{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Midlife+Adults&page=2",
    "query": {
      "condition": "Midlife Adults",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Midlife+Adults&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T09:21:27.490Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05300971",
      "title": "Passive Heat Therapy for Lowering Systolic Blood Pressure and Improving Vascular Function in Mid-life and Older Adults",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aging"
      ],
      "interventions": [
        {
          "name": "Heat therapy",
          "type": "OTHER"
        },
        {
          "name": "Thermoneutral water immersion",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Colorado, Boulder",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2022-08-01",
      "completion_date": "2028-02-01",
      "has_results": false,
      "last_update_posted_date": "2025-04-29",
      "last_synced_at": "2026-07-23T09:21:27.490Z",
      "location_count": 1,
      "location_summary": "Boulder, Colorado",
      "locations": [
        {
          "city": "Boulder",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05300971"
    },
    {
      "nct_id": "NCT05211726",
      "title": "The Effects of Added Sugar Intake on Brain Blood Flow and Hippocampal Function in Midlife Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aging",
        "Healthy Diet"
      ],
      "interventions": [
        {
          "name": "Low Added Sugar Diet",
          "type": "OTHER"
        },
        {
          "name": "High Added Sugar Diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Delaware",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "50 Years to 64 Years"
      },
      "enrollment_count": 44,
      "start_date": "2022-01-11",
      "completion_date": "2024-05-03",
      "has_results": true,
      "last_update_posted_date": "2025-06-12",
      "last_synced_at": "2026-07-23T09:21:27.490Z",
      "location_count": 1,
      "location_summary": "Newark, Delaware",
      "locations": [
        {
          "city": "Newark",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05211726"
    },
    {
      "nct_id": "NCT03272438",
      "title": "Schedule Intervention to Increase Sustainable Walking Activity in Midlife Working Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Physical Activity"
      ],
      "interventions": [
        {
          "name": "Accelerometer",
          "type": "DEVICE"
        },
        {
          "name": "Step goal",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Consistent contexts",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Inconsistent contexts",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "Brandeis University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "40 Years to 65 Years"
      },
      "enrollment_count": 149,
      "start_date": "2018-04-13",
      "completion_date": "2019-07-24",
      "has_results": false,
      "last_update_posted_date": "2025-02-17",
      "last_synced_at": "2026-07-23T09:21:27.490Z",
      "location_count": 1,
      "location_summary": "Waltham, Massachusetts",
      "locations": [
        {
          "city": "Waltham",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03272438"
    },
    {
      "nct_id": "NCT06434038",
      "title": "Measurement of Insulin Levels in the Cerebrospinal Fluid of Healthy Adults After a Single Intranasal Dose - Middle Age",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Low Dose Regular insulin",
          "type": "DRUG"
        },
        {
          "name": "High Dose Regular insulin",
          "type": "DRUG"
        },
        {
          "name": "0.9% Saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "HealthPartners Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "36 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "36 Years to 55 Years"
      },
      "enrollment_count": 0,
      "start_date": "2025-08-30",
      "completion_date": "2026-02-28",
      "has_results": false,
      "last_update_posted_date": "2025-11-25",
      "last_synced_at": "2026-07-23T09:21:27.490Z",
      "location_count": 1,
      "location_summary": "Saint Paul, Minnesota",
      "locations": [
        {
          "city": "Saint Paul",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06434038"
    },
    {
      "nct_id": "NCT05986604",
      "title": "NIA_Improving Function and Well-being by Improving Patient Memory: Transdiagnostic Sleep and Circadian Treatment",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep Disorder",
        "Circadian Dysregulation",
        "Memory Impairment"
      ],
      "interventions": [
        {
          "name": "Memory Support Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Transdiagnostic Intervention for Sleep and Circadian Dysfunction",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, Berkeley",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 178,
      "start_date": "2024-01-04",
      "completion_date": "2028-07-28",
      "has_results": false,
      "last_update_posted_date": "2025-11-24",
      "last_synced_at": "2026-07-23T09:21:27.490Z",
      "location_count": 1,
      "location_summary": "Berkeley, California",
      "locations": [
        {
          "city": "Berkeley",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05986604"
    },
    {
      "nct_id": "NCT04911491",
      "title": "Inspiratory Muscle Strength Training in Chronic Kidney Disease",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Kidney Diseases",
        "Hypertension",
        "Aging",
        "Blood Pressure"
      ],
      "interventions": [
        {
          "name": "IMST",
          "type": "DEVICE"
        },
        {
          "name": "Sham Training",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 108,
      "start_date": "2022-03-01",
      "completion_date": "2026-07-01",
      "has_results": false,
      "last_update_posted_date": "2025-05-02",
      "last_synced_at": "2026-07-23T09:21:27.490Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04911491"
    },
    {
      "nct_id": "NCT05388318",
      "title": "Weight Reduction and Cognitive Health: Pilot Study Testing a Prolonged Testing Prolonged Fasting Among Obese, Stressed Mid-life Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Midlife Obese Adults With Cognitive Decline"
      ],
      "interventions": [
        {
          "name": "Prolonged nightly fasting",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Health Education Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Arizona State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "59 Years",
        "sex": "ALL",
        "summary": "40 Years to 59 Years"
      },
      "enrollment_count": 49,
      "start_date": "2022-03-17",
      "completion_date": "2023-08-31",
      "has_results": false,
      "last_update_posted_date": "2024-01-29",
      "last_synced_at": "2026-07-23T09:21:27.490Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05388318"
    },
    {
      "nct_id": "NCT04745182",
      "title": "A Tailored Program to Promote Well-being and Physical Activity in Mid-life Adults With Low Physical Activity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Middle Aged",
        "Exercise"
      ],
      "interventions": [
        {
          "name": "MASTERY",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "45 Years to 64 Years"
      },
      "enrollment_count": 11,
      "start_date": "2019-10-01",
      "completion_date": "2020-03-19",
      "has_results": false,
      "last_update_posted_date": "2021-02-09",
      "last_synced_at": "2026-07-23T09:21:27.490Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04745182"
    },
    {
      "nct_id": "NCT01499706",
      "title": "Telephone-delivered Behavioral Interventions to Reduce Risky Sexual Behavior in HIV-positive Late Middle-age and Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Unsafe Sex"
      ],
      "interventions": [
        {
          "name": "1-session of telephone-administered motivational interviewing",
          "type": "BEHAVIORAL"
        },
        {
          "name": "4-session telephone-administered motivational interviewing",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Ohio University College of Osteopathic Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "45 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2009-11",
      "completion_date": "2010-10",
      "has_results": false,
      "last_update_posted_date": "2011-12-26",
      "last_synced_at": "2026-07-23T09:21:27.490Z",
      "location_count": 1,
      "location_summary": "Athens, Ohio",
      "locations": [
        {
          "city": "Athens",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01499706"
    },
    {
      "nct_id": "NCT05980052",
      "title": "Goal Setting to Promote Physical Activity Adherence in Midlife Adults",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Physical Activity",
        "Exercise"
      ],
      "interventions": [
        {
          "name": "Physical Activity",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Arizona State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "45 Years to 65 Years"
      },
      "enrollment_count": 144,
      "start_date": "2023-07-17",
      "completion_date": "2027-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-17",
      "last_synced_at": "2026-07-23T09:21:27.490Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05980052"
    }
  ]
}