{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Mitraclip", "query": { "condition": "Mitraclip" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 17, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Mitraclip&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-06-26T10:25:33.040Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT07131631", "title": "Secondary Mitral Regurgitation Treatment With MitraClip and Assessment by Cardiac Magnetic Resonance", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Heart Failure and Reduced Ejection Fraction", "Functional Mitral Regurgitation" ], "interventions": [ { "name": "Cardiac MRI", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Minneapolis Heart Institute Foundation", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 125, "start_date": "2022-03-03", "completion_date": "2027-07", "has_results": false, "last_update_posted_date": "2025-12-23", "last_synced_at": "2026-06-26T10:25:33.040Z", "location_count": 5, "location_summary": "Minneapolis, Minnesota • Charlotte, North Carolina • Cincinnati, Ohio + 2 more", "locations": [ { "city": "Minneapolis", "state": "Minnesota" }, { "city": "Charlotte", "state": "North Carolina" }, { "city": "Cincinnati", "state": "Ohio" }, { "city": "Cleveland", "state": "Ohio" }, { "city": "Falls Church", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT07131631" }, { "nct_id": "NCT01931956", "title": "Real World Expanded Multicenter Study of the MitraClip® System (REALISM)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Mitral Valve Insufficiency", "Mitral Valve Regurgitation", "Mitral Valve Incompetence", "Mitral Regurgitation", "Mitral Insufficiency" ], "interventions": [ { "name": "MitraClip® implant", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Abbott Medical Devices", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 965, "start_date": "2009-01-22", "completion_date": "2018-06", "has_results": true, "last_update_posted_date": "2018-12-04", "last_synced_at": "2026-06-26T10:25:33.040Z", "location_count": 38, "location_summary": "Los Angeles, California • Mountain View, California • Sacramento, California + 31 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Mountain View", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Washington D.C.", "state": "District of Columbia" } ], "official_url": "https://clinicaltrials.gov/study/NCT01931956" }, { "nct_id": "NCT07227675", "title": "Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional MR", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Mitral Regurgitation", "Mitral Valve Regurgitation" ], "interventions": [ { "name": "MitraClip® NT System", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Abbott Medical Devices", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 162, "start_date": "2017-10-23", "completion_date": "2024-03-31", "has_results": false, "last_update_posted_date": "2025-11-13", "last_synced_at": "2026-06-26T10:25:33.040Z", "location_count": 32, "location_summary": "La Jolla, California • Los Angeles, California • Mountain View, California + 25 more", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Mountain View", "state": "California" }, { "city": "Stanford", "state": "California" }, { "city": "Denver", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT07227675" }, { "nct_id": "NCT03706833", "title": "Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Degenerative Mitral Valve Disease", "Mitral Regurgitation", "Mitral Insufficiency", "Functional Mitral Regurgitation" ], "interventions": [ { "name": "Edwards PASCAL System", "type": "DEVICE" }, { "name": "Abbott Mitraclip System", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Edwards Lifesciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1247, "start_date": "2018-11-30", "completion_date": "2031-06-30", "has_results": false, "last_update_posted_date": "2026-04-09", "last_synced_at": "2026-06-26T10:25:33.040Z", "location_count": 68, "location_summary": "Phoenix, Arizona • Tucson, Arizona • La Jolla, California + 52 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03706833" }, { "nct_id": "NCT01940120", "title": "EVEREST II Pivotal Study High Risk Registry (HRR)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Mitral Valve Insufficiency", "Mitral Valve Regurgitation", "Mitral Valve Incompetence", "Mitral Regurgitation", "Mitral Insufficiency" ], "interventions": [ { "name": "Percutaneous mitral valve repair using MitraClip implant", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Abbott Medical Devices", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 78, "start_date": "2007-02", "completion_date": "2013-02", "has_results": true, "last_update_posted_date": "2018-11-07", "last_synced_at": "2026-06-26T10:25:33.040Z", "location_count": 2, "location_summary": "Evanston, Illinois • Indianapolis, Indiana", "locations": [ { "city": "Evanston", "state": "Illinois" }, { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT01940120" }, { "nct_id": "NCT07213531", "title": "Enhanced Valves Interventions and Safe AI Generated End Results", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Heart Valve Disease", "TAVI", "M-TEER", "TTVI", "TMVI", "T-TEER", "Mitraclip", "TriClip" ], "interventions": [ { "name": "Medical imaging analysis via artificial intelligence algorithms", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Montreal Heart Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 21000, "start_date": "2024-05-01", "completion_date": "2029-05", "has_results": false, "last_update_posted_date": "2025-10-09", "last_synced_at": "2026-06-26T10:25:33.040Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT07213531" }, { "nct_id": "NCT00209274", "title": "Pivotal Study of a Percutaneous Mitral Valve Repair System", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Mitral Valve Insufficiency", "Mitral Valve Regurgitation", "Mitral Valve Incompetence", "Mitral Regurgitation", "Mitral Insufficiency" ], "interventions": [ { "name": "Percutaneous mitral valve repair using MitraClip implant", "type": "DEVICE" }, { "name": "Mitral valve repair or replacement surgery", "type": "PROCEDURE" } ], "intervention_types": [ "DEVICE", "PROCEDURE" ], "sponsor": "Abbott Medical Devices", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 279, "start_date": "2005-08", "completion_date": "2014-12", "has_results": true, "last_update_posted_date": "2018-11-07", "last_synced_at": "2026-06-26T10:25:33.040Z", "location_count": 1, "location_summary": "Evanston, Illinois", "locations": [ { "city": "Evanston", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00209274" }, { "nct_id": "NCT03993938", "title": "Pleth Variability Index (PVI) as a Measure of Volume Status During Transcatheter Mitral Valve Repair", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Mitral Regurgitation" ], "interventions": [ { "name": "PVI measurement", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Henry Ford Health System", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 30, "start_date": "2019-10-01", "completion_date": "2021-06-01", "has_results": true, "last_update_posted_date": "2022-06-24", "last_synced_at": "2026-06-26T10:25:33.040Z", "location_count": 1, "location_summary": "Detroit, Michigan", "locations": [ { "city": "Detroit", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT03993938" }, { "nct_id": "NCT00209339", "title": "Feasibility Study of a Percutaneous Mitral Valve Repair System.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Mitral Valve Insufficiency", "Mitral Valve Regurgitation", "Mitral Valve Incompetence", "Mitral Regurgitation", "Mitral Insufficiency" ], "interventions": [ { "name": "Percutaneous mitral valve repair (MitraClip Implant)", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Abbott Medical Devices", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 55, "start_date": "2003-07", "completion_date": "2011-10", "has_results": true, "last_update_posted_date": "2018-11-07", "last_synced_at": "2026-06-26T10:25:33.040Z", "location_count": 1, "location_summary": "Evanston, Illinois", "locations": [ { "city": "Evanston", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00209339" }, { "nct_id": "NCT02924363", "title": "Effect of MitraClip on Acute and Chronic Reverse Cardiac Remodeling Assessed by CMR: The MITRA-REVERSE Study", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Mitral Regurgitation" ], "interventions": [ { "name": "Cardiac MRI with or without contrast dye", "type": "DIAGNOSTIC_TEST" }, { "name": "Blood sample", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Dipan Shah", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 54, "start_date": "2017-01", "completion_date": "2021-12", "has_results": false, "last_update_posted_date": "2026-04-20", "last_synced_at": "2026-06-26T10:25:33.040Z", "location_count": 2, "location_summary": "Atlanta, Georgia • Houston, Texas", "locations": [ { "city": "Atlanta", "state": "Georgia" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02924363" } ] }