{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Mucopolysaccharidosis+Type+I&page=2", "query": { "condition": "Mucopolysaccharidosis Type I", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Mucopolysaccharidosis+Type+I&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-07-22T03:37:17.388Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01586455", "title": "Human Placental-Derived Stem Cell Transplantation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Mucopolysaccharidosis I", "Mucopolysaccharidosis VI", "Adrenoleukodystrophy", "Niemann-Pick Disease", "Metachromatic Leukodystrophy", "Wolman Disease", "Krabbe's Disease", "Gaucher's Disease", "Fucosidosis", "Batten Disease", "Severe Aplastic Anemia", "Diamond-Blackfan Anemia", "Amegakaryocytic Thrombocytopenia", "Myelodysplastic Syndrome", "Acute Myelogenous Leukemia", "Acute Lymphocytic Leukemia" ], "interventions": [ { "name": "Human Placental Derived Stem Cell", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "New York Medical College", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "0 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "0 Years to 55 Years" }, "enrollment_count": 43, "start_date": "2013-04", "completion_date": "2022-09", "has_results": false, "last_update_posted_date": "2022-10-25", "last_synced_at": "2026-07-22T03:37:17.388Z", "location_count": 3, "location_summary": "Denver, Colorado • Valhalla, New York • Salt Lake City, Utah", "locations": [ { "city": "Denver", "state": "Colorado" }, { "city": "Valhalla", "state": "New York" }, { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT01586455" }, { "nct_id": "NCT01917708", "title": "Bone Marrow Transplant With Abatacept for Non-Malignant Diseases", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Hurler Syndrome", "Fanconi Anemia", "Glanzmann Thrombasthenia", "Wiskott-Aldrich Syndrome", "Chronic Granulomatous Disease", "Severe Congenital Neutropenia", "Leukocyte Adhesion Deficiency", "Shwachman-Diamond Syndrome", "Diamond-Blackfan Anemia", "Dyskeratosis-congenita", "Chediak-Higashi Syndrome", "Severe Aplastic Anemia", "Thalassemia Major", "Hemophagocytic Lymphohistiocytosis", "Sickle Cell Disease" ], "interventions": [ { "name": "Abatacept", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Emory University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "21 Years", "sex": "ALL", "summary": "Up to 21 Years" }, "enrollment_count": 10, "start_date": "2014-01", "completion_date": "2019-09-19", "has_results": false, "last_update_posted_date": "2019-12-26", "last_synced_at": "2026-07-22T03:37:17.388Z", "location_count": 1, "location_summary": "Atlanta, Georgia", "locations": [ { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT01917708" }, { "nct_id": "NCT02171104", "title": "MT2013-31: Allo HCT for Metabolic Disorders and Severe Osteopetrosis", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Mucopolysaccharidosis Disorders", "Hurler Syndrome", "Hunter Syndrome", "Maroteaux Lamy Syndrome", "Sly Syndrome", "Alpha-Mannosidosis", "Fucosidosis", "Aspartylglucosaminuria", "Glycoprotein Metabolic Disorders", "Sphingolipidoses", "Recessive Leukodystrophies", "Globoid Cell Leukodystrophy", "Metachromatic Leukodystrophy", "Niemann-Pick B", "Niemann-Pick C Subtype 2", "Sphingomyelin Deficiency", "Peroxisomal Disorders", "Adrenoleukodystrophy With Cerebral Involvement", "Zellweger Syndrome", "Neonatal Adrenoleukodystrophy", "Infantile Refsum Disease", "Acyl-CoA Oxidase Deficiency", "D-Bifunctional Enzyme Deficiency", "Multifunctional Enzyme Deficiency", "Alpha-methylacyl-CoA Racmase Deficiency", "Mitochondrial Neurogastrointestingal Encephalopathy", "Severe Osteopetrosis", "Hereditary Leukoencephalopathy With Axonal Spheroids (HDLS; CSF1R Mutation)", "Inherited Metabolic Disorders" ], "interventions": [ { "name": "Stem Cell Transplantation", "type": "BIOLOGICAL" }, { "name": "IMD Preparative Regimen", "type": "DRUG" }, { "name": "Osteopetrosis Only Preparative Regimen", "type": "DRUG" }, { "name": "Osteopetrosis Haploidentical Only Preparative Regimen", "type": "DRUG" }, { "name": "cALD SR-A (Standard-Risk, Regimen A)", "type": "DRUG" }, { "name": "cALD SR-B (Standard-Risk, Regimen B)", "type": "DRUG" }, { "name": "cALD HR-D (High-Risk, Regimen C)", "type": "DRUG" }, { "name": "cALD HR-D (High-Risk, Regimen D)", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "Masonic Cancer Center, University of Minnesota", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "55 Years", "sex": "ALL", "summary": "Up to 55 Years" }, "enrollment_count": 149, "start_date": "2014-07-10", "completion_date": "2029-07-14", "has_results": false, "last_update_posted_date": "2026-01-07", "last_synced_at": "2026-07-22T03:37:17.388Z", "location_count": 1, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT02171104" }, { "nct_id": "NCT01938014", "title": "Lysosomal Storage Disease: Health, Development, and Functional Outcome Surveillance in Preschool Children", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Mucopolysaccharidosis Type I (MPS I)", "Mucopolysaccharidosis Type II (MPS II)", "Mucopolysaccharidosis Type III (MPS III)", "Mucopolysaccharidosis Type VI (MPS VI)", "Krabbe Disease" ], "interventions": [], "intervention_types": [], "sponsor": "University of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Day", "maximum_age": "18 Years", "sex": "ALL", "summary": "1 Day to 18 Years" }, "enrollment_count": 19, "start_date": "2009-01", "completion_date": "2016-07-23", "has_results": false, "last_update_posted_date": "2019-10-04", "last_synced_at": "2026-07-22T03:37:17.388Z", "location_count": 3, "location_summary": "Chicago, Illinois • Minneapolis, Minnesota • Buffalo, New York", "locations": [ { "city": "Chicago", "state": "Illinois" }, { "city": "Minneapolis", "state": "Minnesota" }, { "city": "Buffalo", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01938014" }, { "nct_id": "NCT03406962", "title": "MGTA-456 in Patients With Inherited Metabolic Disorders Undergoing Hematopoietic Stem Cell Transplantation (HSCT)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Inherited Metabolic Disorders (IMD)" ], "interventions": [ { "name": "MGTA-456", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Magenta Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "0 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "0 Years to 17 Years" }, "enrollment_count": 8, "start_date": "2018-02-09", "completion_date": "2021-01-15", "has_results": true, "last_update_posted_date": "2021-11-03", "last_synced_at": "2026-07-22T03:37:17.388Z", "location_count": 2, "location_summary": "Minneapolis, Minnesota • Cincinnati, Ohio", "locations": [ { "city": "Minneapolis", "state": "Minnesota" }, { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT03406962" }, { "nct_id": "NCT01675674", "title": "Study to Detect Unrecognized Mucopolysaccharidosis in Children Visiting Rheumatology, Hand or Skeletal Dysplasia Clinics", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Mucopolysaccharidoses", "Mucopolysaccharidosis I", "Mucopolysaccharidosis II", "Mucopolysaccharidosis IV", "Mucopolysaccharidosis VI" ], "interventions": [ { "name": "Dried blood spot test for MPS", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "National MPS Society", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Months", "maximum_age": "18 Years", "sex": "ALL", "summary": "6 Months to 18 Years" }, "enrollment_count": 3000, "start_date": "2011-09", "completion_date": "2014-03", "has_results": false, "last_update_posted_date": "2013-05-24", "last_synced_at": "2026-07-22T03:37:17.388Z", "location_count": 2, "location_summary": "New Brunswick, New Jersey • New York, New York", "locations": [ { "city": "New Brunswick", "state": "New Jersey" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01675674" }, { "nct_id": "NCT01572636", "title": "Laronidase (Aldurazyme TM) Enzyme Replacement Therapy With Hematopoietic Stem Cell Transplant for Hurler Syndrome", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Mucopolysaccharidosis Type IH", "MPS I", "Hurler Syndrome" ], "interventions": [ { "name": "Laronidase", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Masonic Cancer Center, University of Minnesota", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 20, "start_date": "2012-03-28", "completion_date": "2018-05-01", "has_results": false, "last_update_posted_date": "2018-09-27", "last_synced_at": "2026-07-22T03:37:17.388Z", "location_count": 1, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT01572636" }, { "nct_id": "NCT05619900", "title": "Registry of Patients Diagnosed With Lysosomal Storage Diseases", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Mucopolysaccharidosis I", "Mucopolysaccharidosis II", "Mucopolysaccharidosis IV A", "Mucopolysaccharidosis VI", "Mucopolysaccharidosis VII", "Pompe Disease Infantile-Onset", "Neuronopathic Gaucher Disease", "Wolman Disease" ], "interventions": [ { "name": "There is no intervention", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "64 Years", "sex": "ALL", "summary": "Up to 64 Years" }, "enrollment_count": 250, "start_date": "2022-05-31", "completion_date": "2050-05-31", "has_results": false, "last_update_posted_date": "2026-04-08", "last_synced_at": "2026-07-22T03:37:17.388Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05619900" }, { "nct_id": "NCT00215527", "title": "Intrathecal Enzyme Replacement Therapy for Spinal Cord Compression in Mucopolysaccharidosis (MPS) I", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Mucopolysaccharidosis I", "Lysosomal Storage Diseases", "Spinal Cord Compression" ], "interventions": [ { "name": "laronidase", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Patricia I. Dickson, M.D.", "sponsor_class": "INDIV", "healthy_volunteers": false, "eligibility": { "minimum_age": "8 Years", "maximum_age": null, "sex": "ALL", "summary": "8 Years and older" }, "enrollment_count": 4, "start_date": "2005-11", "completion_date": "2011-10", "has_results": false, "last_update_posted_date": "2013-02-21", "last_synced_at": "2026-07-22T03:37:17.388Z", "location_count": 1, "location_summary": "Torrance, California", "locations": [ { "city": "Torrance", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00215527" }, { "nct_id": "NCT00144794", "title": "Mucopolysaccharidosis I (MPS I) Registry", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Mucopolysaccharidosis I (MPS I)" ], "interventions": [], "intervention_types": [], "sponsor": "Genzyme, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 1406, "start_date": "2003-11-20", "completion_date": "2024-12-31", "has_results": false, "last_update_posted_date": "2026-02-27", "last_synced_at": "2026-07-22T03:37:17.388Z", "location_count": 53, "location_summary": "Phoenix, Arizona • Little Rock, Arkansas • Los Angeles, California + 44 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Oakland", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00144794" } ] }