{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=NGS&page=2", "query": { "condition": "NGS", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=NGS&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-05T08:09:16.522Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05275673", "title": "A Study of Sapanisertib in Relapsed/Refractory NFE2L2-Mutated and Wild-Type Squamous Non-Small Cell Lung Cancer", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Non-Small Cell Lung Cancer", "Squamous Non-small-cell Lung Cancer", "Squamous Non-Small Cell Neoplasm of Lung", "NFE2L2 Gene Mutation" ], "interventions": [ { "name": "sapanisertib", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Faeth Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 7, "start_date": "2022-07-21", "completion_date": "2023-01-24", "has_results": true, "last_update_posted_date": "2025-04-24", "last_synced_at": "2026-09-05T08:09:16.522Z", "location_count": 14, "location_summary": "Davis, California • Santa Rosa, California • Fort Myers, Florida + 11 more", "locations": [ { "city": "Davis", "state": "California" }, { "city": "Santa Rosa", "state": "California" }, { "city": "Fort Myers", "state": "Florida" }, { "city": "Ocala", "state": "Florida" }, { "city": "Tallahassee", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05275673" }, { "nct_id": "NCT07006831", "title": "A Multicenter, Prospective Blood Collection Study in a Kidney Transplant Population", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Kidney Disease", "Kidney Transplant", "Transplant Recipient", "Renal Function", "Cell-free DNA", "NGS" ], "interventions": [], "intervention_types": [], "sponsor": "Devyser Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 400, "start_date": "2025-11-14", "completion_date": "2028-03", "has_results": false, "last_update_posted_date": "2026-08-21", "last_synced_at": "2026-09-05T08:09:16.522Z", "location_count": 6, "location_summary": "San Diego, California • San Francisco, California • Atlanta, Georgia + 3 more", "locations": [ { "city": "San Diego", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT07006831" }, { "nct_id": "NCT02988414", "title": "Diagnosis of Bacteremia/Septicemia and Culture Negative Endocarditis by the Karius Sequencing-Based Infectious Disease Diagnostic Assay", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Bacteremia", "Septicemia" ], "interventions": [], "intervention_types": [], "sponsor": "Karius, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 108, "start_date": "2016-07", "completion_date": "2017-04", "has_results": false, "last_update_posted_date": "2018-05-11", "last_synced_at": "2026-09-05T08:09:16.522Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT02988414" }, { "nct_id": "NCT04047719", "title": "Pneumonia in the ImmunoCompromised - Use of the Karius Test for the Detection of Undiagnosed Pathogens", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Pneumonia, Bacterial", "Pneumonia, Viral", "Pneumonia Fungal", "Pneumonia Cavitary", "Immunocompromised Host" ], "interventions": [ { "name": "Karius Test", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Karius, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 257, "start_date": "2019-11-05", "completion_date": "2022-06-06", "has_results": false, "last_update_posted_date": "2023-02-09", "last_synced_at": "2026-09-05T08:09:16.522Z", "location_count": 10, "location_summary": "Duarte, California • San Francisco, California • Aurora, Colorado + 6 more", "locations": [ { "city": "Duarte", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "New Orleans", "state": "Louisiana" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT04047719" }, { "nct_id": "NCT03521245", "title": "Molecular Pathway Activation Markers Predicting Efficacy of Trastuzumab Therapy for HER2-positive Breast Cancer", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "HER2-positive Breast Cancer" ], "interventions": [ { "name": "RNA sequencing", "type": "OTHER" }, { "name": "Transcriptome analysis", "type": "OTHER" }, { "name": "Trastuzumab", "type": "DRUG" }, { "name": "Chemotherapy", "type": "DRUG" } ], "intervention_types": [ "OTHER", "DRUG" ], "sponsor": "OmicsWay Corp.", "sponsor_class": "INDUSTRY", "healthy_volunteers": null, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "FEMALE", "summary": "18 Years to 80 Years · Female only" }, "enrollment_count": 40, "start_date": "2017-10-01", "completion_date": "2022-05-01", "has_results": false, "last_update_posted_date": "2021-09-14", "last_synced_at": "2026-09-05T08:09:16.522Z", "location_count": 1, "location_summary": "Walnut, California", "locations": [ { "city": "Walnut", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03521245" }, { "nct_id": "NCT04698681", "title": "NGS Screening Protocol to Detect Mutation of KEAP1 or NRF2/NFE2L2 Genes for the KEAPSAKE (CX-839-014) Trial", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Non-Small Cell Lung Cancer", "Non-squamous Non-small-cell Lung Cancer", "Non-Squamous Non-Small Cell Neoplasm of Lung", "KEAP1 Gene Mutation", "NRF2 Mutation", "NFE2L2 Gene Mutation" ], "interventions": [], "intervention_types": [], "sponsor": "Calithera Biosciences, Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 20, "start_date": "2021-01-19", "completion_date": "2022-02-09", "has_results": false, "last_update_posted_date": "2023-03-13", "last_synced_at": "2026-09-05T08:09:16.522Z", "location_count": 63, "location_summary": "Daphne, Alabama • Mobile, Alabama • Glendale, Arizona + 52 more", "locations": [ { "city": "Daphne", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Glendale", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT04698681" }, { "nct_id": "NCT06163534", "title": "A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Head and Neck Squamous Cell Carcinoma" ], "interventions": [], "intervention_types": [], "sponsor": "Tempus AI", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 500, "start_date": "2024-08-01", "completion_date": "2028-03-01", "has_results": false, "last_update_posted_date": "2026-09-03", "last_synced_at": "2026-09-05T08:09:16.522Z", "location_count": 31, "location_summary": "Duarte, California • Los Angeles, California • Palo Alto, California + 25 more", "locations": [ { "city": "Duarte", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "Santa Rosa", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06163534" }, { "nct_id": "NCT05247281", "title": "NGS vs Culture Outcomes for Treatment of PJI", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Prosthetic Joint Infection" ], "interventions": [ { "name": "Culture-based treatment", "type": "DIAGNOSTIC_TEST" }, { "name": "Next Generation Sequencing (NGS) with Culture", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Center for Innovation and Research Organization", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 250, "start_date": "2022-09-21", "completion_date": "2025-05", "has_results": false, "last_update_posted_date": "2023-11-08", "last_synced_at": "2026-09-05T08:09:16.522Z", "location_count": 9, "location_summary": "Los Angeles, California • Weston, Florida • Lebanon, New Hampshire + 6 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Weston", "state": "Florida" }, { "city": "Lebanon", "state": "New Hampshire" }, { "city": "New York", "state": "New York" }, { "city": "Rochester", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT05247281" }, { "nct_id": "NCT07392970", "title": "Motixafortide for MRD Sensitization in AML", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Acute Myeloid Leukemia", "Measurable Residual Disease" ], "interventions": [ { "name": "Motixafortide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 10, "start_date": "2026-07-23", "completion_date": "2030-02-02", "has_results": false, "last_update_posted_date": "2026-07-24", "last_synced_at": "2026-09-05T08:09:16.522Z", "location_count": 1, "location_summary": "St Louis, Missouri", "locations": [ { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT07392970" }, { "nct_id": "NCT05199584", "title": "A Study Evaluating the Safety and Efficacy of ENV-101 (Taladegib) in Patients With Advanced Solid Tumors Harboring PTCH1 Loss of Function Mutations", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Solid Tumors With PTCH1 Loss-of-function Mutations" ], "interventions": [ { "name": "ENV-101 (taladegib)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Endeavor Biomedicines, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 20, "start_date": "2022-05-24", "completion_date": "2024-02-20", "has_results": false, "last_update_posted_date": "2026-03-05", "last_synced_at": "2026-09-05T08:09:16.522Z", "location_count": 16, "location_summary": "Los Angeles, California • Santa Rosa, California • Tampa, Florida + 13 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Santa Rosa", "state": "California" }, { "city": "Tampa", "state": "Florida" }, { "city": "Zion", "state": "Illinois" }, { "city": "Covington", "state": "Louisiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT05199584" } ] }