{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Nasolacrimal+Duct+Obstruction",
    "query": {
      "condition": "Nasolacrimal Duct Obstruction"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T10:43:28.057Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05663684",
      "title": "Does Topical Ophthalmic Proparacaine 0.5% Prior to Probing and Irrigation Decrease Pain?",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Epiphora",
        "Dacryostenosis",
        "Dacryocystitis"
      ],
      "interventions": [
        {
          "name": "Proparacaine Hydrochloride ophthalmic solution, USP 0.5%",
          "type": "DRUG"
        },
        {
          "name": "Balanced salt solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Louisiana State University Health Sciences Center in New Orleans",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 145,
      "start_date": "2020-06-30",
      "completion_date": "2023-01-31",
      "has_results": false,
      "last_update_posted_date": "2022-12-23",
      "last_synced_at": "2026-06-10T10:43:28.057Z",
      "location_count": 1,
      "location_summary": "New Orleans, Louisiana",
      "locations": [
        {
          "city": "New Orleans",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05663684"
    },
    {
      "nct_id": "NCT03705000",
      "title": "SLlt Stent II Lacrimal Stent for the Treatment of Nasolacrimal Duct Obstruction",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Epiphora",
        "Dacryocystorhinostomy"
      ],
      "interventions": [
        {
          "name": "Slit Stent II",
          "type": "DEVICE"
        },
        {
          "name": "BIKA for DCR",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Thomas Gardner",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2020-10-16",
      "completion_date": "2022-05-11",
      "has_results": true,
      "last_update_posted_date": "2026-02-25",
      "last_synced_at": "2026-06-10T10:43:28.057Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03705000"
    },
    {
      "nct_id": "NCT01766232",
      "title": "Lacrimal Drainage Resistance Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Epiphora",
        "Nasolacrimal Duct Obstruction",
        "Canalicular Stenosis",
        "Functional Tear Pump Failure",
        "Ectropion"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2009-04",
      "completion_date": "2015-02",
      "has_results": false,
      "last_update_posted_date": "2015-02-19",
      "last_synced_at": "2026-06-10T10:43:28.057Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01766232"
    },
    {
      "nct_id": "NCT00315315",
      "title": "Study of Surgical Procedures for Treatment of Persistent Nasolacrimal Duct Obstruction in Children < 4 Years Old",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Nasolacrimal Duct Obstruction"
      ],
      "interventions": [
        {
          "name": "Nasolacrimal balloon catheter dilation",
          "type": "PROCEDURE"
        },
        {
          "name": "Nasolacrimal intubation",
          "type": "PROCEDURE"
        },
        {
          "name": "Nasolacrimal duct probing",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Jaeb Center for Health Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "47 Months",
        "sex": "ALL",
        "summary": "6 Months to 47 Months"
      },
      "enrollment_count": 194,
      "start_date": "2005-02",
      "completion_date": "2008-02",
      "has_results": false,
      "last_update_posted_date": "2012-05-17",
      "last_synced_at": "2026-06-10T10:43:28.057Z",
      "location_count": 2,
      "location_summary": "Baltimore, Maryland • Lancaster, Pennsylvania",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Lancaster",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00315315"
    },
    {
      "nct_id": "NCT05999630",
      "title": "Artificial Tears to Prevent Nasolacrimal Duct Obstruction in Patients Treated With Radioactive Iodine for Thyroid Cancer",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Nasolacrimal Duct Obstruction",
        "Thyroid Cancer"
      ],
      "interventions": [
        {
          "name": "Artificial Tears Methylcellulose",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2023-08-21",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-10-28",
      "last_synced_at": "2026-06-10T10:43:28.057Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05999630"
    },
    {
      "nct_id": "NCT00780741",
      "title": "Immediate Office Probing vs Deferred Facility Probing for Nasolacrimal Duct Obstruction in Children 6 to <10 Months Old",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Nasolacrimal Duct Obstruction"
      ],
      "interventions": [
        {
          "name": "Immediate Office Probing",
          "type": "PROCEDURE"
        },
        {
          "name": "Deferred Facility Probing",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Jaeb Center for Health Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "10 Months",
        "sex": "ALL",
        "summary": "6 Months to 10 Months"
      },
      "enrollment_count": 220,
      "start_date": "2008-10",
      "completion_date": "2012-01",
      "has_results": true,
      "last_update_posted_date": "2016-06-24",
      "last_synced_at": "2026-06-10T10:43:28.057Z",
      "location_count": 1,
      "location_summary": "Boise, Idaho",
      "locations": [
        {
          "city": "Boise",
          "state": "Idaho"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00780741"
    },
    {
      "nct_id": "NCT00315289",
      "title": "Study of Primary Surgical Treatment of Nasolacrimal Duct Obstruction in Children Less Than Four Years Old",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Nasolacrimal Duct Obstruction"
      ],
      "interventions": [
        {
          "name": "Nasolacrimal balloon catheter duct dilation",
          "type": "PROCEDURE"
        },
        {
          "name": "Nasolacrimal intubation",
          "type": "PROCEDURE"
        },
        {
          "name": "Simple Nasolacrimal duct probing",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Jaeb Center for Health Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "47 Months",
        "sex": "ALL",
        "summary": "6 Months to 47 Months"
      },
      "enrollment_count": 973,
      "start_date": "2005-02",
      "completion_date": "2006-09",
      "has_results": false,
      "last_update_posted_date": "2010-03-02",
      "last_synced_at": "2026-06-10T10:43:28.057Z",
      "location_count": 2,
      "location_summary": "Baltimore, Maryland • Lancaster, Pennsylvania",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Lancaster",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00315289"
    },
    {
      "nct_id": "NCT07289854",
      "title": "Portable Endoscopic Camera System Using Modified Action Camera for Endoscopic Sinunasal Examination",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Nasolacrimal Duct Obstruction",
        "Nasolacrimal Tract Obstruction"
      ],
      "interventions": [
        {
          "name": "Modified Portable Endoscopic Camera",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Arkansas",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2025-12-16",
      "completion_date": "2026-11",
      "has_results": false,
      "last_update_posted_date": "2026-01-08",
      "last_synced_at": "2026-06-10T10:43:28.057Z",
      "location_count": 1,
      "location_summary": "Little Rock, Arkansas",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07289854"
    },
    {
      "nct_id": "NCT01431170",
      "title": "Safety and Efficacy Study of Besivance™ for Treatment of Congenital Nasolacrimal Duct Obstruction in Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Congenital Nasolacrimal Duct Obstruction"
      ],
      "interventions": [
        {
          "name": "Besivance Treatment Group",
          "type": "DRUG"
        },
        {
          "name": "Polytrim Treatment Group",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": "12 Months",
        "sex": "ALL",
        "summary": "1 Month to 12 Months"
      },
      "enrollment_count": 24,
      "start_date": "2011-09",
      "completion_date": "2014-06",
      "has_results": true,
      "last_update_posted_date": "2016-07-14",
      "last_synced_at": "2026-06-10T10:43:28.057Z",
      "location_count": 1,
      "location_summary": "Newark, New Jersey",
      "locations": [
        {
          "city": "Newark",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01431170"
    },
    {
      "nct_id": "NCT04229771",
      "title": "Does Topical Ophthalmic Anesthetic Prior to Probing and Irrigation Decrease Pain?",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Epiphora",
        "Dacryostenosis",
        "Dacryocystitis"
      ],
      "interventions": [
        {
          "name": "Proparacaine Hydrochloride ophthalmic solution, USP 0.5%",
          "type": "DRUG"
        },
        {
          "name": "Balanced salt solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Corewell Health East",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2020-06-30",
      "completion_date": "2020-11-30",
      "has_results": true,
      "last_update_posted_date": "2023-01-19",
      "last_synced_at": "2026-06-10T10:43:28.057Z",
      "location_count": 1,
      "location_summary": "Royal Oak, Michigan",
      "locations": [
        {
          "city": "Royal Oak",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04229771"
    }
  ]
}