        "Dietary Modification"
      ],
      "interventions": [
        {
          "name": "High Glycemic Index meals",
          "type": "OTHER"
        },
        {
          "name": "Low Glycemic Index meals",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "USDA, Western Human Nutrition Research Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "48 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 48 Years · Female only"
      },
      "enrollment_count": 28,
      "start_date": "2002-10",
      "completion_date": "2005-06",
      "has_results": false,
      "last_update_posted_date": "2011-07-13",
      "last_synced_at": "2026-10-21T23:22:59.739Z",
      "location_count": 1,
      "location_summary": "Davis, California",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01354574"
    },
    {
      "nct_id": "NCT04896060",
      "title": "The Impact of the COVID-19 Pandemic on Eating Behavior and Weight Change",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "COVID-19",
        "Obesity"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 5056,
      "start_date": "2022-09-01",
      "completion_date": "2025-02-13",
      "has_results": false,
      "last_update_posted_date": "2026-08-28",
      "last_synced_at": "2026-10-21T23:22:59.739Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04896060"
    },
    {
      "nct_id": "NCT00265980",
      "title": "Leptin in Human Energy and Neuroendocrine Homeostasis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Weight Loss"
      ],
      "interventions": [
        {
          "name": "Subcutaneous Placebo",
          "type": "DRUG"
        },
        {
          "name": "Leptin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "19 Years to 45 Years"
      },
      "enrollment_count": 22,
      "start_date": "2002-07",
      "completion_date": "2013-07",
      "has_results": true,
      "last_update_posted_date": "2019-09-18",
      "last_synced_at": "2026-10-21T23:22:59.739Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00265980"
    },
    {
      "nct_id": "NCT02596776",
      "title": "Cold Induced Changes in White Adipose",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Obese",
        "Normal Body Weight",
        "Prediabetes",
        "Metabolic Syndrome"
      ],
      "interventions": [
        {
          "name": "Fat biopsy",
          "type": "PROCEDURE"
        },
        {
          "name": "Propranolol and fat biopsy",
          "type": "DRUG"
        },
        {
          "name": "heavy water and fat biopsy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Philip Kern",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "35 Years to 60 Years · Female only"
      },
      "enrollment_count": 26,
      "start_date": "2016-03",
      "completion_date": "2018-08-20",
      "has_results": false,
      "last_update_posted_date": "2020-02-07",
      "last_synced_at": "2026-10-21T23:22:59.739Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02596776"
    }
  ]
}