{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Mixed+Mania+Bipolar+Disorder&page=2", "query": { "condition": "Mixed Mania Bipolar Disorder", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Mixed+Mania+Bipolar+Disorder&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-05-22T09:47:55.400Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00110461", "title": "Aripiprazole in Children and Adolescents With Bipolar I Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bipolar Disorder" ], "interventions": [ { "name": "Aripiprazole", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Otsuka Pharmaceutical Development & Commercialization, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "10 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "10 Years to 17 Years" }, "enrollment_count": 296, "start_date": "2005-03", "completion_date": "2007-02", "has_results": true, "last_update_posted_date": "2012-05-21", "last_synced_at": "2026-05-22T09:47:55.400Z", "location_count": 53, "location_summary": "Scottsdale, Arizona • Little Rock, Arkansas • National City, California + 50 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "National City", "state": "California" }, { "city": "Orange", "state": "California" }, { "city": "Pasadena", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00110461" }, { "nct_id": "NCT00277212", "title": "A Phase IV Study of the Safety and Efficacy of Aripiprazole in Combination With Lamotrigine in the Long-Term Maintenance Treatment of Patients With Bipolar I Disorder With A Recent Manic or Mixed Episode", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Bipolar Disorder" ], "interventions": [ { "name": "Lamotrigine + Aripiprazole", "type": "DRUG" }, { "name": "Lamotrigine + Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Otsuka Pharmaceutical Development & Commercialization, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1169, "start_date": "2005-12-01", "completion_date": "2009-07-01", "has_results": true, "last_update_posted_date": "2026-05-13", "last_synced_at": "2026-05-22T09:47:55.400Z", "location_count": 62, "location_summary": "Birmingham, Alabama • Tucson, Arizona • Anaheim, California + 55 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Anaheim", "state": "California" }, { "city": "Costa Mesa", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00277212" }, { "nct_id": "NCT07288320", "title": "An Assessment of Efficacy, Safety, and Pharmacokinetics of NBI-1117568 in Adults With Bipolar I Disorder With Current Mania", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Bipolar I Disorder", "Mania" ], "interventions": [ { "name": "NBI-1117568", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Neurocrine Biosciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 150, "start_date": "2025-12-24", "completion_date": "2028-02", "has_results": false, "last_update_posted_date": "2026-03-24", "last_synced_at": "2026-05-22T09:47:55.400Z", "location_count": 6, "location_summary": "Garden Grove, California • Hollywood, California • San Diego, California + 3 more", "locations": [ { "city": "Garden Grove", "state": "California" }, { "city": "Hollywood", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Gaithersburg", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT07288320" }, { "nct_id": "NCT00309699", "title": "A Study to Evaluate the Efficacy and Safety of Flexible Doses of Extended-release (ER) Paliperidone Compared With Flexible Doses of Quetiapine and Placebo in Patients With Bipolar I Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bipolar Disorder", "Mood Disorders" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Quetiapine", "type": "DRUG" }, { "name": "Paliperidone ER", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Johnson & Johnson Pharmaceutical Research & Development, L.L.C.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 493, "start_date": "2006-04", "completion_date": "2007-11", "has_results": false, "last_update_posted_date": "2014-06-20", "last_synced_at": "2026-05-22T09:47:55.400Z", "location_count": 22, "location_summary": "Cerritos, California • Garden Grove, California • Oceanside, California + 19 more", "locations": [ { "city": "Cerritos", "state": "California" }, { "city": "Garden Grove", "state": "California" }, { "city": "Oceanside", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Bradenton", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00309699" }, { "nct_id": "NCT00067262", "title": "An Outpatient Study of the Effectiveness and Safety of Depakote ER in the Treatment of Mania/Bipolar Disorder in Children and Adolescents", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bipolar Disorder" ], "interventions": [ { "name": "Divalproex Sodium Extended-Release Tablets", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Abbott", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "10 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "10 Years to 17 Years" }, "enrollment_count": 150, "start_date": "2003-03", "completion_date": null, "has_results": false, "last_update_posted_date": "2006-08-04", "last_synced_at": "2026-05-22T09:47:55.400Z", "location_count": 16, "location_summary": "Stanford, California • Washington D.C., District of Columbia • Altamonte Springs, Florida + 13 more", "locations": [ { "city": "Stanford", "state": "California" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Altamonte Springs", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "North Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00067262" }, { "nct_id": "NCT00982020", "title": "Study in Adolescents With Schizophrenia or Bipolar Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Bipolar I Disorder", "Schizophrenia" ], "interventions": [ { "name": "Olanzapine", "type": "DRUG" }, { "name": "Standard behavioral weight intervention", "type": "BEHAVIORAL" }, { "name": "Intense behavioral weight intervention", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "Eli Lilly and Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "13 Years to 17 Years" }, "enrollment_count": 203, "start_date": "2009-09", "completion_date": "2013-05", "has_results": true, "last_update_posted_date": "2014-12-17", "last_synced_at": "2026-05-22T09:47:55.400Z", "location_count": 4, "location_summary": "Lauderhill, Florida • Bloomfield Hills, Michigan • St Louis, Missouri + 1 more", "locations": [ { "city": "Lauderhill", "state": "Florida" }, { "city": "Bloomfield Hills", "state": "Michigan" }, { "city": "St Louis", "state": "Missouri" }, { "city": "Bellevue", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT00982020" }, { "nct_id": "NCT03573297", "title": "A Cariprazine Study in the Prevention of Relapse in Bipolar I Disorder Patients Whose Current Episode is Manic or Depressive, With or Without Mixed Features", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bipolar I Disorder", "Mania", "Depression" ], "interventions": [ { "name": "Cariprazine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AbbVie", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 901, "start_date": "2018-06-15", "completion_date": "2022-09-05", "has_results": true, "last_update_posted_date": "2023-09-28", "last_synced_at": "2026-05-22T09:47:55.400Z", "location_count": 46, "location_summary": "Little Rock, Arkansas • Rogers, Arkansas • Anaheim, California + 39 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "Rogers", "state": "Arkansas" }, { "city": "Anaheim", "state": "California" }, { "city": "Anaheim", "state": "California" }, { "city": "Bellflower", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03573297" }, { "nct_id": "NCT00223509", "title": "Lamictal As Add on Treatment in Mixed States of Bipolar Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Bipolar Disorder" ], "interventions": [ { "name": "Lamotrigine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The University of Texas Health Science Center at San Antonio", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "13 Years to 75 Years" }, "enrollment_count": 28, "start_date": "2005-08", "completion_date": "2007-11", "has_results": false, "last_update_posted_date": "2012-06-20", "last_synced_at": "2026-05-22T09:47:55.400Z", "location_count": 2, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00223509" }, { "nct_id": "NCT06951698", "title": "A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bipolar-I Disorder With Mania or Mania With Mixed Features" ], "interventions": [ { "name": "KarXT", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Bristol-Myers Squibb", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 274, "start_date": "2025-06-11", "completion_date": "2026-11-01", "has_results": false, "last_update_posted_date": "2026-04-14", "last_synced_at": "2026-05-22T09:47:55.400Z", "location_count": 22, "location_summary": "Bentonville, Arkansas • Little Rock, Arkansas • Anaheim, California + 18 more", "locations": [ { "city": "Bentonville", "state": "Arkansas" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Anaheim", "state": "California" }, { "city": "Bellflower", "state": "California" }, { "city": "Cerritos", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06951698" }, { "nct_id": "NCT01195363", "title": "Quetiapine Sr as Adjunctive Treatment In Mixed States of Bipolar Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Bipolar Disorder" ], "interventions": [ { "name": "quetiapine SR", "type": "DRUG" }, { "name": "quetiapine sr placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The University of Texas Health Science Center at San Antonio", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 28, "start_date": "2007-04", "completion_date": "2011-06", "has_results": true, "last_update_posted_date": "2017-03-23", "last_synced_at": "2026-05-22T09:47:55.400Z", "location_count": 1, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01195363" } ] }