{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=NRAS+G13D",
    "query": {
      "condition": "NRAS G13D"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 5,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:38:52.799Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05786924",
      "title": "Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Non-small Cell Lung Cancer",
        "Histiocytic Neoplasm",
        "Histiocytosis",
        "BRAF Gene Mutation",
        "BRAF V600E",
        "BRAF V600 Mutation",
        "BRAF Mutation-Related Tumors",
        "BRAF",
        "Metastatic Lung Non-Small Cell Carcinoma",
        "Metastatic Lung Cancer",
        "Recurrent Lung Cancer",
        "Recurrent Lung Non-Small Cell Carcinoma",
        "NSCLC",
        "Solid Tumor",
        "Solid Carcinoma",
        "KRAS G12D",
        "KRAS G12V",
        "KRAS Mutation-Related Tumors",
        "NRAS Gene Mutation",
        "Thyroid Cancer",
        "Thyroid Carcinoma",
        "Colorectal Cancer",
        "Colorectal Carcinoma",
        "Recurrent Histiocytic and Dendritic Cell Neoplasm",
        "Brain Metastases",
        "Recurrent NSCLC",
        "KRAS G13C",
        "Acquired Resistance to KRAS G12C Inhibitor",
        "KRAS G12A",
        "KRAS G12F",
        "KRAS G12R",
        "KRAS G13D"
      ],
      "interventions": [
        {
          "name": "S241656",
          "type": "DRUG"
        },
        {
          "name": "FOLFOX6/FOLFOX7",
          "type": "DRUG"
        },
        {
          "name": "FOLFIRI",
          "type": "DRUG"
        },
        {
          "name": "Cetuximab",
          "type": "DRUG"
        },
        {
          "name": "Panitumumab",
          "type": "DRUG"
        },
        {
          "name": "Gemcitabine",
          "type": "DRUG"
        },
        {
          "name": "Nab-paclitaxel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Institut de Recherches Internationales Servier",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 554,
      "start_date": "2023-04-18",
      "completion_date": "2028-06",
      "has_results": false,
      "last_update_posted_date": "2026-04-21",
      "last_synced_at": "2026-05-22T05:38:52.799Z",
      "location_count": 10,
      "location_summary": "Gilbert, Arizona • Aurora, Colorado • Washington D.C., District of Columbia + 7 more",
      "locations": [
        {
          "city": "Gilbert",
          "state": "Arizona"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Grand Rapids",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05786924"
    },
    {
      "nct_id": "NCT07252479",
      "title": "Evaluation of RAS Inhibitor Treatment in Participants With Advanced or Metastatic Solid Tumors Harboring RAS Mutations",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Solid Tumors (Phase 1)",
        "RAS Mutation"
      ],
      "interventions": [
        {
          "name": "AN9025 oral capsule",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Adlai Nortye Biopharma Co., Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 91,
      "start_date": "2026-01-28",
      "completion_date": "2028-06-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-11",
      "last_synced_at": "2026-05-22T05:38:52.799Z",
      "location_count": 2,
      "location_summary": "Orlando, Florida • Houston, Texas",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07252479"
    },
    {
      "nct_id": "NCT05585320",
      "title": "A Phase 1/2a Study of IMM-1-104 in Participants With Advanced or Metastatic Solid Tumors",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Advanced Solid Tumor",
        "Pancreatic Adenocarcinoma",
        "Malignant Melanoma (Cutaneous)",
        "Non-small Cell Lung Cancer (NSCLC)"
      ],
      "interventions": [
        {
          "name": "IMM-1-104 Monotherapy (Treatment Group A)",
          "type": "DRUG"
        },
        {
          "name": "IMM-1-104 + modified Gemcitabine/nab-Paclitaxel (Treatment Group B)",
          "type": "DRUG"
        },
        {
          "name": "IMM-1-104 + modified FOLFIRINOX (Treatment Group C)",
          "type": "DRUG"
        },
        {
          "name": "IMM-1-104 + dabrafenib (Treatment Group D)",
          "type": "DRUG"
        },
        {
          "name": "IMM-1-104 + pembrolizumab (Treatment Group E)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Immuneering Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 209,
      "start_date": "2022-10-31",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2025-09-02",
      "last_synced_at": "2026-05-22T05:38:52.799Z",
      "location_count": 20,
      "location_summary": "Scottsdale, Arizona • Duarte, California • San Diego, California + 16 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Duarte",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05585320"
    },
    {
      "nct_id": "NCT07584226",
      "title": "A First-in-human Study of RLY-8161 in Advanced NRAS-Mutant Solid Tumors",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "NRAS Mutation",
        "NRAS-mutant Advanced Melanoma",
        "NRAS-mutant Solid Tumors",
        "NRAS Q61R",
        "NRAS Q61K",
        "NRAS Q61L",
        "NRAS Q61H",
        "NRAS G12D",
        "NRAS G13R",
        "NRAS G13D",
        "NRAS G12V"
      ],
      "interventions": [
        {
          "name": "RLY-8161",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Relay Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 35,
      "start_date": "2026-03-09",
      "completion_date": "2029-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-13",
      "last_synced_at": "2026-05-22T05:38:52.799Z",
      "location_count": 4,
      "location_summary": "Boston, Massachusetts • Grand Rapids, Michigan • New York, New York + 1 more",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Grand Rapids",
          "state": "Michigan"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Fairfax",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07584226"
    },
    {
      "nct_id": "NCT05726864",
      "title": "A Study of ELI-002 7P in Subjects With KRAS/NRAS Mutated Solid Tumors",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Pancreatic Ductal Adenocarcinoma",
        "Colorectal Cancer",
        "KRAS G12D",
        "KRAS G12R",
        "KRAS G12V",
        "KRAS G12A",
        "KRAS G12C",
        "KRAS G12S",
        "KRAS G13D",
        "NRAS G12D",
        "NRAS G12R",
        "NRAS G12V",
        "NRAS G12C",
        "NRAS G12S"
      ],
      "interventions": [
        {
          "name": "ELI-002 7P",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Elicio Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 158,
      "start_date": "2023-04-14",
      "completion_date": "2026-11",
      "has_results": false,
      "last_update_posted_date": "2026-05-19",
      "last_synced_at": "2026-05-22T05:38:52.799Z",
      "location_count": 28,
      "location_summary": "Gilbert, Arizona • Phoenix, Arizona • Duarte, California + 21 more",
      "locations": [
        {
          "city": "Gilbert",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Duarte",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05726864"
    }
  ]
}