{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Monochorionic+Twins",
    "query": {
      "condition": "Monochorionic Twins"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 12,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Monochorionic+Twins&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T08:57:06.596Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02621645",
      "title": "TRAP Intervention STudy: Early Versus Late Intervention for Twin Reversed Arterial Perfusion Sequence",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Twin Reversal Arterial Perfusion Syndrome"
      ],
      "interventions": [
        {
          "name": "Early selective reduction of TRAP mass",
          "type": "PROCEDURE"
        },
        {
          "name": "Late selective reduction of TRAP mass",
          "type": "PROCEDURE"
        },
        {
          "name": "Ultrasound-guided intrafetal ablation using a 18 to 20 Gauge needle",
          "type": "DEVICE"
        },
        {
          "name": "Ultrasound-guided intrafetal ablation using a 17 to 20 Gauge needle",
          "type": "DEVICE"
        },
        {
          "name": "Laser coagulation of the cord or anastomising vessels through a 17 Gauge to 7 French trocar, with a 1-1,3 mm fetoscope and a 400 µm laser fiber",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Universitaire Ziekenhuizen KU Leuven",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 126,
      "start_date": "2016-05",
      "completion_date": "2025-06",
      "has_results": false,
      "last_update_posted_date": "2024-07-10",
      "last_synced_at": "2026-07-22T08:57:06.596Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02621645"
    },
    {
      "nct_id": "NCT05008744",
      "title": "Laser Photocoagulation of Communicating Vessels in Twin-to-Twin Transfusion Syndrome",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Twin to Twin Transfusion as Antepartum Condition",
        "Monochorionic Diamniotic Placenta"
      ],
      "interventions": [
        {
          "name": "Fetoscopic laser ablation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Seattle Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 2000,
      "start_date": "2021-10-01",
      "completion_date": "2031-10-01",
      "has_results": false,
      "last_update_posted_date": "2024-04-19",
      "last_synced_at": "2026-07-22T08:57:06.596Z",
      "location_count": 2,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05008744"
    },
    {
      "nct_id": "NCT05952583",
      "title": "Selective Fetal Growth Restriction in Monochorionic Twins - an International Investigation",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Twin; Pregnancy, Affecting Fetus or Newborn",
        "Fetal Growth Retardation",
        "Twin Monochorionic Diamniotic Placenta",
        "Twin Diseases"
      ],
      "interventions": [
        {
          "name": "Ultrasound",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Leiden University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 274,
      "start_date": "2023-02-17",
      "completion_date": "2028-03-01",
      "has_results": false,
      "last_update_posted_date": "2024-04-15",
      "last_synced_at": "2026-07-22T08:57:06.596Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05952583"
    },
    {
      "nct_id": "NCT04432168",
      "title": "The TAPS Trial - Fetoscopic Laser Surgery for Twin Anemia Polycythemia Sequence",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Twin Anemia Polycythemia Sequence"
      ],
      "interventions": [
        {
          "name": "Fetoscopic Laser Surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard Treatment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Leiden University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 44,
      "start_date": "2019-04-30",
      "completion_date": "2024-04-30",
      "has_results": false,
      "last_update_posted_date": "2020-06-16",
      "last_synced_at": "2026-07-22T08:57:06.596Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04432168"
    },
    {
      "nct_id": "NCT06056635",
      "title": "A Prospective Study on the Role of Karl Storz Curved and Straight Fetoscopes (11508AAK and 11506AAK) for Fetoscopic Intrauterine Procedures",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fetal Conditions",
        "Maternal; Procedure",
        "Pregnancy Related",
        "Twin to Twin Transfusion Syndrome",
        "In Utero Procedure Affecting Fetus or Newborn",
        "Chorion; Abnormal",
        "Twin Reversal Arterial Perfusion Syndrome",
        "Twin Monochorionic Monoamniotic Placenta",
        "Chorioangioma",
        "Vasa Previa"
      ],
      "interventions": [
        {
          "name": "Karl Storz Curved Scope",
          "type": "DEVICE"
        },
        {
          "name": "Karl Storz Straight Scope",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 50,
      "start_date": "2024-08-15",
      "completion_date": "2027-05-01",
      "has_results": false,
      "last_update_posted_date": "2024-09-25",
      "last_synced_at": "2026-07-22T08:57:06.596Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06056635"
    },
    {
      "nct_id": "NCT00341263",
      "title": "Maternal and Umbilical Cord Hormone Concentrations in Twin and Singleton Pregnancies",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Normal Pregnancy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 60 Years · Female only"
      },
      "enrollment_count": 111,
      "start_date": "2003-11-21",
      "completion_date": "2020-02-19",
      "has_results": false,
      "last_update_posted_date": "2020-02-21",
      "last_synced_at": "2026-07-22T08:57:06.596Z",
      "location_count": 1,
      "location_summary": "Hanover, New Hampshire",
      "locations": [
        {
          "city": "Hanover",
          "state": "New Hampshire"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00341263"
    },
    {
      "nct_id": "NCT03775954",
      "title": "Fetal Electrophysiologic Abnormalities in High-Risk Pregnancies Associated With Fetal Demise",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "High Risk Pregnancy",
        "Congenital Heart Disease",
        "Fetal Hydrops",
        "Twin Monochorionic Monoamniotic Placenta",
        "Gastroschisis",
        "Fetal Demise",
        "Stillbirth",
        "Fetal Arrhythmia",
        "Long QT Syndrome",
        "Intrauterine Fetal Death",
        "Sudden Infant Death",
        "Pregnancy Loss",
        "Twin Twin Transfusion Syndrome",
        "Birth Defect",
        "Fetal Cardiac Anomaly",
        "Fetal Cardiac Disorder",
        "Fetal Death",
        "Brugada Syndrome",
        "Fetal Tachycardia"
      ],
      "interventions": [
        {
          "name": "Fetal Magnetocardiogram and Neonatal Electrocardiogram",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Substudy only: Maternal/Infant Pharmacogenomic assessment postnatally",
          "type": "GENETIC"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "GENETIC"
      ],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2018-07-01",
      "completion_date": "2028-11-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-04",
      "last_synced_at": "2026-07-22T08:57:06.596Z",
      "location_count": 2,
      "location_summary": "Madison, Wisconsin • Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        },
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03775954"
    },
    {
      "nct_id": "NCT03449823",
      "title": "Renal Artery Dopplers in Twin Twin Transfusion Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Twin Twin Transfusion Syndrome"
      ],
      "interventions": [
        {
          "name": "Doppler ultrasound of fetal renal artery",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 24,
      "start_date": "2016-09-09",
      "completion_date": "2018-06-30",
      "has_results": false,
      "last_update_posted_date": "2018-07-18",
      "last_synced_at": "2026-07-22T08:57:06.596Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03449823"
    },
    {
      "nct_id": "NCT06022510",
      "title": "Safety and Efficacy of Fetoscopes Used in Fetoscopic Selective Laser Photocoagulation",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Twin Monochorionic Diamniotic Placenta"
      ],
      "interventions": [
        {
          "name": "Fetoscopy Sets for Anterior and Posterior Placentas",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Michael A Belfort",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2025-04",
      "completion_date": "2025-04-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-29",
      "last_synced_at": "2026-07-22T08:57:06.596Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06022510"
    },
    {
      "nct_id": "NCT05543499",
      "title": "Database of Monochorionic Pregnancies",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Monochorionic Diamniotic Placenta",
        "Monochorial Monoamniotic Placenta",
        "Twin; Complicating Pregnancy",
        "Twin to Twin Transfusion Syndrome",
        "Twin Reversal Arterial Perfusion Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1200,
      "start_date": "2022-10-01",
      "completion_date": "2027-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-28",
      "last_synced_at": "2026-07-22T08:57:06.596Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05543499"
    }
  ]
}