{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Middle+Aged",
    "query": {
      "condition": "Middle Aged"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 135,
    "total_pages": 14,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Middle+Aged&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T07:27:47.238Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00000378",
      "title": "Antidepressant Treatment of Melancholia in Late Life",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Depression",
        "Melancholia"
      ],
      "interventions": [
        {
          "name": "Sertraline",
          "type": "DRUG"
        },
        {
          "name": "Nortriptyline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "New York State Psychiatric Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "60 Years to 95 Years"
      },
      "enrollment_count": 110,
      "start_date": "1997-07",
      "completion_date": "2002-06",
      "has_results": true,
      "last_update_posted_date": "2015-10-07",
      "last_synced_at": "2026-05-22T07:27:47.238Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00000378"
    },
    {
      "nct_id": "NCT04554576",
      "title": "Escoge Salud (Choose Health): a Chronic Pain Self-Management Program in Middle to Older Age Hispanic Americans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Pain"
      ],
      "interventions": [
        {
          "name": "Chronic Disease Self-Management Program (CDSMP) for chronic pain in Spanish",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Remote feedback active group",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Remote feedback control group",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Kaiser Permanente",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "40 Years to 80 Years"
      },
      "enrollment_count": 18,
      "start_date": "2019-02-14",
      "completion_date": "2021-12-31",
      "has_results": false,
      "last_update_posted_date": "2022-05-31",
      "last_synced_at": "2026-05-22T07:27:47.238Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04554576"
    },
    {
      "nct_id": "NCT04530916",
      "title": "Wild Blueberries and Cardiovascular Health in Middle-aged/Older Men and Postmenopausal Women",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Hypertension",
        "Aging",
        "Endothelial Dysfunction",
        "Men"
      ],
      "interventions": [
        {
          "name": "Blueberry Powder",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo Powder",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Colorado State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "70 Years",
        "sex": "MALE",
        "summary": "45 Years to 70 Years · Male only"
      },
      "enrollment_count": 58,
      "start_date": "2020-01-01",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-11-17",
      "last_synced_at": "2026-05-22T07:27:47.238Z",
      "location_count": 1,
      "location_summary": "Fort Collins, Colorado",
      "locations": [
        {
          "city": "Fort Collins",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04530916"
    },
    {
      "nct_id": "NCT07171255",
      "title": "Improving Exercise Adherence With App Technology for At-Risk Adults Living in Rural Kansas and Nebraska",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sedentary Middle Age and Older Aged Adults"
      ],
      "interventions": [
        {
          "name": "RemoteEx+ Programming",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Creighton University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "40 Years to 85 Years"
      },
      "enrollment_count": 54,
      "start_date": "2025-08-22",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-09-12",
      "last_synced_at": "2026-05-22T07:27:47.238Z",
      "location_count": 2,
      "location_summary": "Emporia, Kansas • Omaha, Nebraska",
      "locations": [
        {
          "city": "Emporia",
          "state": "Kansas"
        },
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07171255"
    },
    {
      "nct_id": "NCT04272138",
      "title": "A Brief App-based Mobile Health and Well-being Intervention Among Middle-aged Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Meditation",
        "Control Group"
      ],
      "interventions": [
        {
          "name": "Calm Meditation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Educational Podcast Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Arizona State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "40 Years to 64 Years"
      },
      "enrollment_count": 83,
      "start_date": "2020-02-03",
      "completion_date": "2020-06-16",
      "has_results": false,
      "last_update_posted_date": "2022-02-28",
      "last_synced_at": "2026-05-22T07:27:47.238Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04272138"
    },
    {
      "nct_id": "NCT03803566",
      "title": "Age-independent Decline in Manual Dexterity of Middle-aged and Older Adults",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aging"
      ],
      "interventions": [
        {
          "name": "Pegboard practice",
          "type": "OTHER"
        },
        {
          "name": "Force control practice",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Colorado, Boulder",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "50 Years to 89 Years"
      },
      "enrollment_count": 0,
      "start_date": "2025-08",
      "completion_date": "2026-07",
      "has_results": false,
      "last_update_posted_date": "2021-11-16",
      "last_synced_at": "2026-05-22T07:27:47.238Z",
      "location_count": 1,
      "location_summary": "Boulder, Colorado",
      "locations": [
        {
          "city": "Boulder",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03803566"
    },
    {
      "nct_id": "NCT01143844",
      "title": "Assessing Fertility Potential in Female Cancer Survivors",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Effects of Chemotherapy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "11 Years to 50 Years · Female only"
      },
      "enrollment_count": 391,
      "start_date": "2006-03",
      "completion_date": "2020-03-30",
      "has_results": false,
      "last_update_posted_date": "2021-04-13",
      "last_synced_at": "2026-05-22T07:27:47.238Z",
      "location_count": 2,
      "location_summary": "Philadelphia, Pennsylvania • Radnor, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Radnor",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01143844"
    },
    {
      "nct_id": "NCT05972265",
      "title": "Childhood Trauma, Exercise, and Cognition",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Adverse Childhood Experiences"
      ],
      "interventions": [
        {
          "name": "Moderate Intensity Exercise (one day)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Placebo - Light Intensity Exercise (one day)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Moderate Intensity Exercise (9 wks)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Day 1 Assessments",
          "type": "OTHER"
        },
        {
          "name": "Symptom Measures and Neuropsychological Tests",
          "type": "OTHER"
        },
        {
          "name": "Day 36 Assessments",
          "type": "OTHER"
        },
        {
          "name": "Day 57 Assessments",
          "type": "OTHER"
        },
        {
          "name": "Day 78 Assessments",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Texas at Austin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "40 Years to 60 Years"
      },
      "enrollment_count": 34,
      "start_date": "2023-11-27",
      "completion_date": "2024-12-04",
      "has_results": false,
      "last_update_posted_date": "2023-12-01",
      "last_synced_at": "2026-05-22T07:27:47.238Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05972265"
    },
    {
      "nct_id": "NCT04511065",
      "title": "Computer Based Newsletter and Literacy Engagement of Middle-school Students",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Reading Problem"
      ],
      "interventions": [
        {
          "name": "Newsletter using a virtual mode of delivery",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "State University of New York at Buffalo",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "13 Years",
        "sex": "ALL",
        "summary": "10 Years to 13 Years"
      },
      "enrollment_count": 1,
      "start_date": "2020-10-02",
      "completion_date": "2020-12-14",
      "has_results": false,
      "last_update_posted_date": "2022-06-27",
      "last_synced_at": "2026-05-22T07:27:47.238Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04511065"
    },
    {
      "nct_id": "NCT04660851",
      "title": "Improving Diet Protein Intake in Middle-aged Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dietary Habits"
      ],
      "interventions": [
        {
          "name": "Coached",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Florida Atlantic University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "64 Years",
        "sex": "FEMALE",
        "summary": "45 Years to 64 Years · Female only"
      },
      "enrollment_count": 54,
      "start_date": "2019-06-26",
      "completion_date": "2020-01-24",
      "has_results": false,
      "last_update_posted_date": "2020-12-09",
      "last_synced_at": "2026-05-22T07:27:47.238Z",
      "location_count": 1,
      "location_summary": "Boca Raton, Florida",
      "locations": [
        {
          "city": "Boca Raton",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04660851"
    }
  ]
}