{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Mucopolysaccharidosis+%28MPS%29",
    "query": {
      "condition": "Mucopolysaccharidosis (MPS)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 117,
    "total_pages": 12,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Mucopolysaccharidosis+%28MPS%29&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T10:41:58.948Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03811028",
      "title": "A Study to Assess the Safety, Tolerability, and Efficacy of Long-term SOBI003 Treatment in Pediatric MPS IIIA Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Sanfilippo Syndrome Type A (MPS IIIA)"
      ],
      "interventions": [
        {
          "name": "SOBI003",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Swedish Orphan Biovitrum",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Months",
        "maximum_age": "78 Months",
        "sex": "ALL",
        "summary": "18 Months to 78 Months"
      },
      "enrollment_count": 6,
      "start_date": "2019-01-19",
      "completion_date": "2021-05-07",
      "has_results": true,
      "last_update_posted_date": "2022-02-25",
      "last_synced_at": "2026-06-10T10:41:58.948Z",
      "location_count": 2,
      "location_summary": "Oakland, California • Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03811028"
    },
    {
      "nct_id": "NCT04088734",
      "title": "Gene Transfer Study of ABO-102 in Patients With Middle and Advanced Phases of MPS IIIA Disease",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "MPS IIIA",
        "Sanfilippo Syndrome",
        "Sanfilippo A",
        "Mucopolysaccharidosis III"
      ],
      "interventions": [
        {
          "name": "ABO-102",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ultragenyx Pharmaceutical Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "2 Years to 18 Years"
      },
      "enrollment_count": 5,
      "start_date": "2019-09-18",
      "completion_date": "2022-03-10",
      "has_results": true,
      "last_update_posted_date": "2023-07-25",
      "last_synced_at": "2026-06-10T10:41:58.948Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04088734"
    },
    {
      "nct_id": "NCT02371226",
      "title": "Safety and Dose Ranging Study of Insulin Receptor MAb-IDUA Fusion Protein in Patients With MPS I",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Mucopolysaccharidosis I"
      ],
      "interventions": [
        {
          "name": "AGT-181 (HIRMAb-IDUA)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "ArmaGen, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 3,
      "start_date": "2015-07",
      "completion_date": "2017-02-01",
      "has_results": false,
      "last_update_posted_date": "2023-02-21",
      "last_synced_at": "2026-06-10T10:41:58.948Z",
      "location_count": 6,
      "location_summary": "Oakland, California • Orange, California • Decatur, Georgia + 3 more",
      "locations": [
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Decatur",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02371226"
    },
    {
      "nct_id": "NCT03150069",
      "title": "Pregnancy With Morquio Syndrome - What Are Patients' Perspectives and Has ERT Changed Them?",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Morquio Disease",
        "MPS - Mucopolysaccharidosis"
      ],
      "interventions": [
        {
          "name": "Interview",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "100 Years",
        "sex": "FEMALE",
        "summary": "15 Years to 100 Years · Female only"
      },
      "enrollment_count": 18,
      "start_date": "2017-05-10",
      "completion_date": "2018-08-17",
      "has_results": false,
      "last_update_posted_date": "2021-01-20",
      "last_synced_at": "2026-06-10T10:41:58.948Z",
      "location_count": 1,
      "location_summary": "Decatur, Georgia",
      "locations": [
        {
          "city": "Decatur",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03150069"
    },
    {
      "nct_id": "NCT01870375",
      "title": "Longitudinal Studies of Brain Structure and Function in MPS Disorders",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mucopolysaccharidosis Type I",
        "Mucopolysaccharidosis Type II",
        "Mucopolysaccharidosis Type VI",
        "Mucopolysaccharidosis Type IV",
        "Mucopolysaccharidosis Type VII"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "6 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2009-09",
      "completion_date": "2019-08-31",
      "has_results": false,
      "last_update_posted_date": "2019-09-06",
      "last_synced_at": "2026-06-10T10:41:58.948Z",
      "location_count": 3,
      "location_summary": "Oakland, California • Minneapolis, Minnesota • New York, New York",
      "locations": [
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01870375"
    },
    {
      "nct_id": "NCT02060526",
      "title": "Randomized, Controlled, Open-label, Multicenter, Safety and Efficacy Study of rhHNS Administration Via an IDDD in Pediatric Patients With Early Stage MPS IIIA Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Sanfilippo Syndrome"
      ],
      "interventions": [
        {
          "name": "Recombinant human heparan N-sulfatase [rhHNS]",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Shire",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Months",
        "maximum_age": "48 Months",
        "sex": "ALL",
        "summary": "12 Months to 48 Months"
      },
      "enrollment_count": 21,
      "start_date": "2014-02-26",
      "completion_date": "2016-06-01",
      "has_results": true,
      "last_update_posted_date": "2021-06-08",
      "last_synced_at": "2026-06-10T10:41:58.948Z",
      "location_count": 3,
      "location_summary": "Torrance, California • Minneapolis, Minnesota • Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02060526"
    },
    {
      "nct_id": "NCT00786968",
      "title": "Extension Study of Intrathecal Enzyme Replacement Therapy for MPS I",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Spinal Cord Compression",
        "Mucopolysaccharidosis I",
        "Hurler-Scheie Syndrome",
        "Scheie Syndrome",
        "Lysosomal Storage Disease"
      ],
      "interventions": [
        {
          "name": "laronidase",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Patricia I. Dickson, M.D.",
      "sponsor_class": "INDIV",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "8 Years and older"
      },
      "enrollment_count": 3,
      "start_date": "2008-01",
      "completion_date": "2011-10",
      "has_results": false,
      "last_update_posted_date": "2013-02-21",
      "last_synced_at": "2026-06-10T10:41:58.948Z",
      "location_count": 1,
      "location_summary": "Torrance, California",
      "locations": [
        {
          "city": "Torrance",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00786968"
    },
    {
      "nct_id": "NCT04976231",
      "title": "MPS II Immunophenotyping",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "MPS II",
        "Mucopolysaccharidosis II",
        "Hunter Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 6,
      "start_date": "2022-04-01",
      "completion_date": "2024-04-26",
      "has_results": false,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-06-10T10:41:58.948Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04976231"
    },
    {
      "nct_id": "NCT01586871",
      "title": "Carotid Structure and Function in MPS Syndromes: A Multicenter Study of the Lysosomal Disease Network",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mucopolysaccharidoses"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "3 Years to 18 Years"
      },
      "enrollment_count": 1147,
      "start_date": "2012-03",
      "completion_date": "2017-06",
      "has_results": true,
      "last_update_posted_date": "2021-02-24",
      "last_synced_at": "2026-06-10T10:41:58.948Z",
      "location_count": 2,
      "location_summary": "Orange, California • Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01586871"
    },
    {
      "nct_id": "NCT01733615",
      "title": "Discovering New Biomarkers For Monitoring Disease Progression in Patients With Mucopolysaccharidosis IVA",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mucopolysaccharidosis Type IVA"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 3,
      "start_date": "2012-06",
      "completion_date": "2013-02",
      "has_results": false,
      "last_update_posted_date": "2014-09-04",
      "last_synced_at": "2026-06-10T10:41:58.948Z",
      "location_count": 1,
      "location_summary": "Decatur, Georgia",
      "locations": [
        {
          "city": "Decatur",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01733615"
    }
  ]
}