{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Negative+Emotions",
    "query": {
      "condition": "Negative Emotions"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 20,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Negative+Emotions&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T08:04:43.778Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05683431",
      "title": "Using Neuroplasticity-Based Computerized Training to Improve Emotion Regulation in Bipolar Disorder (BRAINS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bipolar Disorder",
        "Bipolar I Disorder",
        "Bipolar Affective Disorder",
        "Bipolar Disorder I",
        "Bipolar Depression"
      ],
      "interventions": [
        {
          "name": "Cognitive Control of Emotion (CCE) Training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 12,
      "start_date": "2019-03-22",
      "completion_date": "2021-12-16",
      "has_results": false,
      "last_update_posted_date": "2023-01-13",
      "last_synced_at": "2026-07-23T08:04:43.778Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05683431"
    },
    {
      "nct_id": "NCT04463225",
      "title": "The Network Study: Soldiers Connecting for Work and Health",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alcohol Use Disorder",
        "Depression"
      ],
      "interventions": [
        {
          "name": "Internet-Delivered Brief Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "62 Years",
        "sex": "ALL",
        "summary": "18 Years to 62 Years"
      },
      "enrollment_count": 450,
      "start_date": "2021-03-30",
      "completion_date": "2024-03-31",
      "has_results": false,
      "last_update_posted_date": "2023-05-26",
      "last_synced_at": "2026-07-23T08:04:43.778Z",
      "location_count": 1,
      "location_summary": "Tacoma, Washington",
      "locations": [
        {
          "city": "Tacoma",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04463225"
    },
    {
      "nct_id": "NCT00097175",
      "title": "Effects of Tryptophan Depletion on Brain Processing of Emotions in Patients With Mood Disorders",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Depressive Disorder, Major"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 95,
      "start_date": "2004-11-10",
      "completion_date": "2014-01-15",
      "has_results": false,
      "last_update_posted_date": "2019-12-12",
      "last_synced_at": "2026-07-23T08:04:43.778Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00097175"
    },
    {
      "nct_id": "NCT02736045",
      "title": "Ameliorating Work Burnout and Medical Residents",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Burnout, Professional",
        "Depression",
        "Stress",
        "Anxiety",
        "Distress"
      ],
      "interventions": [
        {
          "name": "emWave",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Larkin Community Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "25 Years to 50 Years"
      },
      "enrollment_count": 0,
      "start_date": "2015-07-01",
      "completion_date": "2016-07-30",
      "has_results": false,
      "last_update_posted_date": "2023-10-16",
      "last_synced_at": "2026-07-23T08:04:43.778Z",
      "location_count": 1,
      "location_summary": "South Miami, Florida",
      "locations": [
        {
          "city": "South Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02736045"
    },
    {
      "nct_id": "NCT00001675",
      "title": "The Effect of Positive and Negative Emotions on Brain Activity in Alcoholics and Nonalcoholics",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alcoholism",
        "Healthy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute on Alcohol Abuse and Alcoholism (NIAAA)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "12 Years to 65 Years"
      },
      "enrollment_count": 1194,
      "start_date": "1998-01-23",
      "completion_date": "2015-12-23",
      "has_results": false,
      "last_update_posted_date": "2019-12-09",
      "last_synced_at": "2026-07-23T08:04:43.778Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00001675"
    },
    {
      "nct_id": "NCT03487822",
      "title": "A Personalized Self-Management Program for Older Adults With Chronic Pain and Negative Emotions",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain, Chronic",
        "Negative Emotions"
      ],
      "interventions": [
        {
          "name": "Path Pain",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 157,
      "start_date": "2017-08-08",
      "completion_date": "2019-07-26",
      "has_results": false,
      "last_update_posted_date": "2024-12-18",
      "last_synced_at": "2026-07-23T08:04:43.778Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03487822"
    },
    {
      "nct_id": "NCT07361731",
      "title": "Evaluating the Feasibility, Acceptability, and Preliminary Outcomes of Heart Rate Variability Biofeedback for Individuals With Opioid Use Disorder.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Autonomic Nervous System Imbalance",
        "Heart Rate Variability (HRV)",
        "Opioid Use Disorder",
        "Breathing Techniques",
        "Opioid Craving",
        "Recovery",
        "Emotional Regulation",
        "Positive and Negative Affect",
        "Stress",
        "Biofeedback"
      ],
      "interventions": [
        {
          "name": "Heart rate variability biofeedback",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Arizona State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 32,
      "start_date": "2025-12-01",
      "completion_date": "2026-02-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-15",
      "last_synced_at": "2026-07-23T08:04:43.778Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07361731"
    },
    {
      "nct_id": "NCT01909895",
      "title": "Study of the Effects of Negative Emotions on Endothelial Function",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Emotions",
        "Endothelial Dysfunction"
      ],
      "interventions": [
        {
          "name": "Anger Induction",
          "type": "OTHER"
        },
        {
          "name": "Depressed Mood Induction",
          "type": "OTHER"
        },
        {
          "name": "Anxiety Induction",
          "type": "OTHER"
        },
        {
          "name": "Neutral emotion task",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 280,
      "start_date": "2013-09-01",
      "completion_date": "2020-11-01",
      "has_results": false,
      "last_update_posted_date": "2022-01-27",
      "last_synced_at": "2026-07-23T08:04:43.778Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01909895"
    },
    {
      "nct_id": "NCT03609671",
      "title": "Emotions Immunology and Breast Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer",
        "Triple Negative Breast Cancer",
        "Emotions",
        "Immunology"
      ],
      "interventions": [
        {
          "name": "Standard of Care + Experimental Individualized Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control: Standard of Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Luz A. Venta, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 17,
      "start_date": "2015-11-23",
      "completion_date": "2019-03-18",
      "has_results": false,
      "last_update_posted_date": "2019-08-28",
      "last_synced_at": "2026-07-23T08:04:43.778Z",
      "location_count": 2,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03609671"
    },
    {
      "nct_id": "NCT03040076",
      "title": "Testing if Reductions in Negative Affect Yield Decreased Emotional Eating Symptoms",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Eating Disorder Symptom",
        "Emotional Maladjustment",
        "Negative Thoughts"
      ],
      "interventions": [
        {
          "name": "Cognitive Bias Treatment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Relaxation Condition",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Florida State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 28,
      "start_date": "2017-03-28",
      "completion_date": "2017-05-03",
      "has_results": false,
      "last_update_posted_date": "2018-06-26",
      "last_synced_at": "2026-07-23T08:04:43.778Z",
      "location_count": 1,
      "location_summary": "Tallahassee, Florida",
      "locations": [
        {
          "city": "Tallahassee",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03040076"
    }
  ]
}