{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=NEC",
    "query": {
      "condition": "NEC"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 93,
    "total_pages": 10,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=NEC&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T14:03:52.752Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04284280",
      "title": "Early Routine vs. Selective Human Milk Fortification in Extremely Preterm Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Poor Growth in Extremely Preterm Infants",
        "Necrotizing Enterocolitis"
      ],
      "interventions": [
        {
          "name": "Routine vs Selective use of Human Milk Donor Fortifier",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Crouse Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Days",
        "maximum_age": "6 Days",
        "sex": "ALL",
        "summary": "0 Days to 6 Days"
      },
      "enrollment_count": 170,
      "start_date": "2020-02-15",
      "completion_date": "2025-11-11",
      "has_results": false,
      "last_update_posted_date": "2026-04-30",
      "last_synced_at": "2026-07-22T14:03:52.752Z",
      "location_count": 1,
      "location_summary": "Syracuse, New York",
      "locations": [
        {
          "city": "Syracuse",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04284280"
    },
    {
      "nct_id": "NCT02400697",
      "title": "Placental Transfusion Project for Preterm Infants",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Intraventricular Hemorrhage",
        "Sepsis",
        "Necrotizing Enterocolitis"
      ],
      "interventions": [
        {
          "name": "<30 wks gestation or 1500 grams",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "12 Months",
        "sex": "ALL",
        "summary": "Up to 12 Months"
      },
      "enrollment_count": 2856,
      "start_date": "2014-09",
      "completion_date": "2016-12",
      "has_results": false,
      "last_update_posted_date": "2017-03-16",
      "last_synced_at": "2026-07-22T14:03:52.752Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02400697"
    },
    {
      "nct_id": "NCT04923126",
      "title": "SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Low-Grade Glioma",
        "Recurrent Low-Grade Glioma",
        "Progressive Low-Grade Glioma"
      ],
      "interventions": [
        {
          "name": "Mirdametinib",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "St. Jude Children's Research Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "24 Years",
        "sex": "ALL",
        "summary": "2 Years to 24 Years"
      },
      "enrollment_count": 132,
      "start_date": "2021-06-21",
      "completion_date": "2031-06",
      "has_results": false,
      "last_update_posted_date": "2026-02-04",
      "last_synced_at": "2026-07-22T14:03:52.752Z",
      "location_count": 1,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04923126"
    },
    {
      "nct_id": "NCT02698163",
      "title": "Nanodiamond Modified Gutta Percha (NDGP) Composite for Non-surgical Root Canal Therapy (RCT) Filler Material",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Pulp Diseases",
        "Dental Pulp Necrosis",
        "Nerve Root Pain Nec"
      ],
      "interventions": [
        {
          "name": "Nanodiamond reinforced Gutta Percha",
          "type": "DEVICE"
        },
        {
          "name": "Gutta Percha",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4,
      "start_date": "2016-03",
      "completion_date": "2021-03",
      "has_results": true,
      "last_update_posted_date": "2022-01-21",
      "last_synced_at": "2026-07-22T14:03:52.752Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02698163"
    },
    {
      "nct_id": "NCT01949896",
      "title": "Impact of Feeding on Pro-Inflammatory Cytokine Response in Neonates Receiving a RBC Transfusion",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Transfusions"
      ],
      "interventions": [
        {
          "name": "NPO",
          "type": "OTHER"
        },
        {
          "name": "Control group: continue feedings",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Christiana Care Health Services",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Days",
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "3 Days to 6 Months"
      },
      "enrollment_count": 12,
      "start_date": "2013-09",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2016-03-11",
      "last_synced_at": "2026-07-22T14:03:52.752Z",
      "location_count": 1,
      "location_summary": "Newark, Delaware",
      "locations": [
        {
          "city": "Newark",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01949896"
    },
    {
      "nct_id": "NCT07006727",
      "title": "Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Small Cell Lung Carcinoma",
        "Large Cell Neuroendocrine Carcinoma of the Lung",
        "Neuroendocrine Prostate Cancer",
        "Gastroenteropancreatic Neuroendocrine Carcinoma"
      ],
      "interventions": [
        {
          "name": "225Ac-ETN029",
          "type": "DRUG"
        },
        {
          "name": "111In-ETN029",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Novartis Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 116,
      "start_date": "2025-10-16",
      "completion_date": "2031-08-29",
      "has_results": false,
      "last_update_posted_date": "2026-05-05",
      "last_synced_at": "2026-07-22T14:03:52.752Z",
      "location_count": 4,
      "location_summary": "Iowa City, Iowa • Boston, Massachusetts • Royal Oak, Michigan + 1 more",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Royal Oak",
          "state": "Michigan"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07006727"
    },
    {
      "nct_id": "NCT01954017",
      "title": "STP206 for the Prevention of Necrotizing Enterocolitis (NEC)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Necrotizing Enterocolitis"
      ],
      "interventions": [
        {
          "name": "STP206",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "Leadiant Biosciences, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "4 Days",
        "sex": "ALL",
        "summary": "1 Day to 4 Days"
      },
      "enrollment_count": 103,
      "start_date": "2014-01-30",
      "completion_date": "2018-10-22",
      "has_results": true,
      "last_update_posted_date": "2020-03-24",
      "last_synced_at": "2026-07-22T14:03:52.752Z",
      "location_count": 13,
      "location_summary": "Hartford, Connecticut • Sunrise, Florida • Augusta, Georgia + 10 more",
      "locations": [
        {
          "city": "Hartford",
          "state": "Connecticut"
        },
        {
          "city": "Sunrise",
          "state": "Florida"
        },
        {
          "city": "Augusta",
          "state": "Georgia"
        },
        {
          "city": "Evanston",
          "state": "Illinois"
        },
        {
          "city": "Springfield",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01954017"
    },
    {
      "nct_id": "NCT03142685",
      "title": "Utility of Bowel Ultrasound in Diagnosing Necrotizing Eneterocolitis in Congenital Heart Disease",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Enterocolitis, Necrotizing",
        "Congenital Heart Disease"
      ],
      "interventions": [
        {
          "name": "Bowel Ultrasound",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Mercy Hospital Kansas City",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "Up to 6 Months"
      },
      "enrollment_count": 0,
      "start_date": "2017-01-01",
      "completion_date": "2018-06-30",
      "has_results": false,
      "last_update_posted_date": "2018-07-18",
      "last_synced_at": "2026-07-22T14:03:52.752Z",
      "location_count": 1,
      "location_summary": "Kansas City, Missouri",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03142685"
    },
    {
      "nct_id": "NCT06547424",
      "title": "Phase I Clinical Study of Chondroitin Sulfate for Treatment of NEC",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Necrotizing Enterocolitis",
        "Intestinal Ischemia"
      ],
      "interventions": [
        {
          "name": "Chondroitin sulfate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Hour",
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "1 Hour to 6 Months"
      },
      "enrollment_count": 0,
      "start_date": "2025-01",
      "completion_date": "2029-03",
      "has_results": false,
      "last_update_posted_date": "2025-10-10",
      "last_synced_at": "2026-07-22T14:03:52.752Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06547424"
    },
    {
      "nct_id": "NCT03376984",
      "title": "Nanodiamond-Gutta Percha Composite Biomaterials for Root Canal Therapy",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Dental Pulp Diseases",
        "Dental Pulp Necrosis",
        "Nerve Root Pain Nec"
      ],
      "interventions": [
        {
          "name": "ND and AMOX modified Gutta Percha",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Gutta Percha",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT",
        "DEVICE"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2023-06",
      "completion_date": "2025-06",
      "has_results": false,
      "last_update_posted_date": "2023-09-21",
      "last_synced_at": "2026-07-22T14:03:52.752Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03376984"
    }
  ]
}