{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Metastatic+Solid+Cancers&page=32", "query": { "condition": "Metastatic Solid Cancers", "page": 32 }, "page_size": 10 }, "pagination": { "page": 32, "page_size": 10, "total_count": 1752, "total_pages": 176, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Metastatic+Solid+Cancers&page=33&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Metastatic+Solid+Cancers&page=31&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-16T09:57:18.601Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00028405", "title": "Photodynamic Therapy System for Patients With Refractory/Unresponsive Solid Tumors", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Liver Metastasis", "Pelvic Cancer", "Head and Neck Cancer", "Sarcoma", "Rectal Cancer", "Breast Cancer", "Colorectal Cancer", "Mouth Cancer" ], "interventions": [ { "name": "LS 11(Taporfin Sodium)", "type": "DRUG" }, { "name": "Lumaflex Light Delivery Catheter", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Light Sciences LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 48, "start_date": "2001-11", "completion_date": "2002-12", "has_results": false, "last_update_posted_date": "2005-06-24", "last_synced_at": "2026-10-16T09:57:18.601Z", "location_count": 6, "location_summary": "Tucson, Arizona • Detroit, Michigan • Greenville, North Carolina + 2 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Greenville", "state": "North Carolina" }, { "city": "Philadelphia", "state": "Pennsylvania" }, { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00028405" }, { "nct_id": "NCT00004988", "title": "Treatment of Patients With Cancer With Genetically Modified Salmonella Typhimurium Bacteria", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Cancer", "Neoplasm", "Neoplasm Metastasis" ], "interventions": [ { "name": "VNP20009", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 45, "start_date": "2000-03", "completion_date": "2002-10", "has_results": false, "last_update_posted_date": "2008-03-04", "last_synced_at": "2026-10-16T09:57:18.601Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00004988" }, { "nct_id": "NCT05215769", "title": "A Video Intervention to Improve Patient Understanding of Tumor Genomic Testing in Patients With Metastatic Cancer", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Anatomic Stage IV Breast Cancer AJCC v8", "Metastatic Breast Carcinoma", "Metastatic Lung Carcinoma", "Metastatic Malignant Solid Neoplasm", "Prognostic Stage IV Breast Cancer AJCC v8", "Stage IV Lung Cancer AJCC v8", "Stage IVA Lung Cancer AJCC v8", "Stage IVB Lung Cancer AJCC v8" ], "interventions": [ { "name": "Health Education", "type": "BEHAVIORAL" }, { "name": "Questionnaire Administration", "type": "OTHER" } ], "intervention_types": [ "BEHAVIORAL", "OTHER" ], "sponsor": "Ohio State University Comprehensive Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 243, "start_date": "2022-03-30", "completion_date": "2026-07-31", "has_results": true, "last_update_posted_date": "2026-04-13", "last_synced_at": "2026-10-16T09:57:18.601Z", "location_count": 4, "location_summary": "Columbus, Ohio • Lima, Ohio • Richmond, Ohio + 1 more", "locations": [ { "city": "Columbus", "state": "Ohio" }, { "city": "Lima", "state": "Ohio" }, { "city": "Richmond", "state": "Ohio" }, { "city": "Youngstown", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT05215769" }, { "nct_id": "NCT07021898", "title": "A Study of ERAS-4001 in Patients With Advanced or Metastatic Solid Tumors.", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Metastatic Solid Tumors" ], "interventions": [ { "name": "ERAS-4001", "type": "DRUG" }, { "name": "ERAS-4001 in combination", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Erasca, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 200, "start_date": "2025-08-06", "completion_date": "2028-12", "has_results": false, "last_update_posted_date": "2025-12-03", "last_synced_at": "2026-10-16T09:57:18.601Z", "location_count": 5, "location_summary": "Nashville, Tennessee • Houston, Texas • Irving, Texas + 2 more", "locations": [ { "city": "Nashville", "state": "Tennessee" }, { "city": "Houston", "state": "Texas" }, { "city": "Irving", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" }, { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT07021898" }, { "nct_id": "NCT06682806", "title": "A Study of PRT3789 in Combination With Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Advanced Solid Tumor", "Esophageal Cancer", "Metastatic Solid Tumor", "Non-small Cell Lung Cancers", "SMARCA4 Gene Mutation" ], "interventions": [ { "name": "PRT3789", "type": "DRUG" }, { "name": "pembrolizumab", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Prelude Therapeutics Incorporated", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 6, "start_date": "2025-06-03", "completion_date": "2026-01-23", "has_results": false, "last_update_posted_date": "2026-02-02", "last_synced_at": "2026-10-16T09:57:18.601Z", "location_count": 6, "location_summary": "West Palm Beach, Florida • Detroit, Michigan • Hackensack, New Jersey + 2 more", "locations": [ { "city": "West Palm Beach", "state": "Florida" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Hackensack", "state": "New Jersey" }, { "city": "Nashville", "state": "Tennessee" }, { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT06682806" }, { "nct_id": "NCT00088101", "title": "STA-5312 Administered on Alternate Weekdays Every Two Weeks to Patients With Hematologic Malignancies and Patients With Solid Tumors", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Hematological Malignancies", "Leukemia", "Lymphoma", "Metastatic or Unresectable Solid Tumors" ], "interventions": [ { "name": "STA-5312", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Synta Pharmaceuticals Corp.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 42, "start_date": "2004-02", "completion_date": "2004-12", "has_results": false, "last_update_posted_date": "2008-12-04", "last_synced_at": "2026-10-16T09:57:18.601Z", "location_count": 8, "location_summary": "Pomona, California • Jacksonville, Florida • Chicago, Illinois + 5 more", "locations": [ { "city": "Pomona", "state": "California" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Newark", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT00088101" }, { "nct_id": "NCT03725436", "title": "ALRN-6924 and Paclitaxel in Treating Patients With Advanced, Metastatic, or Unresectable Solid Tumors", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Advanced Malignant Solid Neoplasm", "Anatomic Stage III Breast Cancer AJCC v8", "Anatomic Stage IIIA Breast Cancer AJCC v8", "Anatomic Stage IIIB Breast Cancer AJCC v8", "Anatomic Stage IIIC Breast Cancer AJCC v8", "Estrogen Receptor Positive", "HER2/Neu Negative", "Metastatic Malignant Solid Neoplasm", "Prognostic Stage III Breast Cancer AJCC v8", "Prognostic Stage IIIA Breast Cancer AJCC v8", "Prognostic Stage IIIB Breast Cancer AJCC v8", "Prognostic Stage IIIC Breast Cancer AJCC v8", "Recurrent Breast Carcinoma", "TP53 wt Allele", "Unresectable Malignant Solid Neoplasm" ], "interventions": [ { "name": "MDM2/MDMX Inhibitor ALRN-6924", "type": "DRUG" }, { "name": "Paclitaxel", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 28, "start_date": "2019-01-24", "completion_date": "2026-03-11", "has_results": false, "last_update_posted_date": "2026-03-16", "last_synced_at": "2026-10-16T09:57:18.601Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03725436" }, { "nct_id": "NCT03954067", "title": "A Study of an Intratumoral Oncolytic Virus in Patients With Advanced Metastatic Solid Tumors", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Metastatic Cancer", "Solid Tumors", "Advanced Cancer" ], "interventions": [ { "name": "ASP9801", "type": "BIOLOGICAL" }, { "name": "Pembrolizumab", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "BIOLOGICAL", "COMBINATION_PRODUCT" ], "sponsor": "Astellas Pharma Global Development, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 72, "start_date": "2019-09-03", "completion_date": "2024-04-19", "has_results": false, "last_update_posted_date": "2025-04-22", "last_synced_at": "2026-10-16T09:57:18.601Z", "location_count": 17, "location_summary": "Birmingham, Alabama • Tucson, Arizona • Los Angeles, California + 14 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Lexington", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT03954067" }, { "nct_id": "NCT00031967", "title": "Melatonin and Radiation Therapy in Treating Patients With Brain Metastases", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Metastatic Cancer", "Radiation Toxicity", "Unspecified Adult Solid Tumor, Protocol Specific" ], "interventions": [ { "name": "therapeutic melatonin", "type": "DRUG" }, { "name": "radiation therapy", "type": "RADIATION" } ], "intervention_types": [ "DRUG", "RADIATION" ], "sponsor": "Radiation Therapy Oncology Group", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "0 Years", "maximum_age": "120 Years", "sex": "ALL", "summary": "0 Years to 120 Years" }, "enrollment_count": null, "start_date": "2002-05", "completion_date": null, "has_results": false, "last_update_posted_date": "2020-10-22", "last_synced_at": "2026-10-16T09:57:18.601Z", "location_count": 215, "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 166 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Montgomery", "state": "Alabama" }, { "city": "Tuscaloosa", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT00031967" }, { "nct_id": "NCT04511845", "title": "A Dose-Escalation Study of SPYK04 in Patients With Locally Advanced or Metastatic Solid Tumors (With Expansion).", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Locally Advanced or Metastatic Solid Tumors" ], "interventions": [ { "name": "SPYK04", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Chugai Pharmaceutical", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 85, "start_date": "2020-09-10", "completion_date": "2026-06-18", "has_results": false, "last_update_posted_date": "2026-07-30", "last_synced_at": "2026-10-16T09:57:18.601Z", "location_count": 9, "location_summary": "Tucson, Arizona • Lone Tree, Colorado • Minneapolis, Minnesota + 6 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Lone Tree", "state": "Colorado" }, { "city": "Minneapolis", "state": "Minnesota" }, { "city": "Providence", "state": "Rhode Island" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04511845" } ] }