{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Misuse%2C+Opioid&page=2",
    "query": {
      "condition": "Misuse, Opioid",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Misuse%2C+Opioid&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T07:53:47.483Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05169281",
      "title": "Distribution of Medication Disposal Packets - Acute Opioid Prescribing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Orthopedic Surgery",
        "Neurosurgery",
        "Surgery",
        "Opioid Use",
        "Opioid Misuse"
      ],
      "interventions": [
        {
          "name": "Medication Disposal Packet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 657,
      "start_date": "2021-03-24",
      "completion_date": "2021-05-26",
      "has_results": false,
      "last_update_posted_date": "2023-06-02",
      "last_synced_at": "2026-07-24T07:53:47.483Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05169281"
    },
    {
      "nct_id": "NCT06288256",
      "title": "Neurocognitive and Genomic Predictors of Persistent Pain and Opioid Misuse After Spine Surgery",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lumbar Spine Pathology",
        "Elective Spine Surgery"
      ],
      "interventions": [
        {
          "name": "No Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2023-03-27",
      "completion_date": "2026-07",
      "has_results": false,
      "last_update_posted_date": "2024-10-16",
      "last_synced_at": "2026-07-24T07:53:47.483Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06288256"
    },
    {
      "nct_id": "NCT03495245",
      "title": "Identification of Potential Biomarkers for Pain",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Fibromyalgia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Rowan University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2018-03-28",
      "completion_date": "2021-09-30",
      "has_results": false,
      "last_update_posted_date": "2019-11-19",
      "last_synced_at": "2026-07-24T07:53:47.483Z",
      "location_count": 1,
      "location_summary": "Stratford, New Jersey",
      "locations": [
        {
          "city": "Stratford",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03495245"
    },
    {
      "nct_id": "NCT04839978",
      "title": "Community Trial in the Cherokee Nation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Abuse"
      ],
      "interventions": [
        {
          "name": "Connect Program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Communities Mobilizing for Change and Action (CMCA)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "15 Years to 17 Years"
      },
      "enrollment_count": 919,
      "start_date": "2021-09-29",
      "completion_date": "2024-12-31",
      "has_results": true,
      "last_update_posted_date": "2026-03-05",
      "last_synced_at": "2026-07-24T07:53:47.483Z",
      "location_count": 1,
      "location_summary": "Tahlequah, Oklahoma",
      "locations": [
        {
          "city": "Tahlequah",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04839978"
    },
    {
      "nct_id": "NCT04317053",
      "title": "Multi-Center Randomized Controlled Trial of Relay- NYC's Nonfatal Overdose Response Program",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Overdose"
      ],
      "interventions": [
        {
          "name": "RELAY",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 253,
      "start_date": "2020-10-08",
      "completion_date": "2023-07-01",
      "has_results": true,
      "last_update_posted_date": "2024-11-25",
      "last_synced_at": "2026-07-24T07:53:47.483Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04317053"
    },
    {
      "nct_id": "NCT04301895",
      "title": "Pupillary Unrest in Ambient Light, and Relationship to Opioid-Induced Respiratory Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Opioid; Intoxication, Perception Disturbance (Acute)",
        "Acute Pain",
        "Overdose of Opiate",
        "Respiratory Depression",
        "Safety Issues"
      ],
      "interventions": [
        {
          "name": "Continuous conversational interaction",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Remifentanil infusion",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "20 Years to 55 Years"
      },
      "enrollment_count": 20,
      "start_date": "2019-04-30",
      "completion_date": "2019-09-03",
      "has_results": false,
      "last_update_posted_date": "2020-03-10",
      "last_synced_at": "2026-07-24T07:53:47.483Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04301895"
    },
    {
      "nct_id": "NCT06429436",
      "title": "Vending Machine Naloxone Distribution for Your Community (VENDY)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Harm Reduction",
        "Naloxone",
        "Opioid Overdose"
      ],
      "interventions": [
        {
          "name": "VENDY",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 4000,
      "start_date": "2024-06-01",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-02",
      "last_synced_at": "2026-07-24T07:53:47.483Z",
      "location_count": 3,
      "location_summary": "Denver, Colorado • Frisco, Colorado • Pueblo, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Frisco",
          "state": "Colorado"
        },
        {
          "city": "Pueblo",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06429436"
    },
    {
      "nct_id": "NCT06303804",
      "title": "Prevention of Opioid Misuse and Overdose Deaths Among Hispanic/Latinx Adolescents: A Family-based Perspective",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Misuse"
      ],
      "interventions": [
        {
          "name": "Educational videos",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 6,
      "start_date": "2024-02-06",
      "completion_date": "2024-04-21",
      "has_results": false,
      "last_update_posted_date": "2026-04-07",
      "last_synced_at": "2026-07-24T07:53:47.483Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06303804"
    },
    {
      "nct_id": "NCT03895827",
      "title": "Recovery Initiation and Management After Overdose (RIMO) Experiment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid-use Disorder"
      ],
      "interventions": [
        {
          "name": "Recovery Initiation and Management after Overdose (RIMO)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Passive Referral to Treatment Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Chestnut Health Systems",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 251,
      "start_date": "2022-04-01",
      "completion_date": "2025-06-26",
      "has_results": false,
      "last_update_posted_date": "2026-03-18",
      "last_synced_at": "2026-07-24T07:53:47.483Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03895827"
    },
    {
      "nct_id": "NCT05343169",
      "title": "Community-based Education, Navigation, and Support Intervention for Military Veterans",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overdose",
        "Opioid Use Disorder",
        "HIV Infections"
      ],
      "interventions": [
        {
          "name": "Overdose Education and Naloxone Distribution",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Advanced Education in Safer Substance Use, Treatment, and Self-Care",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Social Service and Health Navigation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Peer Social Support",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "New York University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2022-10-21",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-03",
      "last_synced_at": "2026-07-24T07:53:47.483Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05343169"
    }
  ]
}