{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Mixed+Connective+Tissue+Disease+%28MCTD%29",
    "query": {
      "condition": "Mixed Connective Tissue Disease (MCTD)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 11,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Mixed+Connective+Tissue+Disease+%28MCTD%29&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T01:45:31.439Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04402086",
      "title": "Rheumatology Patient Registry and Biorepository",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Rheumatic Diseases",
        "Adult Onset Still Disease",
        "Ankylosing Spondylitis",
        "Psoriatic Arthritis",
        "Reactive Arthritis",
        "Antiphospholipid Syndrome",
        "Systemic Lupus Erythematosus",
        "Behcet Disease",
        "Dermatomyositis",
        "Polymyositis",
        "Giant Cell Arteritis",
        "Lyme Disease",
        "Mixed Connective Tissue Disease",
        "Polymyalgia Rheumatica",
        "Rheumatoid Arthritis",
        "Sarcoidosis",
        "Systemic Sclerosis",
        "Scleroderma",
        "Sjogren's Syndrome",
        "Undifferentiated Connective Tissue Diseases"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 5000,
      "start_date": "2020-08-04",
      "completion_date": "2030-06-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-13",
      "last_synced_at": "2026-06-26T01:45:31.439Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04402086"
    },
    {
      "nct_id": "NCT06672822",
      "title": "Intralesional Injection of STS in Treatment of Calcinosis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Systemic Sclerosis (SSc)",
        "Dermatomyositis",
        "Mixed Connective Tissue Disease (MCTD)",
        "Calcinosis"
      ],
      "interventions": [
        {
          "name": "Sodium Thiosulfate (STS)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Robyn T. Domsic, MD, MPH",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2025-03-17",
      "completion_date": "2029-05-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-05",
      "last_synced_at": "2026-06-26T01:45:31.439Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06672822"
    },
    {
      "nct_id": "NCT00048776",
      "title": "Safety and Efficacy of Pletal (Cilostazol) for the Treatment of Juvenile Primary and Secondary Raynaud's Phenomenon",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Raynaud's Disease"
      ],
      "interventions": [
        {
          "name": "Pletal",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Otsuka America Pharmaceutical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "5 Years to 16 Years"
      },
      "enrollment_count": 75,
      "start_date": "2001-10",
      "completion_date": "2003-06",
      "has_results": false,
      "last_update_posted_date": "2005-07-19",
      "last_synced_at": "2026-06-26T01:45:31.439Z",
      "location_count": 19,
      "location_summary": "Anchorage, Alaska • Fresno, California • Madera, California + 16 more",
      "locations": [
        {
          "city": "Anchorage",
          "state": "Alaska"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Madera",
          "state": "California"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00048776"
    },
    {
      "nct_id": "NCT03269630",
      "title": "New Orleans Pulmonary Hypertension Biobank",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pulmonary Hypertension",
        "Systemic Sclerosis",
        "Mixed Connective Tissue Disease",
        "Heart Failure With Normal Ejection Fraction",
        "Healthy"
      ],
      "interventions": [
        {
          "name": "No intervention. Biospecimen collection only",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Louisiana State University Health Sciences Center in New Orleans",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 450,
      "start_date": "2017-12-29",
      "completion_date": "2027-10",
      "has_results": false,
      "last_update_posted_date": "2021-09-10",
      "last_synced_at": "2026-06-26T01:45:31.439Z",
      "location_count": 1,
      "location_summary": "New Orleans, Louisiana",
      "locations": [
        {
          "city": "New Orleans",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03269630"
    },
    {
      "nct_id": "NCT05715463",
      "title": "Rheumatology-based Adaptive Intervention for Social Determinants and Health Equity",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Rheumatoid Arthritis",
        "Palindromic Arthritis",
        "Juvenile Rheumatoid Arthritis",
        "Ankylosing Spondylitis",
        "Sacroiliitis",
        "Psoriatic Arthritis",
        "Mixed Connective Tissue Disease",
        "Lupus",
        "Enteropathic Arthropathies",
        "Systemic Sclerosis",
        "Sjogren's Syndrome",
        "Sicca Syndrome",
        "Inflammatory Arthritis",
        "Undifferentiated Connective Tissue Diseases"
      ],
      "interventions": [
        {
          "name": "Resource sheets",
          "type": "OTHER"
        },
        {
          "name": "Community Resource Specialist",
          "type": "OTHER"
        },
        {
          "name": "Nurse Navigator",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 101,
      "start_date": "2023-03-01",
      "completion_date": "2026-12-01",
      "has_results": false,
      "last_update_posted_date": "2025-10-15",
      "last_synced_at": "2026-06-26T01:45:31.439Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05715463"
    },
    {
      "nct_id": "NCT02741362",
      "title": "Safety and Efficacy of Adipose Derived Stem Cells in Refractory Rheumatoid Arthritis, Systemic Lupus Erythematosus or Sharp's Syndrome",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Systemic Lupus Erythematosus",
        "Rheumatoid Arthritis",
        "Sharp's Syndrome"
      ],
      "interventions": [
        {
          "name": "Intravenous injection of Stromal Vascular Fraction Cells (SVF) containing ADSCs",
          "type": "OTHER"
        },
        {
          "name": "Lipoaspiration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Arkansas Heart Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 2,
      "start_date": "2015-12",
      "completion_date": "2016-12-31",
      "has_results": false,
      "last_update_posted_date": "2017-03-03",
      "last_synced_at": "2026-06-26T01:45:31.439Z",
      "location_count": 1,
      "location_summary": "Little Rock, Arkansas",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02741362"
    },
    {
      "nct_id": "NCT01424033",
      "title": "A Clinical Trial for CTD-ILD Treatment",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Interstitial Lung Disease",
        "Connective Tissue Disease"
      ],
      "interventions": [
        {
          "name": "N-Acetylcysteine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2011-12",
      "completion_date": null,
      "has_results": true,
      "last_update_posted_date": "2017-04-06",
      "last_synced_at": "2026-06-26T01:45:31.439Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01424033"
    },
    {
      "nct_id": "NCT00522002",
      "title": "CLUE Study: Connective Tissue Disease Leg Ulcer Etiology Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Connective Tissue Diseases",
        "Blood Coagulation Disorders",
        "Leg Ulcers",
        "Rheumatoid Arthritis",
        "Systemic Lupus Erythematosus",
        "Systemic Scleroderma",
        "Mixed Connective Tissue Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "George Washington University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2007-08",
      "completion_date": "2010-06",
      "has_results": false,
      "last_update_posted_date": "2017-08-30",
      "last_synced_at": "2026-06-26T01:45:31.439Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00522002"
    },
    {
      "nct_id": "NCT00582881",
      "title": "Characteristics and Disease Progression of Mixed Connective Tissue Disease and Systemic Lupus Erythematosus",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mixed Connective Tissue Disease (MCTD)",
        "Systemic Lupus Erythematosus (SLE)"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 124,
      "start_date": "2007-10",
      "completion_date": "2025-06-27",
      "has_results": false,
      "last_update_posted_date": "2026-03-19",
      "last_synced_at": "2026-06-26T01:45:31.439Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00582881"
    },
    {
      "nct_id": "NCT07180537",
      "title": "Creating Health Course Study for People With Rheumatological Conditions",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Rheumatoid Arthritis",
        "Sjogren's Syndrome",
        "Systemic Lupus Erythematosus",
        "Mixed Connective Tissue Disease",
        "Psoriatic Arthritis"
      ],
      "interventions": [
        {
          "name": "Creating Health Online Course",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Delayed access to Creating Health Online Course",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Terry L. Wahls",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 200,
      "start_date": "2025-12-01",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-01-08",
      "last_synced_at": "2026-06-26T01:45:31.439Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07180537"
    }
  ]
}