{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Myalgic+Encephalomyelitis+%28ME%29&page=2",
    "query": {
      "condition": "Myalgic Encephalomyelitis (ME)",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Myalgic+Encephalomyelitis+%28ME%29&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T06:13:56.514Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02948556",
      "title": "ME/CFS: Activity Patterns and Autonomic Dysfunction",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Fatigue Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Stony Brook University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 150,
      "start_date": "2016-06",
      "completion_date": "2020-05",
      "has_results": false,
      "last_update_posted_date": "2016-11-03",
      "last_synced_at": "2026-06-10T06:13:56.514Z",
      "location_count": 1,
      "location_summary": "Stony Brook, New York",
      "locations": [
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02948556"
    },
    {
      "nct_id": "NCT01966276",
      "title": "The Synergy Trial: Methylphenidate Plus a CFS-Specific Nutrient Formula as a Treatment for Chronic Fatigue Syndrome",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Chronic Fatigue Syndrome (CFS)",
        "Myalgic Encephalomyelitis (ME)"
      ],
      "interventions": [
        {
          "name": "Methyl-P plus Nutrient Formula",
          "type": "DRUG"
        },
        {
          "name": "Methyl-P plus Nutrient matched placebos",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "K-PAX Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "59 Years",
        "sex": "ALL",
        "summary": "18 Years to 59 Years"
      },
      "enrollment_count": 134,
      "start_date": "2013-11",
      "completion_date": "2014-12",
      "has_results": false,
      "last_update_posted_date": "2014-09-25",
      "last_synced_at": "2026-06-10T06:13:56.514Z",
      "location_count": 4,
      "location_summary": "Stanford, California • Fort Lauderdale, Florida • New York, New York + 1 more",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Fort Lauderdale",
          "state": "Florida"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01966276"
    },
    {
      "nct_id": "NCT04806620",
      "title": "Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Post-Acute COVID-19 Syndrome",
        "ME/CFS",
        "Rheumatic Arthritis",
        "Juvenile Rheumatoid Arthritis (JRA)",
        "Psoriatic Arthritis (PsA)",
        "Ankylosing Spondylitis (AS)",
        "Autoimmune Encephalitis",
        "Celiac Disease",
        "Celiac Disease in Children",
        "Chronic Lyme Disease",
        "Post-treatment Lyme Disease Syndrome",
        "Crohn's Disease",
        "Dysautonomia",
        "Anorexia Nervosa",
        "Bulimia Nervosa",
        "ARFID",
        "Avoidant / Restrictive Food Intake Disorder",
        "Ehlers Danlos Syndrome",
        "Endometriosis",
        "Fibromyalgia (FM)",
        "Long COVID",
        "Lupus",
        "Migraines",
        "Mast Cell Activation Syndrome",
        "Multiple Sclerosis",
        "Myalgic Encephalomyelitis (ME)",
        "Myasthenia Gravis, Generalized",
        "Myasthenia Gravis in Children",
        "Narcolepsy",
        "Obsessive Compulsive Disorder (OCD)",
        "PANDAS",
        "Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)",
        "POTS - Postural Orthostatic Tachycardia Syndrome",
        "General Anxiety Disorder, Social Anxiety Disorder",
        "PTSD - Post Traumatic Stress Disorder",
        "Psoriasis",
        "Traumatic Brain Injury",
        "Tourette's Syndrome",
        "Inflammatory Bowel Disease (IBD)",
        "Autoimmune Diseases",
        "Neurological Diseases or Conditions",
        "Psychiatric Disorder",
        "Sjogren's Syndrome",
        "Ulcerative Colitis and Crohn's Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Brain Inflammation Collaborative",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "2 Years and older"
      },
      "enrollment_count": 10000,
      "start_date": "2023-07-05",
      "completion_date": "2030-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-01-22",
      "last_synced_at": "2026-06-10T06:13:56.514Z",
      "location_count": 1,
      "location_summary": "Delafield, Wisconsin",
      "locations": [
        {
          "city": "Delafield",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04806620"
    },
    {
      "nct_id": "NCT06227273",
      "title": "Hydrogen Water Dosing Study for ME/CFS",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome"
      ],
      "interventions": [
        {
          "name": "Hydrogen water",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Stony Brook University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 50,
      "start_date": "2023-12-01",
      "completion_date": "2024-11-30",
      "has_results": false,
      "last_update_posted_date": "2024-01-26",
      "last_synced_at": "2026-06-10T06:13:56.514Z",
      "location_count": 1,
      "location_summary": "Stony Brook, New York",
      "locations": [
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06227273"
    },
    {
      "nct_id": "NCT04100915",
      "title": "A Non-Interventional Pilot Study to Explore the Role of Gut Flora in ME/CFS",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Myalgic Encephalomyelitis",
        "Chronic Fatigue Syndrome"
      ],
      "interventions": [
        {
          "name": "No Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "ProgenaBiome",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2020-03-02",
      "completion_date": "2030-07",
      "has_results": false,
      "last_update_posted_date": "2025-06-05",
      "last_synced_at": "2026-06-10T06:13:56.514Z",
      "location_count": 1,
      "location_summary": "Ventura, California",
      "locations": [
        {
          "city": "Ventura",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04100915"
    },
    {
      "nct_id": "NCT05273372",
      "title": "RESTORE ME -- RCT of Oxaloacetate on Improving Fatigue in ME/CFS",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myalgic Encephalomyelitis",
        "Chronic Fatigue Syndrome",
        "Fatigue"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "OTHER"
        },
        {
          "name": "Medical Food - Anhydrous Enol-Oxaloacetate",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Terra Biological LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 82,
      "start_date": "2022-03-15",
      "completion_date": "2024-11-15",
      "has_results": false,
      "last_update_posted_date": "2025-02-04",
      "last_synced_at": "2026-06-10T06:13:56.514Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05273372"
    },
    {
      "nct_id": "NCT04542161",
      "title": "Assessment of N-Acetylcysteine as Therapy for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Chronic Fatigue Syndrome",
        "Myalgic Encephalomyelitis"
      ],
      "interventions": [
        {
          "name": "NAC 900mg/day",
          "type": "DRUG"
        },
        {
          "name": "NAC 3600mg/day",
          "type": "DRUG"
        },
        {
          "name": "NAC 0mg/day (Placebo)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 95,
      "start_date": "2020-09-01",
      "completion_date": "2026-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-02-25",
      "last_synced_at": "2026-06-10T06:13:56.514Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04542161"
    },
    {
      "nct_id": "NCT03952624",
      "title": "Patient-Centered Assessment of Symptoms and Outcomes",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Fatigue",
        "Cancer",
        "CFS",
        "ME/CFS",
        "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome",
        "Lupus",
        "Systemic Lupus Erthematosus",
        "Sjogrens"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Center for Complementary and Integrative Health (NCCIH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 692,
      "start_date": "2019-09-13",
      "completion_date": "2026-07-01",
      "has_results": false,
      "last_update_posted_date": "2026-06-08",
      "last_synced_at": "2026-06-10T06:13:56.514Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03952624"
    },
    {
      "nct_id": "NCT07523113",
      "title": "ME/CFS Brain Fog: Cognitive Rehabilitation Trial",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ME/CFS",
        "ME/CFS Following EBV-associated Infectious Mononucleosis",
        "ME/CFS Following COVID-19",
        "Chronic Fatigue",
        "Chronic Fatigue Syndrome (CFS)",
        "Brain Fog",
        "Cognitive Impairment",
        "Cognitive Dysfunction"
      ],
      "interventions": [
        {
          "name": "Processing Speed Training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "In-session Instrumental Activities of Daily Living Training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Transfer Package",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Follow Up Phone Calls",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Trans-auricular Vagus Nerve Stimulation: High Intensity",
          "type": "PROCEDURE"
        },
        {
          "name": "In-session Brain Health Training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Reaction Time Training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Trans-auricular Vagus Nerve Stimulation: Low Intensity",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "PROCEDURE"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2026-06",
      "completion_date": "2028-06",
      "has_results": false,
      "last_update_posted_date": "2026-06-08",
      "last_synced_at": "2026-06-10T06:13:56.514Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07523113"
    },
    {
      "nct_id": "NCT07285473",
      "title": "Low-Dose Naltrexone For ME/CFS: Dose-Finding",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome"
      ],
      "interventions": [
        {
          "name": "Low-Dose Naltrexone, 1.5mg",
          "type": "DRUG"
        },
        {
          "name": "Low-Dose Naltrexone, 3.0mg",
          "type": "DRUG"
        },
        {
          "name": "Low-Dose Naltrexone, 4.5mg",
          "type": "DRUG"
        },
        {
          "name": "Low-Dose Naltrexone, 6.0mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 75,
      "start_date": "2026-09-01",
      "completion_date": "2028-04-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-14",
      "last_synced_at": "2026-06-10T06:13:56.514Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07285473"
    }
  ]
}