{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neonatal+Encephalopathy%2C+Unspecified",
    "query": {
      "condition": "Neonatal Encephalopathy, Unspecified"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 110,
    "total_pages": 11,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neonatal+Encephalopathy%2C+Unspecified&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-10-08T18:25:16.369Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05013736",
      "title": "Baby Brain Recovery Study",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Perinatal Stroke"
      ],
      "interventions": [
        {
          "name": "Magnetic Resonance Imaging",
          "type": "DEVICE"
        },
        {
          "name": "Behavioral Assessments",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Non invasive Transcranial Magnetic Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Years",
        "maximum_age": "24 Months",
        "sex": "ALL",
        "summary": "0 Years to 24 Months"
      },
      "enrollment_count": 65,
      "start_date": "2022-07-26",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-09-18",
      "last_synced_at": "2026-10-08T18:25:16.369Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05013736"
    },
    {
      "nct_id": "NCT02434965",
      "title": "Autologous Cord Blood and Human Placental Derived Stem Cells in Neonates With Severe Hypoxic-Ischemic Encephalopathy",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Severe Hypoxic-ischemic Encephalopathy"
      ],
      "interventions": [
        {
          "name": "HPDSC",
          "type": "DRUG"
        },
        {
          "name": "Cord blood",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "New York Medical College",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Minute",
        "maximum_age": "6 Hours",
        "sex": "ALL",
        "summary": "1 Minute to 6 Hours"
      },
      "enrollment_count": 0,
      "start_date": "2019-12",
      "completion_date": "2022-01",
      "has_results": false,
      "last_update_posted_date": "2021-02-23",
      "last_synced_at": "2026-10-08T18:25:16.369Z",
      "location_count": 1,
      "location_summary": "Valhalla, New York",
      "locations": [
        {
          "city": "Valhalla",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02434965"
    },
    {
      "nct_id": "NCT06908226",
      "title": "A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathy (DEE)",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Developmental and Epileptic Encephalopathy"
      ],
      "interventions": [
        {
          "name": "LP352",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Longboard Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "66 Years",
        "sex": "ALL",
        "summary": "2 Years to 66 Years"
      },
      "enrollment_count": 324,
      "start_date": "2025-02-12",
      "completion_date": "2027-12-17",
      "has_results": false,
      "last_update_posted_date": "2026-09-15",
      "last_synced_at": "2026-10-08T18:25:16.369Z",
      "location_count": 20,
      "location_summary": "Little Rock, Arkansas • Los Angeles, California • Palo Alto, California + 16 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06908226"
    },
    {
      "nct_id": "NCT03640494",
      "title": "Bedside Optical Retinal Assessment of Hypoxic Ischemic Encephalopathy in Infants",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hypoxic-Ischemic Encephalopathy"
      ],
      "interventions": [
        {
          "name": "Optical Coherence Tomography",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "20 Days",
        "sex": "ALL",
        "summary": "Up to 20 Days"
      },
      "enrollment_count": 57,
      "start_date": "2018-08-28",
      "completion_date": "2021-02-28",
      "has_results": false,
      "last_update_posted_date": "2021-04-08",
      "last_synced_at": "2026-10-08T18:25:16.369Z",
      "location_count": 2,
      "location_summary": "Durham, North Carolina • Salt Lake City, Utah",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03640494"
    },
    {
      "nct_id": "NCT00719407",
      "title": "Neonatal Erythropoietin in Asphyxiated Term Newborns",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Hypoxic-ischemic Encephalopathy"
      ],
      "interventions": [
        {
          "name": "erythropoietin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "24 Hours",
        "sex": "ALL",
        "summary": "Up to 24 Hours"
      },
      "enrollment_count": 24,
      "start_date": "2010-01",
      "completion_date": "2012-11",
      "has_results": false,
      "last_update_posted_date": "2012-11-09",
      "last_synced_at": "2026-10-08T18:25:16.369Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00719407"
    },
    {
      "nct_id": "NCT02529202",
      "title": "Dexmedetomidine Pharmacokinetics in Neonates During Therapeutic Hypothermia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Hypoxic-ischemic Encephalopathy"
      ],
      "interventions": [
        {
          "name": "Dexmedetomidine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Seattle Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Hour",
        "maximum_age": "1 Day",
        "sex": "ALL",
        "summary": "1 Hour to 1 Day"
      },
      "enrollment_count": 7,
      "start_date": "2016-03",
      "completion_date": "2017-01",
      "has_results": false,
      "last_update_posted_date": "2017-01-12",
      "last_synced_at": "2026-10-08T18:25:16.369Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02529202"
    },
    {
      "nct_id": "NCT06429007",
      "title": "A Safety and Feasibility Trial Protocol of Metformin in Infants After Perinatal Brain Injury",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Hypoxic-Ischemic Encephalopathy",
        "HIE",
        "Neurodevelopment",
        "Infant Development"
      ],
      "interventions": [
        {
          "name": "Metformin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Months",
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "3 Months to 6 Months"
      },
      "enrollment_count": 30,
      "start_date": "2025-10-01",
      "completion_date": "2029-03-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-17",
      "last_synced_at": "2026-10-08T18:25:16.369Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06429007"
    },
    {
      "nct_id": "NCT05364021",
      "title": "Study to Investigate LP352 in Subjects With Developmental and Epileptic Encephalopathies",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Developmental and Epileptic Encephalopathy",
        "Dravet Syndrome",
        "Lennox Gastaut Syndrome"
      ],
      "interventions": [
        {
          "name": "LP352",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Longboard Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "12 Years to 65 Years"
      },
      "enrollment_count": 52,
      "start_date": "2022-03-03",
      "completion_date": "2023-11-20",
      "has_results": false,
      "last_update_posted_date": "2024-11-08",
      "last_synced_at": "2026-10-08T18:25:16.369Z",
      "location_count": 29,
      "location_summary": "Tucson, Arizona • Little Rock, Arkansas • Downey, California + 24 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Downey",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05364021"
    },
    {
      "nct_id": "NCT06448780",
      "title": "Dose Optimization of Caffeine for HIE",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Hypoxic-Ischemic Encephalopathy"
      ],
      "interventions": [
        {
          "name": "Caffeine citrate 20 mg/kg",
          "type": "DRUG"
        },
        {
          "name": "Caffeine citrate 30 mg/kg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "24 Hours",
        "sex": "ALL",
        "summary": "Up to 24 Hours"
      },
      "enrollment_count": 16,
      "start_date": "2024-07-26",
      "completion_date": "2028-07",
      "has_results": false,
      "last_update_posted_date": "2026-08-14",
      "last_synced_at": "2026-10-08T18:25:16.369Z",
      "location_count": 2,
      "location_summary": "Chapel Hill, North Carolina • Wilmington, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "Wilmington",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06448780"
    },
    {
      "nct_id": "NCT00515359",
      "title": "RCT for Intermittent Versus Continuous Propofol Sedation for Pediatric Brain and Spine MRI Studies",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Encephalopathy",
        "Developmental Delay and Behavioral Changes",
        "Cord Tumor Compression or Instability",
        "Cord Tethering or Malformation"
      ],
      "interventions": [
        {
          "name": "Intermittent Propofol Sedation",
          "type": "PROCEDURE"
        },
        {
          "name": "Continuous Propofol Sedation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Corewell Health West",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "1 Month to 18 Years"
      },
      "enrollment_count": 276,
      "start_date": "2007-06",
      "completion_date": "2009-02",
      "has_results": false,
      "last_update_posted_date": "2024-01-19",
      "last_synced_at": "2026-10-08T18:25:16.369Z",
      "location_count": 1,
      "location_summary": "Grand Rapids, Michigan",
      "locations": [
        {
          "city": "Grand Rapids",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00515359"
    }
  ]
}