{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Microvascular+Function&page=2",
    "query": {
      "condition": "Microvascular Function",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Microvascular+Function&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:18:25.084Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05653973",
      "title": "Prenatal Aspirin and Postpartum Vascular Function",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Preeclampsia",
        "Microvascular Function"
      ],
      "interventions": [
        {
          "name": "Acetylcholine",
          "type": "DRUG"
        },
        {
          "name": "Endothelin-1",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Anna Stanhewicz, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2023-01-03",
      "completion_date": "2027-07-30",
      "has_results": false,
      "last_update_posted_date": "2025-05-31",
      "last_synced_at": "2026-05-22T05:18:25.084Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05653973"
    },
    {
      "nct_id": "NCT02370784",
      "title": "Atorvastatin for Microvascular Endothelial Function and Raynaud in Early Diffuse Scleroderma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Scleroderma"
      ],
      "interventions": [
        {
          "name": "atorvastatin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Robyn T. Domsic, MD, MPH",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 24,
      "start_date": "2015-02",
      "completion_date": "2019-12-15",
      "has_results": true,
      "last_update_posted_date": "2020-08-12",
      "last_synced_at": "2026-05-22T05:18:25.084Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02370784"
    },
    {
      "nct_id": "NCT06043310",
      "title": "Estrogen and Microvascular Function",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Estrogen",
        "Cardiovascular Diseases",
        "Microvasculature",
        "Oral Contraceptive Use"
      ],
      "interventions": [
        {
          "name": "Nω-nitro-L-arginine methyl ester (L-NAME)",
          "type": "DRUG"
        },
        {
          "name": "Acetylcholine",
          "type": "DRUG"
        },
        {
          "name": "Sodium Nitroprusside",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 45,
      "start_date": "2023-10-12",
      "completion_date": "2031-12",
      "has_results": false,
      "last_update_posted_date": "2025-07-04",
      "last_synced_at": "2026-05-22T05:18:25.084Z",
      "location_count": 1,
      "location_summary": "Wauwatosa, Wisconsin",
      "locations": [
        {
          "city": "Wauwatosa",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06043310"
    },
    {
      "nct_id": "NCT05193968",
      "title": "Hot Flashes and Neurovascular Function in Women",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hot Flashes",
        "Menopause",
        "Vasomotor System; Labile"
      ],
      "interventions": [
        {
          "name": "Sympathoexcitatory stressors",
          "type": "OTHER"
        },
        {
          "name": "Sodium Nitroprusside",
          "type": "DRUG"
        },
        {
          "name": "Acetylcholine",
          "type": "DRUG"
        },
        {
          "name": "Terbutaline",
          "type": "DRUG"
        },
        {
          "name": "Norepinephrine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 60 Years · Female only"
      },
      "enrollment_count": 120,
      "start_date": "2022-02-24",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-06-03",
      "last_synced_at": "2026-05-22T05:18:25.084Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05193968"
    },
    {
      "nct_id": "NCT03376555",
      "title": "Cheese Consumption and Human Microvascular Function",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Microvascular Dysfunction"
      ],
      "interventions": [
        {
          "name": "Low sodium no cheese",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Low sodium cheese",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "High sodium no cheese",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "High sodium cheese",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Lacy Alexander",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "55 Years to 75 Years"
      },
      "enrollment_count": 13,
      "start_date": "2017-07-01",
      "completion_date": "2021-03-01",
      "has_results": true,
      "last_update_posted_date": "2025-05-04",
      "last_synced_at": "2026-05-22T05:18:25.084Z",
      "location_count": 1,
      "location_summary": "University Park, Pennsylvania",
      "locations": [
        {
          "city": "University Park",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03376555"
    },
    {
      "nct_id": "NCT05593549",
      "title": "Role of Autophagy in Type 2 Diabetes Microvascular Dysfunction",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Type 2 Diabetes",
        "Healthy Aging"
      ],
      "interventions": [
        {
          "name": "Trehalose",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 60,
      "start_date": "2023-01-01",
      "completion_date": "2029-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-10-30",
      "last_synced_at": "2026-05-22T05:18:25.084Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05593549"
    },
    {
      "nct_id": "NCT00931879",
      "title": "Lovaza® and Microvascular Function in Type 2 Diabetes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Hypertriglyceridemia",
        "Diabetic Neuropathy"
      ],
      "interventions": [
        {
          "name": "omega-3-ethyl esters",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Eastern Virginia Medical School",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 44,
      "start_date": "2009-10",
      "completion_date": "2012-07",
      "has_results": true,
      "last_update_posted_date": "2017-05-09",
      "last_synced_at": "2026-05-22T05:18:25.084Z",
      "location_count": 1,
      "location_summary": "Norfolk, Virginia",
      "locations": [
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00931879"
    },
    {
      "nct_id": "NCT01977417",
      "title": "Inflammation Inhibition in Prediabetic Humans",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Prediabetes",
        "Obese"
      ],
      "interventions": [
        {
          "name": "Salsalate",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Gary L. Pierce",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "18 Years to 79 Years"
      },
      "enrollment_count": 21,
      "start_date": "2012-11",
      "completion_date": "2021-04",
      "has_results": true,
      "last_update_posted_date": "2023-09-11",
      "last_synced_at": "2026-05-22T05:18:25.084Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01977417"
    },
    {
      "nct_id": "NCT00187954",
      "title": "WISE ARIC: Retinal Photography in Women With Chest Pain",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chest Pain"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 75 Years · Female only"
      },
      "enrollment_count": 160,
      "start_date": "2003-06",
      "completion_date": "2014-09",
      "has_results": false,
      "last_update_posted_date": "2021-08-12",
      "last_synced_at": "2026-05-22T05:18:25.084Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00187954"
    },
    {
      "nct_id": "NCT00692991",
      "title": "Using Magnetic Resonance Imaging to Evaluate Heart Vessel Function After Angioplasty or Stent Placement Procedures",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Myocardial Infarction",
        "Angina, Unstable",
        "Cardiomyopathy, Hypertrophic"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 144,
      "start_date": "1999-10",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2016-02-23",
      "last_synced_at": "2026-05-22T05:18:25.084Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00692991"
    }
  ]
}