{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Necrosis&page=2",
    "query": {
      "condition": "Necrosis",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Necrosis&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:43:36.615Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00646906",
      "title": "Mechanisms of Action of Acetaminophen",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myocardial Infarction",
        "Arthritis"
      ],
      "interventions": [
        {
          "name": "Aspirin First",
          "type": "DRUG"
        },
        {
          "name": "Aspirin Last",
          "type": "DRUG"
        },
        {
          "name": "Acetaminophen 1000 mg/d",
          "type": "DRUG"
        },
        {
          "name": "Acetaminophen 4000 mg/d",
          "type": "DRUG"
        },
        {
          "name": "Ibuprofen 800 mg/d",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 55,
      "start_date": "2004-06-02",
      "completion_date": "2012-01-24",
      "has_results": true,
      "last_update_posted_date": "2026-02-12",
      "last_synced_at": "2026-05-22T05:43:36.615Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00646906"
    },
    {
      "nct_id": "NCT05138289",
      "title": "The REVEALPLAQUE Study: A pRospEctiVe, multicEnter Study to AnaLyze PLAQUE Using CCTA",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD))"
      ],
      "interventions": [
        {
          "name": "Total Plaque Volume",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "HeartFlow, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 258,
      "start_date": "2021-10-12",
      "completion_date": "2022-11-08",
      "has_results": true,
      "last_update_posted_date": "2025-08-22",
      "last_synced_at": "2026-05-22T05:43:36.615Z",
      "location_count": 1,
      "location_summary": "Lincoln, Nebraska",
      "locations": [
        {
          "city": "Lincoln",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05138289"
    },
    {
      "nct_id": "NCT01763684",
      "title": "Oxford Signature vs. Conventional Global Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis",
        "Osteoarthritis, Knee",
        "Osteonecrosis"
      ],
      "interventions": [
        {
          "name": "Signature Custom Guides",
          "type": "DEVICE"
        },
        {
          "name": "Conventional Instrumentation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 266,
      "start_date": "2012-09",
      "completion_date": "2016-08",
      "has_results": true,
      "last_update_posted_date": "2021-04-23",
      "last_synced_at": "2026-05-22T05:43:36.615Z",
      "location_count": 7,
      "location_summary": "Elkhart, Indiana • Rockville, Maryland • Columbia, Missouri + 4 more",
      "locations": [
        {
          "city": "Elkhart",
          "state": "Indiana"
        },
        {
          "city": "Rockville",
          "state": "Maryland"
        },
        {
          "city": "Columbia",
          "state": "Missouri"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01763684"
    },
    {
      "nct_id": "NCT00682526",
      "title": "Pre-Hospital Wireless Transmission of Electrocardiograms to a Cardiologist Via a Hand-Held Device",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Myocardial Infarction"
      ],
      "interventions": [
        {
          "name": "SmartLink Wireless Monitoring System (K033642)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Welch Allyn",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 527,
      "start_date": "2003-06",
      "completion_date": "2010-05",
      "has_results": false,
      "last_update_posted_date": "2012-02-23",
      "last_synced_at": "2026-05-22T05:43:36.615Z",
      "location_count": 7,
      "location_summary": "Salinas, California • Gainesville, Florida • Miami, Florida + 3 more",
      "locations": [
        {
          "city": "Salinas",
          "state": "California"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00682526"
    },
    {
      "nct_id": "NCT02054533",
      "title": "Study to Determine Risk Factors for Post-operative Infection in Inflammatory Bowel Disease",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Crohn's Disease",
        "Ulcerative Colitis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 974,
      "start_date": "2014-02",
      "completion_date": "2017-06-30",
      "has_results": false,
      "last_update_posted_date": "2017-09-13",
      "last_synced_at": "2026-05-22T05:43:36.615Z",
      "location_count": 24,
      "location_summary": "Scottsdale, Arizona • Los Angeles, California • San Francisco, California + 17 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02054533"
    },
    {
      "nct_id": "NCT00800163",
      "title": "Improving Door-to-Balloon Time in STEMI",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myocardial Infarction"
      ],
      "interventions": [
        {
          "name": "ED Activation/Immediate Transfer",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "St. Francis Hospitals & Health Centers",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1000,
      "start_date": "2005-09",
      "completion_date": "2012-09",
      "has_results": false,
      "last_update_posted_date": "2010-07-23",
      "last_synced_at": "2026-05-22T05:43:36.615Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00800163"
    },
    {
      "nct_id": "NCT00046228",
      "title": "A Study of Abciximab and Reteplase When Administered Prior to Catherization After a Myocardial Infarction (Finesse)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Myocardial Infarction"
      ],
      "interventions": [
        {
          "name": "abciximab placebo; reteplase placebo, abciximab, abciximab",
          "type": "DRUG"
        },
        {
          "name": "Abciximab; reteplase; abciximab placebo; abciximab",
          "type": "DRUG"
        },
        {
          "name": "abciximab; reteplase placebo; abciximab placebo; abciximab",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Centocor, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 2461,
      "start_date": "2002-08",
      "completion_date": "2008-01",
      "has_results": true,
      "last_update_posted_date": "2014-07-31",
      "last_synced_at": "2026-05-22T05:43:36.615Z",
      "location_count": 52,
      "location_summary": "Phoenix, Arizona • Covina, California • Modesto, California + 49 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Covina",
          "state": "California"
        },
        {
          "city": "Modesto",
          "state": "California"
        },
        {
          "city": "Newark",
          "state": "Delaware"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00046228"
    },
    {
      "nct_id": "NCT06095557",
      "title": "MCG Discovery Study in Emergency Departments",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACS - Acute Coronary Syndrome",
        "NSTEMI - Non-ST Segment Elevation MI"
      ],
      "interventions": [
        {
          "name": "Sponsor MCG device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "SB Technology, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 124,
      "start_date": "2023-10-30",
      "completion_date": "2025-07-08",
      "has_results": false,
      "last_update_posted_date": "2025-10-21",
      "last_synced_at": "2026-05-22T05:43:36.615Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06095557"
    },
    {
      "nct_id": "NCT00912041",
      "title": "BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tetraplegia",
        "Spinal Cord Injuries",
        "Amyotrophic Lateral Sclerosis",
        "Brain Stem Infarctions",
        "Locked in Syndrome",
        "Muscular Dystrophy"
      ],
      "interventions": [
        {
          "name": "Placement of the BrainGate2 sensor(s) into the motor-related cortex",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Leigh R. Hochberg, MD, PhD.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 27,
      "start_date": "2009-05",
      "completion_date": "2038-12",
      "has_results": false,
      "last_update_posted_date": "2025-12-03",
      "last_synced_at": "2026-05-22T05:43:36.615Z",
      "location_count": 5,
      "location_summary": "Sacramento, California • Stanford, California • Atlanta, Georgia + 2 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00912041"
    },
    {
      "nct_id": "NCT06569329",
      "title": "Bacterial Reduction After Supplementary Disinfection Procedures in Infected Root Canals",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Pulp Necroses"
      ],
      "interventions": [
        {
          "name": "GentleWave System Root Canal Therapy",
          "type": "DEVICE"
        },
        {
          "name": "EdgePro Laser Root Canal Therapy",
          "type": "DEVICE"
        },
        {
          "name": "The ProUltra Piezo Ultrasonic with EndoUltra Tips Root Canal Therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abhishek Parolia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "18 Years to 95 Years"
      },
      "enrollment_count": 90,
      "start_date": "2024-08-20",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2025-09-17",
      "last_synced_at": "2026-05-22T05:43:36.615Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06569329"
    }
  ]
}