{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Microvesicle+Particles",
    "query": {
      "condition": "Microvesicle Particles"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 4,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T22:22:58.149Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07640061",
      "title": "Pilot Studies Testing the Use of Oral Amitriptyline in Reducing Localized Burn Injury-induced Microvesicle Particle Release",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Microvesicle Particles",
        "Thermal Burn"
      ],
      "interventions": [
        {
          "name": "Amitriptyline",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wright State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 20,
      "start_date": "2027-06",
      "completion_date": "2033-06",
      "has_results": false,
      "last_update_posted_date": "2026-07-17",
      "last_synced_at": "2026-07-23T22:22:58.149Z",
      "location_count": 1,
      "location_summary": "Fairborn, Ohio",
      "locations": [
        {
          "city": "Fairborn",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07640061"
    },
    {
      "nct_id": "NCT04520217",
      "title": "Testing Use of Topical Imipramine in Reducing Ultraviolet B Induced Microvesicle Particle Release in Photosensitive Subjects",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Photosensitivity",
        "Microvesicle Particle"
      ],
      "interventions": [
        {
          "name": "4% Imipramine Cream",
          "type": "DRUG"
        },
        {
          "name": "Base Cream",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wright State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 40,
      "start_date": "2022-06-06",
      "completion_date": "2026-12-01",
      "has_results": false,
      "last_update_posted_date": "2025-01-27",
      "last_synced_at": "2026-07-23T22:22:58.149Z",
      "location_count": 1,
      "location_summary": "Fairborn, Ohio",
      "locations": [
        {
          "city": "Fairborn",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04520217"
    },
    {
      "nct_id": "NCT03960125",
      "title": "Photodynamic Therapy and Microvesicles",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Photodynamic Therapy",
        "Microvesicle Particle"
      ],
      "interventions": [
        {
          "name": "Photodynamic Therapy",
          "type": "DEVICE"
        },
        {
          "name": "4% Imipramine",
          "type": "DRUG"
        },
        {
          "name": "Base Cream",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Wright State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "21 Years to 45 Years"
      },
      "enrollment_count": 0,
      "start_date": "2021-03-29",
      "completion_date": "2022-09",
      "has_results": false,
      "last_update_posted_date": "2022-09-13",
      "last_synced_at": "2026-07-23T22:22:58.149Z",
      "location_count": 1,
      "location_summary": "Fairborn, Ohio",
      "locations": [
        {
          "city": "Fairborn",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03960125"
    },
    {
      "nct_id": "NCT05734235",
      "title": "UVB-Induced MVP Release in Human Skin",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Ultraviolet B Radiation",
        "Microvesicle Particles"
      ],
      "interventions": [
        {
          "name": "Vitamin C",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Vitamin E",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Wright State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "45 Years",
        "sex": "MALE",
        "summary": "21 Years to 45 Years · Male only"
      },
      "enrollment_count": 8,
      "start_date": "2018-07-16",
      "completion_date": "2022-10-26",
      "has_results": false,
      "last_update_posted_date": "2023-02-24",
      "last_synced_at": "2026-07-23T22:22:58.149Z",
      "location_count": 1,
      "location_summary": "Fairborn, Ohio",
      "locations": [
        {
          "city": "Fairborn",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05734235"
    }
  ]
}