{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Moderate-to-severe+Chronic+Low+Back+Pain", "query": { "condition": "Moderate-to-severe Chronic Low Back Pain" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 31, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Moderate-to-severe+Chronic+Low+Back+Pain&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-25T20:00:05.648Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01043263", "title": "Efficacy and Safety of EN3324 (Axomadol) in Subjects With Chronic Low Back Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Low Back Pain" ], "interventions": [ { "name": "EN3324 (axomadol)", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Grünenthal GmbH", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 236, "start_date": "2009-12", "completion_date": "2011-06", "has_results": false, "last_update_posted_date": "2015-04-02", "last_synced_at": "2026-09-25T20:00:05.648Z", "location_count": 59, "location_summary": "Phoenix, Arizona • Tucson, Arizona • Tuscon, Arizona + 43 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Tuscon", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT01043263" }, { "nct_id": "NCT01452529", "title": "Efficacy and Safety of Hydrocodone Bitartrate (HYD) in Subjects With Moderate to Severe Chronic Low Back Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Low Back Pain" ], "interventions": [ { "name": "Hydrocodone bitartrate q24h film-coated tablets", "type": "DRUG" }, { "name": "Placebo to match hydrocodone bitartrate q24h tablets", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Purdue Pharma LP", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 905, "start_date": "2011-10", "completion_date": "2013-10", "has_results": true, "last_update_posted_date": "2020-03-10", "last_synced_at": "2026-09-25T20:00:05.648Z", "location_count": 102, "location_summary": "Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 83 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT01452529" }, { "nct_id": "NCT01298765", "title": "Longterm Safety Study of BEMA Buprenorphine in Subjects With Chronic Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pain", "Low Back Pain", "Osteoarthritis", "Neuropathic Pain" ], "interventions": [ { "name": "BEMA Buprenorphine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "BioDelivery Sciences International", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 302, "start_date": "2011-03", "completion_date": "2012-08", "has_results": true, "last_update_posted_date": "2018-08-07", "last_synced_at": "2026-09-25T20:00:05.648Z", "location_count": 26, "location_summary": "Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 23 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Arcadia", "state": "California" }, { "city": "Fresno", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01298765" }, { "nct_id": "NCT01685684", "title": "Oxycodone DETERx™ Versus Placebo in Chronic Low Back Pain (CLBP)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Low Back Pain" ], "interventions": [ { "name": "Oxycodone DETERx", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Collegium Pharmaceutical, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 740, "start_date": "2012-08", "completion_date": "2014-07", "has_results": true, "last_update_posted_date": "2020-10-19", "last_synced_at": "2026-09-25T20:00:05.648Z", "location_count": 45, "location_summary": "Mesa, Arizona • Phoenix, Arizona • Tucson, Arizona + 41 more", "locations": [ { "city": "Mesa", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Anaheim", "state": "California" }, { "city": "Anaheim", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01685684" }, { "nct_id": "NCT02716857", "title": "Efficacy and Safety of Egalet-002 in Patients With Moderate-to-Severe Chronic Low Back Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Moderate-to-severe Chronic Low Back Pain" ], "interventions": [ { "name": "Oxycodone extended-release", "type": "DRUG" }, { "name": "Placebo of oxycodone extended-release", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Egalet Ltd", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 549, "start_date": "2016-03", "completion_date": "2017-11", "has_results": false, "last_update_posted_date": "2018-03-05", "last_synced_at": "2026-09-25T20:00:05.648Z", "location_count": 74, "location_summary": "Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 65 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT02716857" }, { "nct_id": "NCT03285646", "title": "Evaluate the Efficacy and Safety of Fasinumab in Patients With Moderate-to-Severe Chronic Low Back Pain and Osteoarthritis of the Hip or Knee", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Low Back Pain", "Osteoarthritis" ], "interventions": [ { "name": "Fasinumab", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Regeneron Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 63, "start_date": "2017-10-30", "completion_date": "2019-05-02", "has_results": true, "last_update_posted_date": "2021-06-30", "last_synced_at": "2026-09-25T20:00:05.648Z", "location_count": 56, "location_summary": "Phoenix, Arizona • Tucson, Arizona • Anaheim, California + 47 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Anaheim", "state": "California" }, { "city": "Anaheim", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03285646" }, { "nct_id": "NCT02620020", "title": "A Study to Determine the Efficacy and Safety of Fasinumab for the Treatment of Adults With Chronic Low Back Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Low Back Pain" ], "interventions": [ { "name": "Fasinumab", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Regeneron Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "35 Years", "maximum_age": null, "sex": "ALL", "summary": "35 Years and older" }, "enrollment_count": 563, "start_date": "2016-01-26", "completion_date": "2017-09-13", "has_results": true, "last_update_posted_date": "2020-06-16", "last_synced_at": "2026-09-25T20:00:05.648Z", "location_count": 58, "location_summary": "Birmingham, Alabama • Chandler, Arizona • Glendale, Arizona + 55 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Chandler", "state": "Arizona" }, { "city": "Glendale", "state": "Arizona" }, { "city": "Mesa", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT02620020" }, { "nct_id": "NCT01358526", "title": "Efficacy and Safety of Oxycodone/Naloxone Controlled-release Tablets (OXN) Compared to Placebo in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Low Back Pain" ], "interventions": [ { "name": "Oxycodone/Naloxone Controlled-release", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Purdue Pharma LP", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1095, "start_date": "2011-05", "completion_date": "2012-11", "has_results": true, "last_update_posted_date": "2015-11-11", "last_synced_at": "2026-09-25T20:00:05.648Z", "location_count": 151, "location_summary": "Birmingham, Alabama • Haleyville, Alabama • Huntsville, Alabama + 123 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Haleyville", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT01358526" }, { "nct_id": "NCT01755546", "title": "Long-term Open-Label Safety Study to Evaluate EN3409", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Low Back Pain", "Osteoarthritis", "Neuropathic Pain" ], "interventions": [ { "name": "EN3409", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "BioDelivery Sciences International", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 304, "start_date": "2012-12", "completion_date": "2014-11", "has_results": true, "last_update_posted_date": "2018-10-18", "last_synced_at": "2026-09-25T20:00:05.648Z", "location_count": 57, "location_summary": "Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 52 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Anaheim", "state": "California" }, { "city": "Escondido", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01755546" }, { "nct_id": "NCT01427270", "title": "Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) for Uncontrolled Moderate - Severe Low Back Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Low Back Pain" ], "interventions": [ { "name": "Oxycodone/Naloxone controlled-release", "type": "DRUG" }, { "name": "Oxycodone HCl controlled-release", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Purdue Pharma LP", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 455, "start_date": "2011-08", "completion_date": "2014-10", "has_results": false, "last_update_posted_date": "2014-11-07", "last_synced_at": "2026-09-25T20:00:05.648Z", "location_count": 170, "location_summary": "Alabaster, Alabama • Birmingham, Alabama • Gulf Shores, Alabama + 137 more", "locations": [ { "city": "Alabaster", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Gulf Shores", "state": "Alabama" }, { "city": "Homewood", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT01427270" } ] }