{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Middle+Cerebral+Artery+Stroke",
    "query": {
      "condition": "Middle Cerebral Artery Stroke"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 12,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Middle+Cerebral+Artery+Stroke&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T04:52:22.940Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01429350",
      "title": "Assess the Penumbra System in the Treatment of Acute Stroke",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Ischemic Stroke"
      ],
      "interventions": [
        {
          "name": "intravenous (IV) recombinant human tissue plasminogen activator (rtPA)",
          "type": "DRUG"
        },
        {
          "name": "Penumbra System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Penumbra Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 108,
      "start_date": "2012-05",
      "completion_date": "2016-10",
      "has_results": true,
      "last_update_posted_date": "2020-09-22",
      "last_synced_at": "2026-05-22T04:52:22.940Z",
      "location_count": 4,
      "location_summary": "Denver, Colorado • Gainesville, Florida • Chicago, Illinois + 1 more",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01429350"
    },
    {
      "nct_id": "NCT01310114",
      "title": "Study of Human Placenta-derived Cells (PDA001) to Evaluate the Safety and Effectiveness for Patients With Ischemic Stroke",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Stroke, Acute",
        "Middle Cerebral Artery Stroke",
        "Posterior Cerebral Artery Stroke"
      ],
      "interventions": [
        {
          "name": "Human Placenta-Derived Cells PDA001- (cenplacel-L)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG"
      ],
      "sponsor": "Celularity Incorporated",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 44,
      "start_date": "2011-03",
      "completion_date": "2013-03",
      "has_results": false,
      "last_update_posted_date": "2018-03-01",
      "last_synced_at": "2026-05-22T04:52:22.940Z",
      "location_count": 1,
      "location_summary": "Chattanooga, Tennessee",
      "locations": [
        {
          "city": "Chattanooga",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01310114"
    },
    {
      "nct_id": "NCT04156490",
      "title": "Osmotic Agent Use in Middle Cerebral Artery Stroke",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ischemic Stroke",
        "MCA Infarction"
      ],
      "interventions": [
        {
          "name": "No intervention is planned, this will be a purely retrospective trial.",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 100,
      "start_date": "2018-02-10",
      "completion_date": "2019-06-30",
      "has_results": false,
      "last_update_posted_date": "2019-11-07",
      "last_synced_at": "2026-05-22T04:52:22.940Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04156490"
    },
    {
      "nct_id": "NCT02875938",
      "title": "Effect of Music on Reading Comprehension for Patients With Aphasia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aphasia"
      ],
      "interventions": [
        {
          "name": "Simultaneous music and reading lyrics",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Priming with music",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Carilion Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1,
      "start_date": "2016-07",
      "completion_date": "2017-08",
      "has_results": false,
      "last_update_posted_date": "2019-09-20",
      "last_synced_at": "2026-05-22T04:52:22.940Z",
      "location_count": 1,
      "location_summary": "Rocky Mount, Virginia",
      "locations": [
        {
          "city": "Rocky Mount",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02875938"
    },
    {
      "nct_id": "NCT03600987",
      "title": "Effect of Music on Reading Comprehension in Patients With Aphasia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aphasia"
      ],
      "interventions": [
        {
          "name": "Simultaneous music and reading lyrics",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Priming with music",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Carilion Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4,
      "start_date": "2017-10-18",
      "completion_date": "2019-10-17",
      "has_results": false,
      "last_update_posted_date": "2020-01-06",
      "last_synced_at": "2026-05-22T04:52:22.940Z",
      "location_count": 1,
      "location_summary": "Rocky Mount, Virginia",
      "locations": [
        {
          "city": "Rocky Mount",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03600987"
    },
    {
      "nct_id": "NCT04292600",
      "title": "Testing of Identification Markers for Stroke",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Stroke, Ischemic",
        "Infarction, Middle Cerebral Artery",
        "Infarction, Anterior Circulation, Brain"
      ],
      "interventions": [
        {
          "name": "POCKiT diagnostics' algorithm for LVO detection",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "POCKiT diagnostics Ltd",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 383,
      "start_date": "2021-05-01",
      "completion_date": "2023-01-31",
      "has_results": false,
      "last_update_posted_date": "2023-04-03",
      "last_synced_at": "2026-05-22T04:52:22.940Z",
      "location_count": 3,
      "location_summary": "Birmingham, Alabama • Brandon, Florida • Jackson, Mississippi",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Brandon",
          "state": "Florida"
        },
        {
          "city": "Jackson",
          "state": "Mississippi"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04292600"
    },
    {
      "nct_id": "NCT03086551",
      "title": "Modulating Interaction of Motor Learning Networks in Rehabilitation of Stroke",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stroke",
        "Stroke, Chronic",
        "Stroke, Middle Cerebral Artery With Infarction"
      ],
      "interventions": [
        {
          "name": "Active continuous theta burst stimulation (cTBS)",
          "type": "DEVICE"
        },
        {
          "name": "Placebo (Sham) continuous theta burst stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Motor Practice",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "50 Years to 75 Years"
      },
      "enrollment_count": 12,
      "start_date": "2016-04-01",
      "completion_date": "2019-03-30",
      "has_results": true,
      "last_update_posted_date": "2020-04-27",
      "last_synced_at": "2026-05-22T04:52:22.940Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03086551"
    },
    {
      "nct_id": "NCT07584681",
      "title": "Connectomic Alterations Following Acute Ischemic Stroke in the MCA Territory",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ischemic Stroke"
      ],
      "interventions": [
        {
          "name": "MRI with connectomic sequencing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Northwell Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2026-05",
      "completion_date": "2028-04",
      "has_results": false,
      "last_update_posted_date": "2026-05-13",
      "last_synced_at": "2026-05-22T04:52:22.940Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07584681"
    },
    {
      "nct_id": "NCT01273337",
      "title": "Study of ALD-401 Via Intracarotid Infusion in Ischemic Stroke Subjects",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Stroke",
        "Ischemic Stroke",
        "Stroke in Middle Cerebral Artery (MCA)"
      ],
      "interventions": [
        {
          "name": "ALD-401",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Sham Procedure",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "PROCEDURE"
      ],
      "sponsor": "Aldagen",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "83 Years",
        "sex": "ALL",
        "summary": "30 Years to 83 Years"
      },
      "enrollment_count": 100,
      "start_date": "2011-03",
      "completion_date": "2015-01",
      "has_results": false,
      "last_update_posted_date": "2014-01-16",
      "last_synced_at": "2026-05-22T04:52:22.940Z",
      "location_count": 9,
      "location_summary": "Los Angeles, California • Miami, Florida • Minneapolis, Minnesota + 6 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01273337"
    },
    {
      "nct_id": "NCT07053917",
      "title": "Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Stroke",
        "Chronic Stroke",
        "Intracerebral Haemorrhage",
        "Intracerebral Haemorrhage (ICH)",
        "Intracerebral Hemorrhage Basal Ganglia",
        "Ischemic Stroke",
        "Ischemic Stroke and Hemorrhagic Stroke",
        "Hemiparesis After Stroke",
        "Hemiplegia Following Ischemic Stroke",
        "Hemiplegia and Hemiparesis",
        "Hemiplegia and/or Hemiparesis Following Stroke",
        "Middle Cerebral Artery Stroke"
      ],
      "interventions": [
        {
          "name": "Psilocybin (Usona Institute)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2026-02-09",
      "completion_date": "2027-03",
      "has_results": false,
      "last_update_posted_date": "2026-02-13",
      "last_synced_at": "2026-05-22T04:52:22.940Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07053917"
    }
  ]
}