{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Muscle+Rigidity",
    "query": {
      "condition": "Muscle Rigidity"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 19,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Muscle+Rigidity&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T11:41:27.790Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06785207",
      "title": "Rethinking Rigidity: Development of a 3D-Printed Scoliosis Brace With Varying Flexibility",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Scoliosis Idiopathic Adolescent Treatment"
      ],
      "interventions": [
        {
          "name": "3D-printed scoliosis brace",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "8 Years to 18 Years"
      },
      "enrollment_count": 5,
      "start_date": "2025-04-01",
      "completion_date": "2026-10-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-02",
      "last_synced_at": "2026-07-23T11:41:27.790Z",
      "location_count": 2,
      "location_summary": "Houston, Texas • The Woodlands, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "The Woodlands",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06785207"
    },
    {
      "nct_id": "NCT07226440",
      "title": "Examining a Novel Gastrointestinal Intervention to Negate Environmental Toxicants (ENGINE)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Toxicant Exposure",
        "Firefighter",
        "Occupational Exposure to Chemicals"
      ],
      "interventions": [
        {
          "name": "Colesevelam",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 50,
      "start_date": "2026-03-01",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-04-24",
      "last_synced_at": "2026-07-23T11:41:27.790Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07226440"
    },
    {
      "nct_id": "NCT01403402",
      "title": "Congenital Muscle Disease Study of Patient and Family Reported Medical Information",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Congenital Muscular Dystrophy With ITGA7 (Integrin Alpha-7) Deficiency",
        "Alpha-Dystroglycanopathy (Congenital Muscular Dystrophy and Abnormal Glycosylation of Dystroglycan With Severe Epilepsy)",
        "Alpha-Dystroglycanopathy (Congenital Muscular Dystrophy With Fatty Liver and Infantile-onset Cataract Caused by TRAPPC11 Mutations)",
        "Alpha-Dystroglycanopathy (Congenital Muscular Dystrophy With Hypoglycosylation of Dystroglycan)",
        "Alpha-Dystroglycanopathy (Congenital Muscular Dystrophy With Hypoglycosylation of Dystroglycan and Epilepsy)",
        "Alpha-Dystroglycanopathy (Dystroglycanopathy, Congenital With or Without Mental Retardation (Formerly MDC1C))",
        "Alpha-Dystroglycanopathy (Fukuyama CMD)",
        "Alpha-Dystroglycanopathy (LGMDR09 FKRP Related (Formerly LGMD2I))",
        "Alpha-Dystroglycanopathy (LGMDR11 POMT1 Related (Formerly LGMD2K))",
        "Alpha-Dystroglycanopathy (LGMDR13 FKTN Related (Formerly LGMD2M))",
        "Alpha-Dystroglycanopathy (LGMDR14 POMT2 Related (Formerly LGMD2N))",
        "Alpha-Dystroglycanopathy (LGMDR15 POMGnT1 Related (Formerly LGMD2O))",
        "Alpha-Dystroglycanopathy (LGMDR19 GMPPB Related (Formerly LGMD2T))",
        "Alpha-Dystroglycanopathy (LGMDR20 ISPD Related (Formerly LGMD2U))",
        "Alpha-Dystroglycanopathy (LGMDR24 POMGnT2 Related)",
        "Alpha-Dystroglycanopathy (Muscle Eye Brain Disease (MEB))",
        "Alpha-Dystroglycanopathy (Walker Warburg Syndrome (WWS))",
        "Choline Kinase B Receptor - CHKB",
        "Collagen VI Related Disorders",
        "Collagen XII Related Disorders",
        "Congenital Muscular Dystrophy Not Otherwise Specified (Including Merosin Positive)",
        "Congenital Muscular Dystrophy With Cataracts and Intellectual Disability (MDCCAID)",
        "Congenital Muscular Dystrophy With Joint Hyperlaxity",
        "Congenital Muscular Dystrophy With Rigid Spine Related to ACTA1",
        "Emery-Dreifuss Muscular Dystrophy",
        "GOLGA2-related Congenital Muscle Dystrophy With Brain Involvement",
        "LMNA Related Disorders",
        "Merosin Deficient CMD (Full or Partial)",
        "Nesprin Related MD (SYNE1)",
        "SELENON Related Disorders (Previously Known as SEPN1)",
        "SELENON Related Myopathy (Aka SEPN1)",
        "Telethonin CMD",
        "Congenital Myasthenic Syndrome",
        "Limb-Girdle Muscular Dystrophy",
        "LGMDD01 - DNAJB6 (Formerly LGMD1D)",
        "LGMDD05 - Collagen VI Related Bethlem Myopathy (Dominant)",
        "LGMDR07 - Telethonin (TCAP) Related (Formerly LGMD2G)",
        "LGMDR08 - TRIM Related (Formerly LGMD2H)",
        "LGMDR09 - FKRP Related (Formerly LGMD2I)",
        "LGMDR10 - Titin (TTN) Related (Formerly LGMD2J)",
        "LGMDR11 - POMT1 Related (Formerly LGMD2K)",
        "LGMDR13 - Fukutin (FKTN) Related (Formerly LGMD2M)",
        "LGMDR14 - POMT2 Related (Formerly LGMD2N)",
        "LGMDR15 - POMGnT1 Related (Formerly LGMD2O)",
        "LGMDR16 - DAG1 Related Dystroglycanopathy (Formerly LGMD2P)",
        "LGMDR17 - Plectin (PLEC) Related (Formerly LGMD2Q)",
        "LGMDR18 - TRAPPC11 Related (Formerly LGMD2S)",
        "LGMDR19 - GMPPB Related (Formerly LGMD2T)",
        "LGMDR20 - ISPD Related (Formerly LGMD2U)",
        "LGMDR22 - Collagen VI Related Bethlem Myopathy (Recessive)",
        "LGMDR23 - LAMA2 Related",
        "LGMDR24 - POMGnT2 Related"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Cure CMD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 4000,
      "start_date": "2009-09",
      "completion_date": "2029-09",
      "has_results": false,
      "last_update_posted_date": "2021-08-09",
      "last_synced_at": "2026-07-23T11:41:27.790Z",
      "location_count": 1,
      "location_summary": "Lakewood, California",
      "locations": [
        {
          "city": "Lakewood",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01403402"
    },
    {
      "nct_id": "NCT00472914",
      "title": "Use of EMG to Assess Clinical Hypertonia",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cerebral Palsy",
        "Hypertonia",
        "Spasticity",
        "Dystonia",
        "Rigidity"
      ],
      "interventions": [
        {
          "name": "portable surface electromyography",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "6 Years to 18 Years"
      },
      "enrollment_count": 14,
      "start_date": "2007-01",
      "completion_date": "2007-03",
      "has_results": false,
      "last_update_posted_date": "2014-05-23",
      "last_synced_at": "2026-07-23T11:41:27.790Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00472914"
    },
    {
      "nct_id": "NCT01718704",
      "title": "Viberect Penile Vibratory Stimulation to Enhance Recovery of Erectile Function and Urinary Continence Post-Prostatectomy",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Erectile Dysfunction Following Radical Prostatectomy",
        "Urinary Incontinence of Non-organic Origin"
      ],
      "interventions": [
        {
          "name": "Viberect device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "MALE",
        "summary": "40 Years to 70 Years · Male only"
      },
      "enrollment_count": 0,
      "start_date": "2013-04",
      "completion_date": "2019-03-27",
      "has_results": false,
      "last_update_posted_date": "2019-05-24",
      "last_synced_at": "2026-07-23T11:41:27.790Z",
      "location_count": 2,
      "location_summary": "Baltimore, Maryland • Frederick, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Frederick",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01718704"
    },
    {
      "nct_id": "NCT05736471",
      "title": "Cognitive and Affective Processes Online",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Depression"
      ],
      "interventions": [
        {
          "name": "Computational dissociation of the causes of cognitive rigidity in depression",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2500,
      "start_date": "2023-02-15",
      "completion_date": "2027-05-02",
      "has_results": false,
      "last_update_posted_date": "2026-05-19",
      "last_synced_at": "2026-07-23T11:41:27.790Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05736471"
    },
    {
      "nct_id": "NCT02282514",
      "title": "Stem Cell Transplantation for Stiff Person Syndrome (SPS)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Stiff-Person Syndrome"
      ],
      "interventions": [
        {
          "name": "Autologous Hematopoietic Stem Cells",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Cyclophosphamide",
          "type": "DRUG"
        },
        {
          "name": "Mesna",
          "type": "DRUG"
        },
        {
          "name": "rATG",
          "type": "DRUG"
        },
        {
          "name": "Methylprednisolone",
          "type": "DRUG"
        },
        {
          "name": "G-CSF",
          "type": "DRUG"
        },
        {
          "name": "Rituxan",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 23,
      "start_date": "2014-10",
      "completion_date": "2019-08-30",
      "has_results": true,
      "last_update_posted_date": "2021-01-27",
      "last_synced_at": "2026-07-23T11:41:27.790Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02282514"
    },
    {
      "nct_id": "NCT07182058",
      "title": "Virtual tES Device Treatment for Parkinson's Disease Motor Symptoms",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "PARKINSON DISEASE (Disorder)"
      ],
      "interventions": [
        {
          "name": "Transcranial Electrical Stimulation Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "U: The Mind Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 30,
      "start_date": "2026-01-01",
      "completion_date": "2026-04-01",
      "has_results": false,
      "last_update_posted_date": "2026-01-27",
      "last_synced_at": "2026-07-23T11:41:27.790Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07182058"
    },
    {
      "nct_id": "NCT00072800",
      "title": "Classification of Cerebral Palsy Subtypes",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cerebral Palsy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 115,
      "start_date": "2003-11",
      "completion_date": "2005-08",
      "has_results": false,
      "last_update_posted_date": "2008-03-04",
      "last_synced_at": "2026-07-23T11:41:27.790Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00072800"
    },
    {
      "nct_id": "NCT03111121",
      "title": "Use of Sugammadex for Reversal of Paralysis in Microlaryngoscopy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Microlaryngoscopy",
        "Rigid Bronchoscopy"
      ],
      "interventions": [
        {
          "name": "Sugammadex",
          "type": "DRUG"
        },
        {
          "name": "neostigmine",
          "type": "DRUG"
        },
        {
          "name": "glycopyrrolate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "West Virginia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 79,
      "start_date": "2017-05-04",
      "completion_date": "2019-05-30",
      "has_results": true,
      "last_update_posted_date": "2025-07-20",
      "last_synced_at": "2026-07-23T11:41:27.790Z",
      "location_count": 1,
      "location_summary": "Morgantown, West Virginia",
      "locations": [
        {
          "city": "Morgantown",
          "state": "West Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03111121"
    }
  ]
}