{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Necrotising+Enterocolitis+Neonatal&page=2",
    "query": {
      "condition": "Necrotising Enterocolitis Neonatal",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Necrotising+Enterocolitis+Neonatal&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T03:56:12.564Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00009646",
      "title": "Trial of Indomethacin Prophylaxis in Preterm Infants (TIPP)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Infant, Very Low Birth Weight",
        "Infant, Premature",
        "Ductus Arteriosus, Patent"
      ],
      "interventions": [
        {
          "name": "Indomethacin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Hours",
        "maximum_age": "6 Hours",
        "sex": "ALL",
        "summary": "2 Hours to 6 Hours"
      },
      "enrollment_count": 1202,
      "start_date": "1993-11",
      "completion_date": "2001-03",
      "has_results": false,
      "last_update_posted_date": "2015-06-08",
      "last_synced_at": "2026-06-10T03:56:12.564Z",
      "location_count": 9,
      "location_summary": "Birmingham, Alabama • Palo Alto, California • Miami, Florida + 6 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00009646"
    },
    {
      "nct_id": "NCT01949896",
      "title": "Impact of Feeding on Pro-Inflammatory Cytokine Response in Neonates Receiving a RBC Transfusion",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Transfusions"
      ],
      "interventions": [
        {
          "name": "NPO",
          "type": "OTHER"
        },
        {
          "name": "Control group: continue feedings",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Christiana Care Health Services",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Days",
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "3 Days to 6 Months"
      },
      "enrollment_count": 12,
      "start_date": "2013-09",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2016-03-11",
      "last_synced_at": "2026-06-10T03:56:12.564Z",
      "location_count": 1,
      "location_summary": "Newark, Delaware",
      "locations": [
        {
          "city": "Newark",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01949896"
    },
    {
      "nct_id": "NCT01029353",
      "title": "Laparotomy vs. Drainage for Infants With Necrotizing Enterocolitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infant, Newborn",
        "Infant, Low Birth Weight",
        "Infant, Small for Gestational Age",
        "Infant, Premature",
        "Enterocolitis, Necrotizing",
        "Intestinal Perforation"
      ],
      "interventions": [
        {
          "name": "Laparotomy",
          "type": "PROCEDURE"
        },
        {
          "name": "Drainage",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "8 Weeks",
        "sex": "ALL",
        "summary": "Up to 8 Weeks"
      },
      "enrollment_count": 529,
      "start_date": "2010-01",
      "completion_date": "2019-08",
      "has_results": true,
      "last_update_posted_date": "2024-07-18",
      "last_synced_at": "2026-06-10T03:56:12.564Z",
      "location_count": 22,
      "location_summary": "Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 18 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01029353"
    },
    {
      "nct_id": "NCT00392977",
      "title": "Brain Manganese Deposition in High Risk Neonates",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Necrotizing Enterocolitis",
        "Digestive System Abnormalities",
        "Cholestasis"
      ],
      "interventions": [
        {
          "name": "remove Mn from PN if evidence of increased brain Mn on MRI",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Days",
        "maximum_age": "12 Months",
        "sex": "ALL",
        "summary": "30 Days to 12 Months"
      },
      "enrollment_count": 43,
      "start_date": "2006-08",
      "completion_date": "2010-12",
      "has_results": false,
      "last_update_posted_date": "2013-12-19",
      "last_synced_at": "2026-06-10T03:56:12.564Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00392977"
    },
    {
      "nct_id": "NCT00828451",
      "title": "Collaborative Research Group for Necrotizing Enterocolitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prematurity",
        "Necrotizing Enterocolitis"
      ],
      "interventions": [
        {
          "name": "[5,5,5-2H3]leucine (stable isotope labeled leucine)",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "7 Days",
        "sex": "ALL",
        "summary": "1 Day to 7 Days"
      },
      "enrollment_count": 29,
      "start_date": "2008-05",
      "completion_date": "2010-12",
      "has_results": true,
      "last_update_posted_date": "2018-04-04",
      "last_synced_at": "2026-06-10T03:56:12.564Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00828451"
    },
    {
      "nct_id": "NCT06681129",
      "title": "Study of Normal Intestinal Development and Disease in Premature and Term Neonates",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "NEC",
        "Necrotizing Enterocolitis",
        "Intestinal Disease",
        "Human Development"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "2 Years",
        "sex": "ALL",
        "summary": "Up to 2 Years"
      },
      "enrollment_count": 100,
      "start_date": "2025-03-17",
      "completion_date": "2034-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-27",
      "last_synced_at": "2026-06-10T03:56:12.564Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06681129"
    },
    {
      "nct_id": "NCT03717584",
      "title": "A Cohort Study of the Intestinal Microbiota of Premature Infants",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Necrotizing Enterocolitis",
        "Bronchopulmonary Dysplasia",
        "Growth Failure"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "33 Weeks",
        "sex": "ALL",
        "summary": "Up to 33 Weeks"
      },
      "enrollment_count": 300,
      "start_date": "2018-12-23",
      "completion_date": "2027-03-05",
      "has_results": false,
      "last_update_posted_date": "2026-04-03",
      "last_synced_at": "2026-06-10T03:56:12.564Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03717584"
    },
    {
      "nct_id": "NCT02477423",
      "title": "A Randomized Controlled Trial Investigating if Antibiotic Use in the First 48 Hours of Life Adversely Impacts the Preterm Infant Microbiome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premature Birth of Newborn",
        "Enterocolitis, Necrotizing"
      ],
      "interventions": [
        {
          "name": "Ampicillin",
          "type": "DRUG"
        },
        {
          "name": "Gentamicins",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "6 Hours",
        "sex": "ALL",
        "summary": "Up to 6 Hours"
      },
      "enrollment_count": 27,
      "start_date": "2015-07",
      "completion_date": "2019-06",
      "has_results": true,
      "last_update_posted_date": "2020-10-08",
      "last_synced_at": "2026-06-10T03:56:12.564Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02477423"
    },
    {
      "nct_id": "NCT02784821",
      "title": "Antibiotic \"Dysbiosis\" in Preterm Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Enterocolitis, Necrotizing",
        "Bacteremia",
        "Bronchopulmonary Dysplasia",
        "Intraventricular Hemorrhage",
        "Periventricular Leukomalacia",
        "Chronic Lung Disease",
        "Ileal Perforation"
      ],
      "interventions": [
        {
          "name": "Antibiotic",
          "type": "DRUG"
        },
        {
          "name": "Gastric fluid",
          "type": "OTHER"
        },
        {
          "name": "Breast milk",
          "type": "OTHER"
        },
        {
          "name": "Stool samples",
          "type": "OTHER"
        },
        {
          "name": "Antibiotics",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "23 Weeks",
        "maximum_age": "33 Weeks",
        "sex": "ALL",
        "summary": "23 Weeks to 33 Weeks"
      },
      "enrollment_count": 98,
      "start_date": "2017-01-16",
      "completion_date": "2019-09-11",
      "has_results": true,
      "last_update_posted_date": "2024-06-05",
      "last_synced_at": "2026-06-10T03:56:12.564Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02784821"
    },
    {
      "nct_id": "NCT01729000",
      "title": "Study to Determine if Gloving in Addition to Hand Hygiene Will Prevent Invasive Infections and Necrotizing Enterocolitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neonatal Infection",
        "Neonatal Necrotizing Enterocolitis"
      ],
      "interventions": [
        {
          "name": "Gloves",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "8 Days",
        "sex": "ALL",
        "summary": "Up to 8 Days"
      },
      "enrollment_count": 124,
      "start_date": "2008-10",
      "completion_date": "2011-06",
      "has_results": false,
      "last_update_posted_date": "2012-11-20",
      "last_synced_at": "2026-06-10T03:56:12.564Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01729000"
    }
  ]
}