{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Moderate+to+Severe+Chronic+Pain&page=2", "query": { "condition": "Moderate to Severe Chronic Pain", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Moderate+to+Severe+Chronic+Pain&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-06-11T04:17:40.488Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01256450", "title": "Efficacy and Safety Study of Buprenorphine HCl Buccal Film in Subjects With Low Back Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pain", "Low Back Pain" ], "interventions": [ { "name": "Buprenorphine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "BioDelivery Sciences International", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 334, "start_date": "2010-11", "completion_date": "2011-07", "has_results": true, "last_update_posted_date": "2017-02-27", "last_synced_at": "2026-06-11T04:17:40.488Z", "location_count": 24, "location_summary": "Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 21 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Fresno", "state": "California" }, { "city": "La Jolla", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01256450" }, { "nct_id": "NCT00667654", "title": "Safety and Tolerability of 4975 in the Treatment of Moderate to Severe Knee Pain Due to Osteoarthritis (OA)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Osteoarthritis of the Knee" ], "interventions": [ { "name": "CNTX-4975", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Centrexion Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 54, "start_date": "2007-08", "completion_date": "2016-08", "has_results": false, "last_update_posted_date": "2016-12-06", "last_synced_at": "2026-06-11T04:17:40.488Z", "location_count": 1, "location_summary": "Worcester, Massachusetts", "locations": [ { "city": "Worcester", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00667654" }, { "nct_id": "NCT00485225", "title": "Open Label, Safety Study of EN3270 in Patients With Moderate to Severe Non-malignant, Chronic Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic, Non Malignant Pain" ], "interventions": [ { "name": "EN3270", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Durect", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 77, "start_date": "2007-06", "completion_date": "2008-07", "has_results": false, "last_update_posted_date": "2012-02-23", "last_synced_at": "2026-06-11T04:17:40.488Z", "location_count": 1, "location_summary": "Berlin, New Jersey", "locations": [ { "city": "Berlin", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT00485225" }, { "nct_id": "NCT03285646", "title": "Evaluate the Efficacy and Safety of Fasinumab in Patients With Moderate-to-Severe Chronic Low Back Pain and Osteoarthritis of the Hip or Knee", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Low Back Pain", "Osteoarthritis" ], "interventions": [ { "name": "Fasinumab", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Regeneron Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 63, "start_date": "2017-10-30", "completion_date": "2019-05-02", "has_results": true, "last_update_posted_date": "2021-06-30", "last_synced_at": "2026-06-11T04:17:40.488Z", "location_count": 56, "location_summary": "Phoenix, Arizona • Tucson, Arizona • Anaheim, California + 47 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Anaheim", "state": "California" }, { "city": "Anaheim", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03285646" }, { "nct_id": "NCT01060254", "title": "A Study to Evaluate the Pain Relieving Effects, Safety, and Tolerability of JNJ-42160443 for the Relief of Bladder Pain", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Cystitis, Interstitial", "Urologic Diseases", "Urinary Bladder Diseases", "Cystitis" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "JNJ-42160443", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Johnson & Johnson Pharmaceutical Research & Development, L.L.C.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 31, "start_date": "2010-04-06", "completion_date": "2011-06-24", "has_results": false, "last_update_posted_date": "2021-10-18", "last_synced_at": "2026-06-11T04:17:40.488Z", "location_count": 20, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Glendora, California + 17 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Glendora", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Aventura", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01060254" }, { "nct_id": "NCT01688947", "title": "Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Postherpetic Neuralgia (PHN)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Postherpetic Neuralgia", "Pain" ], "interventions": [ { "name": "V116517 50-mg tablets", "type": "DRUG" }, { "name": "V116517 30-mg tablets", "type": "DRUG" }, { "name": "Pregabalin capsules", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Purdue Pharma LP", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "21 Years to 90 Years" }, "enrollment_count": 105, "start_date": "2012-09", "completion_date": "2014-04", "has_results": false, "last_update_posted_date": "2014-05-12", "last_synced_at": "2026-06-11T04:17:40.488Z", "location_count": 28, "location_summary": "Tucson, Arizona • La Jolla, California • North Hollywood, California + 25 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "La Jolla", "state": "California" }, { "city": "North Hollywood", "state": "California" }, { "city": "Boca Raton", "state": "Florida" }, { "city": "Bradenton", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01688947" }, { "nct_id": "NCT00538850", "title": "Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Cancer" ], "interventions": [ { "name": "Fentanyl sublingual spray", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "INSYS Therapeutics Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 130, "start_date": "2007-10", "completion_date": "2010-10", "has_results": true, "last_update_posted_date": "2014-03-05", "last_synced_at": "2026-06-11T04:17:40.488Z", "location_count": 1, "location_summary": "Chandler, Arizona", "locations": [ { "city": "Chandler", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT00538850" }, { "nct_id": "NCT00487435", "title": "An Open-label Extension Study With Flexible Dosing of Extended-release (ER) Tapentadol (CG5503) to Treat Patients With Moderate to Severe Chronic Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pain", "Osteoarthritis", "Low Back Pain" ], "interventions": [ { "name": "Tapentadol (CG5503) Extended Release (ER)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Johnson & Johnson Pharmaceutical Research & Development, L.L.C.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1166, "start_date": "2007-06", "completion_date": "2009-06", "has_results": true, "last_update_posted_date": "2014-05-09", "last_synced_at": "2026-06-11T04:17:40.488Z", "location_count": 118, "location_summary": "Birmingham, Alabama • Hoover, Alabama • Mobile, Alabama + 115 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Hoover", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Mesa", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT00487435" }, { "nct_id": "NCT01431742", "title": "Longterm Safety Study of BEMA Buprenorphine in Subjects With Chronic Low Back Pain", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pain", "Low Back Pain" ], "interventions": [ { "name": "BEMA Buprenorphine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "BioDelivery Sciences International", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2012-07", "completion_date": "2013-07", "has_results": false, "last_update_posted_date": "2012-04-17", "last_synced_at": "2026-06-11T04:17:40.488Z", "location_count": 1, "location_summary": "Marietta, Georgia", "locations": [ { "city": "Marietta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT01431742" }, { "nct_id": "NCT00347685", "title": "A One-year, Open-label Study to Assess the Safety and Effectiveness of Extended Release Tramadol HCl in the Treatment of Chronic, Non-malignant Pain.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Pain" ], "interventions": [ { "name": "tramadol ER", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bausch Health Americas, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 650, "start_date": "2000-10", "completion_date": "2003-02", "has_results": false, "last_update_posted_date": "2012-06-21", "last_synced_at": "2026-06-11T04:17:40.488Z", "location_count": 1, "location_summary": "Gainesville, Florida", "locations": [ { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00347685" } ] }