{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Mild+Depression&page=2",
    "query": {
      "condition": "Mild Depression",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Mild+Depression&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T07:07:12.227Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05462977",
      "title": "Rhythmically Entrained Exercise in Community-Dwelling Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Exercise",
        "Gait",
        "Cognitive Decline",
        "Caregiver Burden",
        "Cognitive Impairment",
        "Dementia",
        "Alzheimer Disease",
        "Mild Cognitive Impairment",
        "Respite Care",
        "Mental Health",
        "Depression",
        "Music Therapy",
        "Psychosocial Intervention",
        "Cognition",
        "Geriatric Assessment",
        "Cognitive Dysfunction",
        "Cognitive Aging",
        "Outcome Assessment, Health Care",
        "Balance",
        "Fall",
        "Walking",
        "Affect",
        "Physical Exertion",
        "Memory Deficit",
        "Memory Disorders",
        "Memory Impairment",
        "Neuropsychological Tests",
        "Executive Function",
        "Middle Aged",
        "Healthy Aging",
        "Elderly"
      ],
      "interventions": [
        {
          "name": "Group exercise program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Greensboro",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "55 Years to 99 Years"
      },
      "enrollment_count": 18,
      "start_date": "2022-05-01",
      "completion_date": "2023-09-30",
      "has_results": false,
      "last_update_posted_date": "2023-11-02",
      "last_synced_at": "2026-06-11T07:07:12.227Z",
      "location_count": 1,
      "location_summary": "Greensboro, North Carolina",
      "locations": [
        {
          "city": "Greensboro",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05462977"
    },
    {
      "nct_id": "NCT01876823",
      "title": "Memantine Plus Es-citalopram in Elderly Depressed Patients With Cognitive Impairment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Mild Cognitive Impairment",
        "Major Depressive Disorder",
        "Alzheimer's Disease"
      ],
      "interventions": [
        {
          "name": "es-citalopram",
          "type": "DRUG"
        },
        {
          "name": "Memantine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "New York State Psychiatric Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "50 Years to 90 Years"
      },
      "enrollment_count": 60,
      "start_date": "2006-04",
      "completion_date": "2010-03",
      "has_results": true,
      "last_update_posted_date": "2014-10-24",
      "last_synced_at": "2026-06-11T07:07:12.227Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01876823"
    },
    {
      "nct_id": "NCT05531591",
      "title": "RCT of Brain Longitudinal Biomarker Study (OPT-Neuro RCT)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Depression",
        "Dementia",
        "Mild Cognitive Impairment",
        "Treatment Resistant Depression",
        "Major Depressive Disorder",
        "Treatment-Refractory Depression",
        "Late Life Depression",
        "Geriatric Depression"
      ],
      "interventions": [
        {
          "name": "Aripiprazole Augmentation",
          "type": "DRUG"
        },
        {
          "name": "Bupropion Augmentation",
          "type": "DRUG"
        },
        {
          "name": "Switch to bupropion",
          "type": "DRUG"
        },
        {
          "name": "Lithium Augmentation",
          "type": "DRUG"
        },
        {
          "name": "Switch to nortriptyline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Centre for Addiction and Mental Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 87,
      "start_date": "2019-08-01",
      "completion_date": "2024-07-31",
      "has_results": false,
      "last_update_posted_date": "2024-11-25",
      "last_synced_at": "2026-06-11T07:07:12.227Z",
      "location_count": 3,
      "location_summary": "Los Angeles, California • St Louis, Missouri • New York, New York",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05531591"
    },
    {
      "nct_id": "NCT01831362",
      "title": "Dismantling Mindfulness: Contributions of Attention vs. Acceptance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mild-moderate Unipolar Depression; Persistent Negative Affect"
      ],
      "interventions": [
        {
          "name": "Mindfulness-Based Cognitive Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Focused Attention (FA)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Open- Monitoring",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Brown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 104,
      "start_date": "2013-02",
      "completion_date": "2016-03-15",
      "has_results": false,
      "last_update_posted_date": "2018-11-05",
      "last_synced_at": "2026-06-11T07:07:12.227Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01831362"
    },
    {
      "nct_id": "NCT03254342",
      "title": "MRS and Medication Response: A Pilot Study",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Major Depressive Disorder",
        "Major Depressive Episode",
        "Major Depressive Disorder, Recurrent",
        "Major Depression Mild",
        "Major Depression Moderate",
        "Major Depression Severe"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 3,
      "start_date": "2013-08-06",
      "completion_date": "2020-08-31",
      "has_results": false,
      "last_update_posted_date": "2021-08-19",
      "last_synced_at": "2026-06-11T07:07:12.227Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03254342"
    },
    {
      "nct_id": "NCT02307617",
      "title": "Glutamate Probes in Adolescent Depression",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Major Depressive Disorder",
        "Major Depressive Disorder, Recurrent",
        "Major Depressive Disorder, Remitted"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "13 Years to 21 Years"
      },
      "enrollment_count": 57,
      "start_date": "2014-08-01",
      "completion_date": "2017-04-17",
      "has_results": false,
      "last_update_posted_date": "2021-04-23",
      "last_synced_at": "2026-06-11T07:07:12.227Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02307617"
    },
    {
      "nct_id": "NCT05708222",
      "title": "Sleep Signal Analysis for Current Major Depressive Episode (SAMDE)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Depressive Episode",
        "Depression",
        "Depressive Disorder",
        "Depressive Disorder, Major",
        "Depression Mild"
      ],
      "interventions": [
        {
          "name": "MEB-001",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medibio Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "22 Years to 75 Years"
      },
      "enrollment_count": 715,
      "start_date": "2022-09-01",
      "completion_date": "2024-07-09",
      "has_results": false,
      "last_update_posted_date": "2024-07-11",
      "last_synced_at": "2026-06-11T07:07:12.227Z",
      "location_count": 13,
      "location_summary": "Bradenton, Florida • Blaine, Minnesota • Plymouth, Minnesota + 10 more",
      "locations": [
        {
          "city": "Bradenton",
          "state": "Florida"
        },
        {
          "city": "Blaine",
          "state": "Minnesota"
        },
        {
          "city": "Plymouth",
          "state": "Minnesota"
        },
        {
          "city": "Clayton",
          "state": "North Carolina"
        },
        {
          "city": "Raleigh",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05708222"
    },
    {
      "nct_id": "NCT00151294",
      "title": "The Efficacy and Safety of Escitalopram for Depression in Multiple Sclerosis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Depression",
        "Multiple Sclerosis"
      ],
      "interventions": [
        {
          "name": "escitalopram oxalate antidepressant",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2004-11",
      "completion_date": "2006-10",
      "has_results": false,
      "last_update_posted_date": "2006-09-14",
      "last_synced_at": "2026-06-11T07:07:12.227Z",
      "location_count": 1,
      "location_summary": "White Plains, New York",
      "locations": [
        {
          "city": "White Plains",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00151294"
    },
    {
      "nct_id": "NCT01886586",
      "title": "Retaining Cognition While Avoiding Late-Life Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mild Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "Problem Solving Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Problem Solving Therapy + Exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enhanced Usual Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 94,
      "start_date": "2011-07",
      "completion_date": "2016-07",
      "has_results": false,
      "last_update_posted_date": "2017-11-14",
      "last_synced_at": "2026-06-11T07:07:12.227Z",
      "location_count": 2,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01886586"
    },
    {
      "nct_id": "NCT02655354",
      "title": "A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Posttraumatic Stress Disorder",
        "Depression",
        "Alcohol-Related Disorders",
        "Suicidal Ideation",
        "Substance-Related Disorders",
        "Mild Cognitive Impairment",
        "Quality of Life",
        "Pain",
        "Wounds and Injury",
        "Brain Injuries",
        "Chronic Disease"
      ],
      "interventions": [
        {
          "name": "Motivational Interviewing",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cognitive Behavioral Therapy Elements",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Care Management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Fluoxetine",
          "type": "DRUG"
        },
        {
          "name": "Fluvoxamine",
          "type": "DRUG"
        },
        {
          "name": "Paroxetine",
          "type": "DRUG"
        },
        {
          "name": "Sertraline",
          "type": "DRUG"
        },
        {
          "name": "Citalopram",
          "type": "DRUG"
        },
        {
          "name": "Venlafaxine",
          "type": "DRUG"
        },
        {
          "name": "Duloxetine",
          "type": "DRUG"
        },
        {
          "name": "Mirtazapine",
          "type": "DRUG"
        },
        {
          "name": "Diphenhydramine",
          "type": "DRUG"
        },
        {
          "name": "Trazodone",
          "type": "DRUG"
        },
        {
          "name": "Prazosin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 635,
      "start_date": "2015-10",
      "completion_date": "2019-11",
      "has_results": true,
      "last_update_posted_date": "2021-07-02",
      "last_synced_at": "2026-06-11T07:07:12.227Z",
      "location_count": 24,
      "location_summary": "Scottsdale, Arizona • Beverly Hills, California • Sacramento, California + 20 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Beverly Hills",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "San Jose",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02655354"
    }
  ]
}