{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Migraine+With+Aura&page=2",
    "query": {
      "condition": "Migraine With Aura",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Migraine+With+Aura&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T08:16:24.192Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04936061",
      "title": "Transnasal Cooling for Migraine",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Migraine",
        "Episodic Migraine",
        "Migraine With Aura",
        "Migraine Without Aura"
      ],
      "interventions": [
        {
          "name": "CoolStat active device",
          "type": "DEVICE"
        },
        {
          "name": "CoolStat sham device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CoolTech LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 24,
      "start_date": "2021-10-14",
      "completion_date": "2022-09-30",
      "has_results": true,
      "last_update_posted_date": "2023-09-29",
      "last_synced_at": "2026-05-22T08:16:24.192Z",
      "location_count": 3,
      "location_summary": "Scottsdale, Arizona • East Lansing, Michigan • Charlotte, North Carolina",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "East Lansing",
          "state": "Michigan"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04936061"
    },
    {
      "nct_id": "NCT00471952",
      "title": "Maxalt 10mg Plus Caffeine 75mg in the Acute Treatment of Migraine Headache",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Migraine With Aura",
        "Migraine Without Aura"
      ],
      "interventions": [
        {
          "name": "Maxalt 10mg MLT plus Caffeine 75mg",
          "type": "DRUG"
        },
        {
          "name": "Maxalt 10mg MLT plus Placebo",
          "type": "DRUG"
        },
        {
          "name": "Placebo + Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Diamond Headache Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 50,
      "start_date": "2007-04",
      "completion_date": "2008-04",
      "has_results": false,
      "last_update_posted_date": "2012-04-25",
      "last_synced_at": "2026-05-22T08:16:24.192Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00471952"
    },
    {
      "nct_id": "NCT03874832",
      "title": "A Phase I Study to Study the PK and Safety of Single Doses of STS101, DHE Injection and Nasal Spray in Healthy Subjects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Migraine With Aura",
        "Migraine Without Aura",
        "Migraine"
      ],
      "interventions": [
        {
          "name": "Dihydroergotamine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Satsuma Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 46,
      "start_date": "2018-09-11",
      "completion_date": "2018-11-07",
      "has_results": false,
      "last_update_posted_date": "2019-11-26",
      "last_synced_at": "2026-05-22T08:16:24.192Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03874832"
    },
    {
      "nct_id": "NCT03877718",
      "title": "A Study to Assess the Efficacy and Safety of Oral CL-H1T in the Treatment of Acute Migraine Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Migraine",
        "Pain",
        "Nausea",
        "Vomiting",
        "Aura"
      ],
      "interventions": [
        {
          "name": "Arm 1: CL-H1T",
          "type": "DRUG"
        },
        {
          "name": "Arm 2: CL-H1T",
          "type": "DRUG"
        },
        {
          "name": "Arm 3: Sumatriptan Succinate 100 mg capsule",
          "type": "DRUG"
        },
        {
          "name": "Arm 4: Promethazine HCl 18.75 mg",
          "type": "DRUG"
        },
        {
          "name": "Arm 5: Promethazine HCl 37.5 mg",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Charleston Laboratories, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 475,
      "start_date": "2019-02-01",
      "completion_date": "2019-08-27",
      "has_results": false,
      "last_update_posted_date": "2019-11-01",
      "last_synced_at": "2026-05-22T08:16:24.192Z",
      "location_count": 3,
      "location_summary": "New Port Richey, Florida • North Miami Beach, Florida • Greer, South Carolina",
      "locations": [
        {
          "city": "New Port Richey",
          "state": "Florida"
        },
        {
          "city": "North Miami Beach",
          "state": "Florida"
        },
        {
          "city": "Greer",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03877718"
    },
    {
      "nct_id": "NCT04100135",
      "title": "GORE® CARDIOFORM Septal Occluder Migraine Clinical Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Migraine",
        "Patent Foramen Ovale",
        "PFO - Patent Foramen Ovale"
      ],
      "interventions": [
        {
          "name": "Actual device PFO closure",
          "type": "DEVICE"
        },
        {
          "name": "Thienopyridine (clopidogrel or prasugrel)",
          "type": "DRUG"
        },
        {
          "name": "Sham device PFO closure",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "W.L.Gore & Associates",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 7,
      "start_date": "2021-02-05",
      "completion_date": "2024-08-15",
      "has_results": false,
      "last_update_posted_date": "2024-12-18",
      "last_synced_at": "2026-05-22T08:16:24.192Z",
      "location_count": 15,
      "location_summary": "Phoenix, Arizona • Los Angeles, California • Santa Barbara, California + 11 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Santa Barbara",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Loveland",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04100135"
    },
    {
      "nct_id": "NCT01720862",
      "title": "Migraine and Body Composition",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Migraine With and Without Aura",
        "Chronic Migraine",
        "Healthy Controls"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 300,
      "start_date": "2012-04",
      "completion_date": "2015-10",
      "has_results": false,
      "last_update_posted_date": "2016-01-28",
      "last_synced_at": "2026-05-22T08:16:24.192Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01720862"
    },
    {
      "nct_id": "NCT02287376",
      "title": "Pharmacokinetics & Safety of Cambia® in Migraine With or Without Aura in 12-17 Year Olds",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Migraine"
      ],
      "interventions": [
        {
          "name": "Diclofenac Potassium for Oral Solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Depomed",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "12 Years to 17 Years"
      },
      "enrollment_count": 25,
      "start_date": "2015-01",
      "completion_date": "2016-02",
      "has_results": true,
      "last_update_posted_date": "2017-07-25",
      "last_synced_at": "2026-05-22T08:16:24.192Z",
      "location_count": 2,
      "location_summary": "Tampa, Florida • Amherst, New York",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Amherst",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02287376"
    },
    {
      "nct_id": "NCT00203216",
      "title": "A Clinical Study Examining the Safety and Effectiveness of a New Medication (Keppra®) for the Prevention of Migraine Headaches",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Migraine"
      ],
      "interventions": [
        {
          "name": "levetiracetam",
          "type": "DRUG"
        },
        {
          "name": "Transcranial Magnetic Stimulation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 31,
      "start_date": "2002-09",
      "completion_date": "2005-09",
      "has_results": true,
      "last_update_posted_date": "2011-08-11",
      "last_synced_at": "2026-05-22T08:16:24.192Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00203216"
    },
    {
      "nct_id": "NCT00158002",
      "title": "A Study of Topiramate in Pediatric Subjects With Basilar/Hemiplegic Migraine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Basilar Migraine"
      ],
      "interventions": [
        {
          "name": "Topiramate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Monarch Medical Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "6 Years to 18 Years"
      },
      "enrollment_count": 40,
      "start_date": "2004-02",
      "completion_date": "2006-08",
      "has_results": false,
      "last_update_posted_date": "2007-04-05",
      "last_synced_at": "2026-05-22T08:16:24.192Z",
      "location_count": 1,
      "location_summary": "Norfolk, Virginia",
      "locations": [
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00158002"
    },
    {
      "nct_id": "NCT03338920",
      "title": "Study to Assess the Safety and Efficacy of ONZETRA® Xsail® for the Acute Treatment of Episodic Migraine With or Without Aura in Adolescents",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Acute Migraine With or Without Aura"
      ],
      "interventions": [
        {
          "name": "sumatriptan nasal powder",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Currax Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "12 Years to 17 Years"
      },
      "enrollment_count": 159,
      "start_date": "2017-11-02",
      "completion_date": "2022-04-11",
      "has_results": true,
      "last_update_posted_date": "2023-07-24",
      "last_synced_at": "2026-05-22T08:16:24.192Z",
      "location_count": 40,
      "location_summary": "Phoenix, Arizona • Anaheim, California • Los Angeles, California + 33 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03338920"
    }
  ]
}