{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Multiple-drug+Resistance", "query": { "condition": "Multiple-drug Resistance" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 98, "total_pages": 10, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Multiple-drug+Resistance&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-07-23T05:15:15.614Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01392469", "title": "Pharmacokinetic Effects of QTI571 on Sildenafil and Bosentan in Pulmonary Arterial Hypertension Participants", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pulmonary Arterial Hypertension" ], "interventions": [ { "name": "Imatinib", "type": "DRUG" }, { "name": "Sildenafil", "type": "DRUG" }, { "name": "Bosentan", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 21, "start_date": "2011-04-20", "completion_date": "2012-10-25", "has_results": true, "last_update_posted_date": "2021-06-21", "last_synced_at": "2026-07-23T05:15:15.614Z", "location_count": 3, "location_summary": "Tampa, Florida • Weston, Florida • Mineola, New York", "locations": [ { "city": "Tampa", "state": "Florida" }, { "city": "Weston", "state": "Florida" }, { "city": "Mineola", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01392469" }, { "nct_id": "NCT02707861", "title": "Ibalizumab Plus Optimized Background Regimen in Treatment-Experienced Patients With Multi-Drug Resistant HIV-1", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "HIV" ], "interventions": [ { "name": "ibalizumab", "type": "DRUG" }, { "name": "Optimized Background Regimen", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "TaiMed Biologics Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 79, "start_date": "2016-03", "completion_date": "2018-11", "has_results": true, "last_update_posted_date": "2021-03-11", "last_synced_at": "2026-07-23T05:15:15.614Z", "location_count": 31, "location_summary": "Long Beach, California • Los Angeles, California • Palm Springs, California + 21 more", "locations": [ { "city": "Long Beach", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02707861" }, { "nct_id": "NCT03678883", "title": "9-ING-41 in Patients With Advanced Cancers", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Cancer", "Pancreatic Cancer", "Sarcoma", "Renal Cancer", "Refractory Cancer", "Refractory Neoplasm", "Refractory Non-Hodgkin Lymphoma", "Pancreatic Adenocarcinoma", "Resistant Cancer", "Neoplasm Metastasis", "Neoplasm of Bone", "Neoplasm, Breast", "Neoplasm of Lung", "Neoplasms,Colorectal", "Neoplasms Pancreatic", "Malignant Glioma", "Malignancies", "Malignancies Multiple", "Bone Metastases", "Bone Neoplasm", "Bone Cancer", "Pancreas Cancer", "Pancreatic Neoplasms", "Breast Neoplasms", "Acute T Cell Leukemia Lymphoma" ], "interventions": [ { "name": "9-ING-41", "type": "DRUG" }, { "name": "Gemcitabine - 21 day cycle", "type": "DRUG" }, { "name": "Doxorubicin.", "type": "DRUG" }, { "name": "Lomustine", "type": "DRUG" }, { "name": "Carboplatin.", "type": "DRUG" }, { "name": "Nab paclitaxel.", "type": "DRUG" }, { "name": "Paclitaxel.", "type": "DRUG" }, { "name": "Gemcitabine - 28 day cycle", "type": "DRUG" }, { "name": "Irinotecan", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Actuate Therapeutics Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 350, "start_date": "2019-01-04", "completion_date": "2026-06", "has_results": false, "last_update_posted_date": "2026-04-03", "last_synced_at": "2026-07-23T05:15:15.614Z", "location_count": 40, "location_summary": "Phoenix, Arizona • Tucson, Arizona • Orange, California + 34 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Orange", "state": "California" }, { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03678883" }, { "nct_id": "NCT05303662", "title": "Prevalence of Multidrug Resistant Micro-organism Carriage in Patients Undergoing an ERCP in Four Different Countries", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Drug Resistance, Multiple, Bacterial", "Cholangiopancreatography, Endoscopic Retrograde" ], "interventions": [ { "name": "Multidrug-Resistant Organisms (MDRO) testing through rectal and oral/nasal swabs", "type": "DIAGNOSTIC_TEST" }, { "name": "MDRO-testing duodenal aspirate", "type": "DIAGNOSTIC_TEST" }, { "name": "Microbiome through rectal swab", "type": "DIAGNOSTIC_TEST" }, { "name": "Microbiome testing duodenal aspirate", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Marco J. Bruno", "sponsor_class": "OTHER", "healthy_volunteers": null, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1244, "start_date": "2022-01-31", "completion_date": "2024-12-30", "has_results": false, "last_update_posted_date": "2025-08-08", "last_synced_at": "2026-07-23T05:15:15.614Z", "location_count": 1, "location_summary": "Pittsburgh, Pennsylvania", "locations": [ { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT05303662" }, { "nct_id": "NCT00000796", "title": "A Prospective Study of Multidrug Resistance and a Pilot Study of the Safety of and Clinical and Microbiologic Response to Levofloxacin in Combination With Other Antimycobacterial Drugs for Treatment of Multidrug-Resistant Pulmonary Tuberculosis (MDRTB) in HIV-Infected Patients.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "HIV Infections", "Tuberculosis" ], "interventions": [ { "name": "Cycloserine", "type": "DRUG" }, { "name": "Ethionamide", "type": "DRUG" }, { "name": "Capreomycin sulfate", "type": "DRUG" }, { "name": "Aminosalicylic acid", "type": "DRUG" }, { "name": "Streptomycin sulfate", "type": "DRUG" }, { "name": "Ethambutol hydrochloride", "type": "DRUG" }, { "name": "Amikacin sulfate", "type": "DRUG" }, { "name": "Isoniazid", "type": "DRUG" }, { "name": "Pyrazinamide", "type": "DRUG" }, { "name": "Pyridoxine hydrochloride", "type": "DRUG" }, { "name": "Levofloxacin", "type": "DRUG" }, { "name": "Rifampin", "type": "DRUG" }, { "name": "Clofazimine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": null, "sex": "ALL", "summary": "13 Years and older" }, "enrollment_count": 525, "start_date": null, "completion_date": "1998-10", "has_results": false, "last_update_posted_date": "2021-11-03", "last_synced_at": "2026-07-23T05:15:15.614Z", "location_count": 21, "location_summary": "Chicago, Illinois • Detroit, Michigan • Brooklyn, New York + 2 more", "locations": [ { "city": "Chicago", "state": "Illinois" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Brooklyn", "state": "New York" }, { "city": "Brooklyn", "state": "New York" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00000796" }, { "nct_id": "NCT02824640", "title": "Patient-Centered Models of HCV Care for People Who Inject Drugs", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hepatitis C", "Medication Adherence" ], "interventions": [ { "name": "Patient Navigation", "type": "BEHAVIORAL" }, { "name": "modified Directly Observed Therapy", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Prisma Health-Upstate", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 755, "start_date": "2016-09-15", "completion_date": "2021-08-04", "has_results": true, "last_update_posted_date": "2024-09-26", "last_synced_at": "2026-07-23T05:15:15.614Z", "location_count": 1, "location_summary": "The Bronx, New York", "locations": [ { "city": "The Bronx", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02824640" }, { "nct_id": "NCT00001383", "title": "A Phase I Study of Infusional Paclitaxel With the P-Glycoprotein Antagonist PSC 833", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Breast Cancer", "Cancer", "Carcinoma, Renal Cell", "Lymphoma", "Ovarian Cancer" ], "interventions": [ { "name": "PSC 833", "type": "DRUG" }, { "name": "paclitaxel", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 52, "start_date": "1994-03", "completion_date": "2001-01", "has_results": false, "last_update_posted_date": "2008-03-04", "last_synced_at": "2026-07-23T05:15:15.614Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00001383" }, { "nct_id": "NCT03944369", "title": "VITORA: Clinical Study to Evaluate the Effect of KB109 on the Gut Microbiome in Subjects Whose Gastrointestinal Tracts Are Colonized With Multiple Drug-resistant Organisms", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Vancomycin-Resistant Enterococcus, Extended-Spectrum Beta Lactamase-Producing Enterobacteriaceae, or Carbapenem-Resistant Enterobacteriaceae Colonized Subjects" ], "interventions": [ { "name": "KB109", "type": "OTHER" }, { "name": "No intervention", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Kaleido Biosciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 3, "start_date": "2019-06-27", "completion_date": "2020-06-16", "has_results": false, "last_update_posted_date": "2021-01-22", "last_synced_at": "2026-07-23T05:15:15.614Z", "location_count": 8, "location_summary": "Torrance, California • Atlanta, Georgia • Augusta, Georgia + 5 more", "locations": [ { "city": "Torrance", "state": "California" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Augusta", "state": "Georgia" }, { "city": "Southfield", "state": "Michigan" }, { "city": "Stony Brook", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT03944369" }, { "nct_id": "NCT00389779", "title": "DORADO-AC - Optimized Doses of Darusentan as Compared to an Active Control in Resistant Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Darusentan", "type": "DRUG" }, { "name": "Guanfacine", "type": "DRUG" }, { "name": "Darusentan Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Gilead Sciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "35 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "35 Years to 80 Years" }, "enrollment_count": 849, "start_date": "2006-09", "completion_date": "2009-08", "has_results": false, "last_update_posted_date": "2014-03-18", "last_synced_at": "2026-07-23T05:15:15.614Z", "location_count": 87, "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Montgomery, Alabama + 70 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Montgomery", "state": "Alabama" }, { "city": "Glendale", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT00389779" }, { "nct_id": "NCT00868595", "title": "MTD Study of Vaccine BP-GMAX-CD1 Plus AP1903 to Treat Castrate Resistant Prostate Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Castrate Resistant Prostate Cancer (CRPC)" ], "interventions": [ { "name": "BPX-101", "type": "BIOLOGICAL" }, { "name": "AP1903", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "Bellicum Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "MALE", "summary": "18 Years and older · Male only" }, "enrollment_count": 18, "start_date": "2009-04", "completion_date": "2012-03", "has_results": false, "last_update_posted_date": "2019-10-08", "last_synced_at": "2026-07-23T05:15:15.614Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00868595" } ] }