{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Middle-ear+Function",
    "query": {
      "condition": "Middle-ear Function"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 11,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Middle-ear+Function&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T12:41:28.055Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01955486",
      "title": "Gas Supply, Demand and Middle Ear Gas Balance -- Preliminary Protocol",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Middle-ear Function"
      ],
      "interventions": [
        {
          "name": "flight simulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 2,
      "start_date": "2013-10",
      "completion_date": "2018-04-03",
      "has_results": false,
      "last_update_posted_date": "2019-08-07",
      "last_synced_at": "2026-06-10T12:41:28.055Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01955486"
    },
    {
      "nct_id": "NCT02019888",
      "title": "Wide Frequency Band Test of Hearing in Veterans",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hearing Loss, Sensorineural",
        "Hearing Loss, Conductive",
        "Hearing Loss, Mixed Conductive-Sensorineural",
        "Otosclerosis",
        "Tympanic Membrane Perforation",
        "Otitis Media With Effusion",
        "Cholesteatoma"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "20 Years to 89 Years"
      },
      "enrollment_count": 320,
      "start_date": "2014-12-01",
      "completion_date": "2020-01-31",
      "has_results": true,
      "last_update_posted_date": "2021-04-08",
      "last_synced_at": "2026-06-10T12:41:28.055Z",
      "location_count": 2,
      "location_summary": "Portland, Oregon • Mountain Home, Tennessee",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Mountain Home",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02019888"
    },
    {
      "nct_id": "NCT00422929",
      "title": "Eustachian Tube Growth and Development",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Otitis Media"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "3 Years",
        "sex": "ALL",
        "summary": "3 Years to 3 Years"
      },
      "enrollment_count": 126,
      "start_date": "2006-08",
      "completion_date": "2018-08-24",
      "has_results": false,
      "last_update_posted_date": "2019-02-22",
      "last_synced_at": "2026-06-10T12:41:28.055Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00422929"
    },
    {
      "nct_id": "NCT01925495",
      "title": "Gas Supply, Demand and Middle Ear Gas Balance: Specific Aim 3",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Middle-ear Function"
      ],
      "interventions": [
        {
          "name": "varied middle-ear pressure",
          "type": "OTHER"
        },
        {
          "name": "varied middle-ear gas composition",
          "type": "DRUG"
        },
        {
          "name": "varied ear-canal pressure",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "Cuneyt M. Alper",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 32,
      "start_date": "2016-12-02",
      "completion_date": "2019-01-17",
      "has_results": false,
      "last_update_posted_date": "2019-05-17",
      "last_synced_at": "2026-06-10T12:41:28.055Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01925495"
    },
    {
      "nct_id": "NCT01932736",
      "title": "Functional Manifestations of Pressure Changes in the Middle Ear System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Middle-ear Function"
      ],
      "interventions": [
        {
          "name": "changing ear canal pressure",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "21 Years to 35 Years"
      },
      "enrollment_count": 5,
      "start_date": "2013-08",
      "completion_date": "2016-04",
      "has_results": false,
      "last_update_posted_date": "2016-06-20",
      "last_synced_at": "2026-06-10T12:41:28.055Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01932736"
    },
    {
      "nct_id": "NCT03511417",
      "title": "The Effectiveness of Over the Counter Hearing Products for Middle-Aged Adults",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hearing Loss, Functional"
      ],
      "interventions": [
        {
          "name": "over-the-counter hearing device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Massachusetts, Amherst",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "40 Years to 64 Years"
      },
      "enrollment_count": 0,
      "start_date": "2018-10-16",
      "completion_date": "2020-01-17",
      "has_results": false,
      "last_update_posted_date": "2021-10-20",
      "last_synced_at": "2026-06-10T12:41:28.055Z",
      "location_count": 1,
      "location_summary": "Amherst, Massachusetts",
      "locations": [
        {
          "city": "Amherst",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03511417"
    },
    {
      "nct_id": "NCT03868891",
      "title": "Exercises for Improving Soft Palate and Eustachian Tube Function in Children With Ear Tubes With or Without Cleft Palate",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cleft Palate",
        "Tube Disorders Eustachian",
        "Velopharyngeal Incompetence Due to Cleft Palate",
        "Velopharyngeal Insufficiency"
      ],
      "interventions": [
        {
          "name": "EMST150",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Noel Jabbour",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "6 Years to 17 Years"
      },
      "enrollment_count": 11,
      "start_date": "2019-08-16",
      "completion_date": "2022-05-31",
      "has_results": true,
      "last_update_posted_date": "2023-06-23",
      "last_synced_at": "2026-06-10T12:41:28.055Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03868891"
    },
    {
      "nct_id": "NCT00423072",
      "title": "Middle Ear Pressure Disregulation in Cleft Palate Patients",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cleft Palate"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "24 Months",
        "sex": "ALL",
        "summary": "Up to 24 Months"
      },
      "enrollment_count": 82,
      "start_date": "2006-08",
      "completion_date": "2017-05-22",
      "has_results": false,
      "last_update_posted_date": "2019-02-18",
      "last_synced_at": "2026-06-10T12:41:28.055Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00423072"
    },
    {
      "nct_id": "NCT01974726",
      "title": "Gas Supply, Demand and Middle Ear Gas Balance -- Diagnosis of Eustachian Tube Dysfunction",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Eustachian Tube Dysfunction"
      ],
      "interventions": [
        {
          "name": "ET Stress test",
          "type": "OTHER"
        },
        {
          "name": "Sonotubometry",
          "type": "OTHER"
        },
        {
          "name": "Forced Response Test (FRT)",
          "type": "OTHER"
        },
        {
          "name": "Inflation Deflation Test (IDT)",
          "type": "OTHER"
        },
        {
          "name": "Maneuver Sequence",
          "type": "OTHER"
        },
        {
          "name": "9-Step Test",
          "type": "OTHER"
        },
        {
          "name": "Tubomanometry",
          "type": "OTHER"
        },
        {
          "name": "Videoendoscopic assessment of ETF",
          "type": "OTHER"
        },
        {
          "name": "Pressure chamber ET test",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "3 Years to 70 Years"
      },
      "enrollment_count": 95,
      "start_date": "2013-10",
      "completion_date": "2019-06-27",
      "has_results": false,
      "last_update_posted_date": "2020-10-08",
      "last_synced_at": "2026-06-10T12:41:28.055Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01974726"
    },
    {
      "nct_id": "NCT00393900",
      "title": "Middle Ear Pressure Disregulation After Tympanostomy Tube Insertion",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Otitis Media With Effusion"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "6 Years",
        "sex": "ALL",
        "summary": "3 Years to 6 Years"
      },
      "enrollment_count": 84,
      "start_date": "2006-08",
      "completion_date": "2012-10",
      "has_results": false,
      "last_update_posted_date": "2017-10-19",
      "last_synced_at": "2026-06-10T12:41:28.055Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00393900"
    }
  ]
}