{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Mitochondrial+Genetic+Disorders&page=9", "query": { "condition": "Mitochondrial Genetic Disorders", "page": 9 }, "page_size": 10 }, "pagination": { "page": 9, "page_size": 10, "total_count": 210, "total_pages": 21, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Mitochondrial+Genetic+Disorders&page=10&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Mitochondrial+Genetic+Disorders&page=8&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-21T10:32:58.836Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00002156", "title": "A Randomized Comparison of Intravitreal ISIS 2922 Plus Ganciclovir Versus Ganciclovir as Treatment for Patients With Cytomegalovirus Retinitis ( CMVR )", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Cytomegalovirus Retinitis", "HIV Infections" ], "interventions": [ { "name": "Fomivirsen sodium", "type": "DRUG" }, { "name": "Ganciclovir", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Ionis Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 194, "start_date": null, "completion_date": null, "has_results": false, "last_update_posted_date": "2005-06-24", "last_synced_at": "2026-10-21T10:32:58.836Z", "location_count": 18, "location_summary": "Los Angeles, California • Pasadena, California • San Diego, California + 14 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Pasadena", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "San Jose", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00002156" }, { "nct_id": "NCT07531251", "title": "Clinical Trial in Patients With Barth Syndrome- 4TAZPower", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Barth Syndrome" ], "interventions": [ { "name": "Elamipretide", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Stealth BioTherapeutics Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "5 Years", "maximum_age": "55 Years", "sex": "MALE", "summary": "5 Years to 55 Years · Male only" }, "enrollment_count": 48, "start_date": "2026-07-02", "completion_date": "2029-11-30", "has_results": false, "last_update_posted_date": "2026-09-17", "last_synced_at": "2026-10-21T10:32:58.836Z", "location_count": 1, "location_summary": "Needham, Massachusetts", "locations": [ { "city": "Needham", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT07531251" }, { "nct_id": "NCT03913130", "title": "Extension Study to Study PQ-110-001 (NCT03140969)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Leber Congenital Amaurosis 10", "Blindness", "Leber Congenital Amaurosis", "Vision Disorders", "Sensation Disorders", "Neurologic Manifestations", "Eye Diseases", "Eye Diseases, Hereditary", "Eye Disorders Congenital", "Retinal Disease" ], "interventions": [ { "name": "QR-110", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Laboratoires Thea", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": null, "sex": "ALL", "summary": "6 Years and older" }, "enrollment_count": 9, "start_date": "2019-05-13", "completion_date": "2022-10-03", "has_results": true, "last_update_posted_date": "2024-10-15", "last_synced_at": "2026-10-21T10:32:58.836Z", "location_count": 2, "location_summary": "Iowa City, Iowa • Philadelphia, Pennsylvania", "locations": [ { "city": "Iowa City", "state": "Iowa" }, { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT03913130" }, { "nct_id": "NCT00002134", "title": "A Randomized, Controlled Study of the Safety and Preventive Efficacy of Oral Ganciclovir When Used in Conjunction With An Intravitreal Ganciclovir Implant in the Treatment of Cytomegalovirus Retinitis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cytomegalovirus Retinitis", "HIV Infections" ], "interventions": [ { "name": "Ganciclovir", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Roche Global Development", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": null, "sex": "ALL", "summary": "13 Years and older" }, "enrollment_count": 450, "start_date": null, "completion_date": null, "has_results": false, "last_update_posted_date": "2005-06-24", "last_synced_at": "2026-10-21T10:32:58.836Z", "location_count": 23, "location_summary": "Beverly Hills, California • Irvine, California • Los Angeles, California + 16 more", "locations": [ { "city": "Beverly Hills", "state": "California" }, { "city": "Irvine", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00002134" }, { "nct_id": "NCT01721733", "title": "Safety and Efficacy Study of EPI-743 in Children With Leigh Syndrome", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Leigh Syndrome" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "EPI-743 15 mg/kg", "type": "DRUG" }, { "name": "EPI-743 5 mg/kg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "PTC Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "6 Years to 17 Years" }, "enrollment_count": 35, "start_date": "2012-10-31", "completion_date": "2015-05-31", "has_results": false, "last_update_posted_date": "2020-08-31", "last_synced_at": "2026-10-21T10:32:58.836Z", "location_count": 4, "location_summary": "Palo Alto, California • Akron, Ohio • Houston, Texas + 1 more", "locations": [ { "city": "Palo Alto", "state": "California" }, { "city": "Akron", "state": "Ohio" }, { "city": "Houston", "state": "Texas" }, { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT01721733" }, { "nct_id": "NCT05028764", "title": "Determine Range of Tissue Frataxin Concentrations and Other Potential Biomarkers", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Friedreich Ataxia", "Healthy Volunteers" ], "interventions": [ { "name": "Buccal Swabs, Blood Draws and Skin Punch Biopsy", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Larimar Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 60, "start_date": "2021-08-04", "completion_date": "2022-02-04", "has_results": false, "last_update_posted_date": "2022-02-24", "last_synced_at": "2026-10-21T10:32:58.836Z", "location_count": 1, "location_summary": "Eatontown, New Jersey", "locations": [ { "city": "Eatontown", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT05028764" }, { "nct_id": "NCT05573698", "title": "Study to Evaluate Multiple Ascending Dose and Multi-Dose of DT-216 in Adult Patients With Friedreich Ataxia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Friedreich Ataxia" ], "interventions": [ { "name": "DT-216", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Design Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 32, "start_date": "2022-09-27", "completion_date": "2023-08-25", "has_results": false, "last_update_posted_date": "2024-02-29", "last_synced_at": "2026-10-21T10:32:58.836Z", "location_count": 1, "location_summary": "Eatontown, New Jersey", "locations": [ { "city": "Eatontown", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT05573698" }, { "nct_id": "NCT00056186", "title": "Transitional Life Events in Patients With Friedreich's Ataxia: Implications for Genetic Counseling", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Friedreich Ataxia" ], "interventions": [], "intervention_types": [], "sponsor": "National Human Genome Research Institute (NHGRI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 40, "start_date": "2003-03", "completion_date": "2004-01", "has_results": false, "last_update_posted_date": "2008-03-04", "last_synced_at": "2026-10-21T10:32:58.836Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00056186" }, { "nct_id": "NCT07478172", "title": "Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Neuromuscular Diseases (NMD)", "Amyotrophic Lateral Sclerosis", "Myasthenia Gravis", "Lambert-eaton Myasthenic Syndrome", "Primary Lateral Sclerosis", "Spinal Muscular Atrophy", "Charcot Marie Tooth Disease (CMT)", "Fascioscapulohumeral Muscular Dystrophy", "Inclusion Body Myositis", "Mitochondrial Myopathy", "Nemaline Myopathy", "Centronuclear Myopathy", "Postpolio Syndrome", "Pompe Disease (Late-onset)", "Chronic Inflammatory Demyelinating Polyneuropathy", "Hereditary Spastic Paraplegia", "Postural Orthostatic Tachycardia Syndrome (POTS)", "Progressive Muscular Atrophy" ], "interventions": [ { "name": "Whole-body Electrical Muscle Stimulation Exercise", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "University of Missouri-Columbia", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 50, "start_date": "2026-03-10", "completion_date": "2031-01-07", "has_results": false, "last_update_posted_date": "2026-03-17", "last_synced_at": "2026-10-21T10:32:58.836Z", "location_count": 1, "location_summary": "Columbia, Missouri", "locations": [ { "city": "Columbia", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT07478172" }, { "nct_id": "NCT07869654", "title": "A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ATI-105 in Healthy Adults", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Friedreich Ataxia", "Cardiomyopathies", "Central Nervous System Diseases", "Neuromuscular Diseases", "Mitochondrial Diseases", "Mitochondrial Dysfunction", "Genetic Disease" ], "interventions": [ { "name": "ATI-105", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Adjuvia Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 60, "start_date": "2026-10-26", "completion_date": "2027-06-27", "has_results": false, "last_update_posted_date": "2026-10-09", "last_synced_at": "2026-10-21T10:32:58.836Z", "location_count": 1, "location_summary": "Miami, Florida", "locations": [ { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT07869654" } ] }