{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Muscle+Tone",
    "query": {
      "condition": "Muscle Tone"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 54,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Muscle+Tone&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T04:09:34.908Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04426526",
      "title": "HIFEM for Arms, Lower Limbs, and Oblique Muscles",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Muscle Tone Increased"
      ],
      "interventions": [
        {
          "name": "BTL 799-2",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "BTL Industries Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 23,
      "start_date": "2019-05-08",
      "completion_date": "2020-12-08",
      "has_results": false,
      "last_update_posted_date": "2021-01-13",
      "last_synced_at": "2026-06-11T04:09:34.908Z",
      "location_count": 2,
      "location_summary": "Fort Collins, Colorado • New York, New York",
      "locations": [
        {
          "city": "Fort Collins",
          "state": "Colorado"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04426526"
    },
    {
      "nct_id": "NCT06724146",
      "title": "Combined Treatment Sofwave and Pure Impact to Strength and Tone Muscles and Improve Lax Skin Appearance",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Skin Lax and Muscle Strength"
      ],
      "interventions": [
        {
          "name": "Sofwave and Pure Impact",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Sofwave Medical LTD",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "25 Years to 70 Years"
      },
      "enrollment_count": 70,
      "start_date": "2024-08-05",
      "completion_date": "2026-11-01",
      "has_results": false,
      "last_update_posted_date": "2024-12-09",
      "last_synced_at": "2026-06-11T04:09:34.908Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06724146"
    },
    {
      "nct_id": "NCT07094971",
      "title": "Pure Impact Treatment to Strengthen and Tone Abdomen, Quadriceps and Glutes Muscles",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Muscle Tone",
        "Muscle Strength"
      ],
      "interventions": [
        {
          "name": "Pure Impact",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Sofwave Medical LTD",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "25 Years to 60 Years"
      },
      "enrollment_count": 44,
      "start_date": "2025-07-11",
      "completion_date": "2026-07-10",
      "has_results": false,
      "last_update_posted_date": "2025-08-03",
      "last_synced_at": "2026-06-11T04:09:34.908Z",
      "location_count": 1,
      "location_summary": "Eugene, Oregon",
      "locations": [
        {
          "city": "Eugene",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07094971"
    },
    {
      "nct_id": "NCT01127399",
      "title": "Bariatric and Obstructive Lung Disease Study II",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Obesity",
        "Asthma"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2009-09",
      "completion_date": "2011-06",
      "has_results": false,
      "last_update_posted_date": "2018-02-05",
      "last_synced_at": "2026-06-11T04:09:34.908Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01127399"
    },
    {
      "nct_id": "NCT03814889",
      "title": "Passive Tactile Stimulation for Stroke Rehabilitation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stroke",
        "Stroke, Ischemic",
        "Stroke Hemorrhagic",
        "Spasticity as Sequela of Stroke"
      ],
      "interventions": [
        {
          "name": "Vibration pattern",
          "type": "DEVICE"
        },
        {
          "name": "No vibration",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 35,
      "start_date": "2019-05-15",
      "completion_date": "2022-12-31",
      "has_results": true,
      "last_update_posted_date": "2024-04-08",
      "last_synced_at": "2026-06-11T04:09:34.908Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03814889"
    },
    {
      "nct_id": "NCT04851730",
      "title": "The Effect of an Individualized Impairment-based, Orthopedic Physical Therapy Intervention (IOI), on Muscle Stiffness, Pelvic Floor Function, and Pain in Women With Chronic Pelvic Pain",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pelvic Pain",
        "Chronic Pain",
        "Muscle Tightness"
      ],
      "interventions": [
        {
          "name": "Orthopedic Physical Therapy Intervention",
          "type": "PROCEDURE"
        },
        {
          "name": "Dry Needling",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Texas Woman's University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 15,
      "start_date": "2021-04-12",
      "completion_date": "2021-07-01",
      "has_results": false,
      "last_update_posted_date": "2021-04-20",
      "last_synced_at": "2026-06-11T04:09:34.908Z",
      "location_count": 1,
      "location_summary": "Lee's Summit, Missouri",
      "locations": [
        {
          "city": "Lee's Summit",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04851730"
    },
    {
      "nct_id": "NCT06970522",
      "title": "Wearable Sensors to Detect Atypical Muscle Activation in Young Infants",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Neuromuscular Disorders",
        "Motor Development",
        "Muscle Tone"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Shirley Ryan AbilityLab",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Months",
        "maximum_age": "8 Weeks",
        "sex": "ALL",
        "summary": "0 Months to 8 Weeks"
      },
      "enrollment_count": 40,
      "start_date": "2025-06-25",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-25",
      "last_synced_at": "2026-06-11T04:09:34.908Z",
      "location_count": 2,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06970522"
    },
    {
      "nct_id": "NCT02074150",
      "title": "ASIS for Botox in Upper Limb Spasticity",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Upper Limb Spasticity Unilaterally in Adults With History of Stroke",
        "Increased Muscle Tone in Elbow, Wrist, Finger, and Thumb Flexors."
      ],
      "interventions": [
        {
          "name": "Gadolinium",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox intramuscularly at Week 6",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox intramuscularly at Week 12,",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox intramuscularly at Week 18",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox intramuscularly at Week 24",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox intramuscularly at Week 30",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox subdermally at Week 6",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox subdermally at Week 12",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox subdermally at Week 18",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox subdermally at Week 24",
          "type": "DRUG"
        },
        {
          "name": "Efficacy of Botox subdermally at Week 30",
          "type": "DRUG"
        },
        {
          "name": "Adverse Reactions of Botox intramuscularly",
          "type": "DRUG"
        },
        {
          "name": "Adverse Reactions of Botox subdermally",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "li nguyen",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 60,
      "start_date": "2016-01",
      "completion_date": "2017-06",
      "has_results": false,
      "last_update_posted_date": "2015-06-24",
      "last_synced_at": "2026-06-11T04:09:34.908Z",
      "location_count": 1,
      "location_summary": "Westminster, California",
      "locations": [
        {
          "city": "Westminster",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02074150"
    },
    {
      "nct_id": "NCT03410797",
      "title": "Efficacy of a Semi-occluded Mask in the Treatment of Patients With Voice Disorders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Voice and Resonance Disorders",
        "Vocal Fold Polyp",
        "Vocal Cord Cyst",
        "Vocal Cord Polyp",
        "Atrophy of Vocal Cord"
      ],
      "interventions": [
        {
          "name": "Inclusion of semi-occluded mask in voice therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Jacqueline Gartner-Schmidt",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 11,
      "start_date": "2018-06-19",
      "completion_date": "2019-12-30",
      "has_results": true,
      "last_update_posted_date": "2021-01-05",
      "last_synced_at": "2026-06-11T04:09:34.908Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03410797"
    },
    {
      "nct_id": "NCT01856972",
      "title": "Does the Addition of Manual Therapy Techniques Increase Gastrocnemius/Soleus Length More Than Stretching Alone?",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Muscle Tightness"
      ],
      "interventions": [
        {
          "name": "Instrument Assisted Soft Tissue Mobilization",
          "type": "PROCEDURE"
        },
        {
          "name": "Rearfoot joint mobilization",
          "type": "PROCEDURE"
        },
        {
          "name": "Static stretching/ROM exercises",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Nationwide Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2013-05",
      "completion_date": "2014-06",
      "has_results": false,
      "last_update_posted_date": "2014-06-11",
      "last_synced_at": "2026-06-11T04:09:34.908Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01856972"
    }
  ]
}