{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neonatal+Necrotizing+Enterocolitis&page=2",
    "query": {
      "condition": "Neonatal Necrotizing Enterocolitis",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neonatal+Necrotizing+Enterocolitis&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T23:02:49.811Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01029353",
      "title": "Laparotomy vs. Drainage for Infants With Necrotizing Enterocolitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infant, Newborn",
        "Infant, Low Birth Weight",
        "Infant, Small for Gestational Age",
        "Infant, Premature",
        "Enterocolitis, Necrotizing",
        "Intestinal Perforation"
      ],
      "interventions": [
        {
          "name": "Laparotomy",
          "type": "PROCEDURE"
        },
        {
          "name": "Drainage",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "8 Weeks",
        "sex": "ALL",
        "summary": "Up to 8 Weeks"
      },
      "enrollment_count": 529,
      "start_date": "2010-01",
      "completion_date": "2019-08",
      "has_results": true,
      "last_update_posted_date": "2024-07-18",
      "last_synced_at": "2026-07-22T23:02:49.811Z",
      "location_count": 22,
      "location_summary": "Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 18 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01029353"
    },
    {
      "nct_id": "NCT02477423",
      "title": "A Randomized Controlled Trial Investigating if Antibiotic Use in the First 48 Hours of Life Adversely Impacts the Preterm Infant Microbiome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premature Birth of Newborn",
        "Enterocolitis, Necrotizing"
      ],
      "interventions": [
        {
          "name": "Ampicillin",
          "type": "DRUG"
        },
        {
          "name": "Gentamicins",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "6 Hours",
        "sex": "ALL",
        "summary": "Up to 6 Hours"
      },
      "enrollment_count": 27,
      "start_date": "2015-07",
      "completion_date": "2019-06",
      "has_results": true,
      "last_update_posted_date": "2020-10-08",
      "last_synced_at": "2026-07-22T23:02:49.811Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02477423"
    },
    {
      "nct_id": "NCT01106209",
      "title": "Neutrophil Extracellular Trap Formation in Newborn Infants at Risk for Inflammatory Syndromes",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Prematurity",
        "Necrotizing Enterocolitis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Year",
        "sex": "ALL",
        "summary": "Up to 1 Year"
      },
      "enrollment_count": 14,
      "start_date": "2010-04",
      "completion_date": "2020-06-22",
      "has_results": true,
      "last_update_posted_date": "2025-03-18",
      "last_synced_at": "2026-07-22T23:02:49.811Z",
      "location_count": 2,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01106209"
    },
    {
      "nct_id": "NCT00392730",
      "title": "Neurodevelopment and Neuroimaging in Parenterally-fed Infants and Young Children",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Parenteral Nutrition",
        "Necrotizing Enterocolitis",
        "Digestive System Abnormalities",
        "Cholestasis"
      ],
      "interventions": [
        {
          "name": "Remove Mn from PN if evidence of increased brain Mn on MRI",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Days",
        "maximum_age": "6 Years",
        "sex": "ALL",
        "summary": "30 Days to 6 Years"
      },
      "enrollment_count": 122,
      "start_date": "2006-08",
      "completion_date": "2010-12",
      "has_results": false,
      "last_update_posted_date": "2013-12-19",
      "last_synced_at": "2026-07-22T23:02:49.811Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00392730"
    },
    {
      "nct_id": "NCT00005888",
      "title": "Study of the Relationship Between Feeding and Late Onset Sepsis and/or Necrotizing Enterocolitis in Low Birth Weight Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Necrotizing Enterocolitis",
        "Sepsis"
      ],
      "interventions": [
        {
          "name": "Fortified Pasteurized Donor Human Milk supplement",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Preterm Formula supplement",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "National Center for Research Resources (NCRR)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Years",
        "maximum_age": "96 Hours",
        "sex": "ALL",
        "summary": "0 Years to 96 Hours"
      },
      "enrollment_count": 300,
      "start_date": "1997-01",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2005-06-24",
      "last_synced_at": "2026-07-22T23:02:49.811Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00005888"
    },
    {
      "nct_id": "NCT00828451",
      "title": "Collaborative Research Group for Necrotizing Enterocolitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prematurity",
        "Necrotizing Enterocolitis"
      ],
      "interventions": [
        {
          "name": "[5,5,5-2H3]leucine (stable isotope labeled leucine)",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "7 Days",
        "sex": "ALL",
        "summary": "1 Day to 7 Days"
      },
      "enrollment_count": 29,
      "start_date": "2008-05",
      "completion_date": "2010-12",
      "has_results": true,
      "last_update_posted_date": "2018-04-04",
      "last_synced_at": "2026-07-22T23:02:49.811Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00828451"
    },
    {
      "nct_id": "NCT00392977",
      "title": "Brain Manganese Deposition in High Risk Neonates",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Necrotizing Enterocolitis",
        "Digestive System Abnormalities",
        "Cholestasis"
      ],
      "interventions": [
        {
          "name": "remove Mn from PN if evidence of increased brain Mn on MRI",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Days",
        "maximum_age": "12 Months",
        "sex": "ALL",
        "summary": "30 Days to 12 Months"
      },
      "enrollment_count": 43,
      "start_date": "2006-08",
      "completion_date": "2010-12",
      "has_results": false,
      "last_update_posted_date": "2013-12-19",
      "last_synced_at": "2026-07-22T23:02:49.811Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00392977"
    },
    {
      "nct_id": "NCT07254559",
      "title": "Integrated Predictive Monitoring for Sepsis and Necrotizing Enterocolitis",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sepsis",
        "Necrotising Enterocolitis Neonatal"
      ],
      "interventions": [
        {
          "name": "No Intervention: Observational Cohort",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 144,
      "start_date": "2024-01-01",
      "completion_date": "2024-10-31",
      "has_results": true,
      "last_update_posted_date": "2026-02-17",
      "last_synced_at": "2026-07-22T23:02:49.811Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07254559"
    },
    {
      "nct_id": "NCT01126372",
      "title": "Prediction of Feeding Problems in Prostaglandin-dependent Prematurely Born Infants With Congenital Heart Disease",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Congenital Heart Disease",
        "Prematurity",
        "Necrotizing Enterocolitis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Month",
        "sex": "ALL",
        "summary": "Up to 1 Month"
      },
      "enrollment_count": 6,
      "start_date": "2010-05",
      "completion_date": "2013-06",
      "has_results": false,
      "last_update_posted_date": "2013-08-13",
      "last_synced_at": "2026-07-22T23:02:49.811Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01126372"
    },
    {
      "nct_id": "NCT02116699",
      "title": "Oropharyngeal Administration of Mother's Colostrum for Premature Infants (NS-72393-360)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infection",
        "Enterocolitis, Necrotizing",
        "Ventilator-associated Pneumonia"
      ],
      "interventions": [
        {
          "name": "oropharyngeal mother's milk",
          "type": "OTHER"
        },
        {
          "name": "oropharyngeal sterile water",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Endeavor Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "4 Days",
        "sex": "ALL",
        "summary": "1 Day to 4 Days"
      },
      "enrollment_count": 260,
      "start_date": "2013-11-20",
      "completion_date": "2022-01-04",
      "has_results": false,
      "last_update_posted_date": "2023-03-01",
      "last_synced_at": "2026-07-22T23:02:49.811Z",
      "location_count": 5,
      "location_summary": "Miami, Florida • Evanston, Illinois • Park Ridge, Illinois + 2 more",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Evanston",
          "state": "Illinois"
        },
        {
          "city": "Park Ridge",
          "state": "Illinois"
        },
        {
          "city": "Morristown",
          "state": "New Jersey"
        },
        {
          "city": "Wilmington",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02116699"
    }
  ]
}