{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Muscular+Weakness",
    "query": {
      "condition": "Muscular Weakness"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 203,
    "total_pages": 21,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Muscular+Weakness&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T07:37:44.198Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00549458",
      "title": "Randomized Controlled Trial Comparing Traditional Pelvic Floor Rehabilitation to Pilates in Increasing Pelvic Muscles Strength.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Muscle Weakness"
      ],
      "interventions": [
        {
          "name": "Pilates",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pelvic muscle rehabilitation therapy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "PROCEDURE"
      ],
      "sponsor": "Atlantic Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2006-04",
      "completion_date": "2009-03",
      "has_results": false,
      "last_update_posted_date": "2009-09-18",
      "last_synced_at": "2026-07-22T07:37:44.198Z",
      "location_count": 1,
      "location_summary": "Morristown, New Jersey",
      "locations": [
        {
          "city": "Morristown",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00549458"
    },
    {
      "nct_id": "NCT03701568",
      "title": "A RETROspective Study of Patients With TK2d",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Thymidine Kinase 2 (TK2)"
      ],
      "interventions": [
        {
          "name": "dC/dT",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Zogenix MDS, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 38,
      "start_date": "2018-11-19",
      "completion_date": "2019-05-31",
      "has_results": false,
      "last_update_posted_date": "2023-09-01",
      "last_synced_at": "2026-07-22T07:37:44.198Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03701568"
    },
    {
      "nct_id": "NCT06143228",
      "title": "Influence of Directional Preference on Movement Coordination Deficits in Individuals With Whiplash Associated Disorders",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Whiplash Injury of Cervical Spine",
        "Muscle Weakness"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "D'Youville College",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "19 Years to 70 Years"
      },
      "enrollment_count": 65,
      "start_date": "2023-12-30",
      "completion_date": "2024-12-30",
      "has_results": false,
      "last_update_posted_date": "2024-02-22",
      "last_synced_at": "2026-07-22T07:37:44.198Z",
      "location_count": 2,
      "location_summary": "Tallahassee, Florida • Tampa, Florida",
      "locations": [
        {
          "city": "Tallahassee",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06143228"
    },
    {
      "nct_id": "NCT04234282",
      "title": "Rate of Torque Development and Voluntary Quadriceps Activation in Patients With Knee Osteoarthritis: A Quantitative Analysis Before and After a Single Session of Manual Physical Therapy",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Osteoarthritis",
        "Knee Arthritis",
        "Knee Pain Chronic",
        "Knee Deformity",
        "Knee Pain Swelling",
        "Muscle Weakness",
        "Muscle Weakness Condition",
        "Power"
      ],
      "interventions": [
        {
          "name": "Manual Physical Therapy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Jennifer Moreno Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "74 Years",
        "sex": "ALL",
        "summary": "45 Years to 74 Years"
      },
      "enrollment_count": 40,
      "start_date": "2020-01",
      "completion_date": "2020-07",
      "has_results": false,
      "last_update_posted_date": "2020-01-21",
      "last_synced_at": "2026-07-22T07:37:44.198Z",
      "location_count": 1,
      "location_summary": "Fort Sam Houston, Texas",
      "locations": [
        {
          "city": "Fort Sam Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04234282"
    },
    {
      "nct_id": "NCT06129110",
      "title": "Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Insulin Sensitivity",
        "Muscle Weakness",
        "Adiposity",
        "Insulin Resistance"
      ],
      "interventions": [
        {
          "name": "Diet Weight Loss",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 70,
      "start_date": "2024-01-31",
      "completion_date": "2028-09-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-15",
      "last_synced_at": "2026-07-22T07:37:44.198Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06129110"
    },
    {
      "nct_id": "NCT02367170",
      "title": "Project 4A: Inspiratory Muscle Training and Diaphragm Strength",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Sepsis"
      ],
      "interventions": [
        {
          "name": "Bilateral phrenic nerve stimulation and measurement of transdiaphragmatic pressure",
          "type": "PROCEDURE"
        },
        {
          "name": "Midazolam",
          "type": "DRUG"
        },
        {
          "name": "Volitional Measurement of Maximal Inspiratory Pressure (MIP)",
          "type": "PROCEDURE"
        },
        {
          "name": "Inspiratory Muscle Strength Training (IMST)",
          "type": "DEVICE"
        },
        {
          "name": "SHAM Inspiratory Muscle Strength Training (IMST)",
          "type": "DEVICE"
        },
        {
          "name": "Diaphragm thickness measurement",
          "type": "PROCEDURE"
        },
        {
          "name": "Blood and Urine samples",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG",
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1,
      "start_date": "2015-03",
      "completion_date": "2015-07",
      "has_results": true,
      "last_update_posted_date": "2018-05-07",
      "last_synced_at": "2026-07-22T07:37:44.198Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02367170"
    },
    {
      "nct_id": "NCT00715494",
      "title": "A Pilot Study of Rehabilitation Among Intensive Care Unit (ICU) Survivors: the RETURN Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Brain Injury",
        "Muscle Weakness"
      ],
      "interventions": [
        {
          "name": "Cognitive, physical, and functional rehabilitation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 24,
      "start_date": "2008-07",
      "completion_date": "2015-12",
      "has_results": false,
      "last_update_posted_date": "2018-09-11",
      "last_synced_at": "2026-07-22T07:37:44.198Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00715494"
    },
    {
      "nct_id": "NCT03359473",
      "title": "Study to Evaluate the Safety and Efficacy of 13 Weeks of the Selective Androgen Receptor Modulator (SARM) GSK2881078 in Chronic Obstructive Pulmonary Disease (COPD)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cachexia"
      ],
      "interventions": [
        {
          "name": "GSK2881078",
          "type": "DRUG"
        },
        {
          "name": "Matching Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "50 Years to 75 Years"
      },
      "enrollment_count": 97,
      "start_date": "2018-02-28",
      "completion_date": "2019-11-19",
      "has_results": true,
      "last_update_posted_date": "2020-07-15",
      "last_synced_at": "2026-07-22T07:37:44.198Z",
      "location_count": 5,
      "location_summary": "Torrance, California • Jacksonville, Florida • High Point, North Carolina + 2 more",
      "locations": [
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "High Point",
          "state": "North Carolina"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Spartanburg",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03359473"
    },
    {
      "nct_id": "NCT05460637",
      "title": "Physical Activity Intervention Tailored for Rural Men",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Physical Inactivity",
        "Sedentary Behavior",
        "Weak; Muscle"
      ],
      "interventions": [
        {
          "name": "No BS just Fitness",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Jacob Gallagher",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "MALE",
        "summary": "18 Years to 80 Years · Male only"
      },
      "enrollment_count": 40,
      "start_date": "2022-08-01",
      "completion_date": "2023-01-20",
      "has_results": false,
      "last_update_posted_date": "2023-02-21",
      "last_synced_at": "2026-07-22T07:37:44.198Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05460637"
    },
    {
      "nct_id": "NCT00125658",
      "title": "Mechanisms of Upper-Extremity Motor Recovery in Post-stroke Hemiparesis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cerebrovascular Accident"
      ],
      "interventions": [
        {
          "name": "Control",
          "type": "OTHER"
        },
        {
          "name": "Experimental",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 14,
      "start_date": "2008-02",
      "completion_date": "2011-09",
      "has_results": true,
      "last_update_posted_date": "2017-06-23",
      "last_synced_at": "2026-07-22T07:37:44.198Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00125658"
    }
  ]
}