{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neonatal+Respiratory+Failure&page=2",
    "query": {
      "condition": "Neonatal Respiratory Failure",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neonatal+Respiratory+Failure&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T09:46:30.113Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00609882",
      "title": "Comparison of Humidified High Flow Nasal Cannula to Nasal CPAP in Neonates",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Insufficiency"
      ],
      "interventions": [
        {
          "name": "Nasal CPAP",
          "type": "OTHER"
        },
        {
          "name": "Humidified High Flow Nasal Cannula (HHFNC)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "8 Weeks",
        "sex": "ALL",
        "summary": "Up to 8 Weeks"
      },
      "enrollment_count": 420,
      "start_date": "2007-12",
      "completion_date": "2012-06",
      "has_results": false,
      "last_update_posted_date": "2013-02-06",
      "last_synced_at": "2026-05-22T09:46:30.113Z",
      "location_count": 8,
      "location_summary": "Philadelphia, Pennsylvania • Lackland Air Force Base, Texas • Ogden, Utah + 3 more",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Lackland Air Force Base",
          "state": "Texas"
        },
        {
          "city": "Ogden",
          "state": "Utah"
        },
        {
          "city": "Provo",
          "state": "Utah"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00609882"
    },
    {
      "nct_id": "NCT05446272",
      "title": "The Diaphragmatic Initiated Ventilatory Assist (DIVA) Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Extubation Failure",
        "Bronchopulmonary Dysplasia",
        "Death"
      ],
      "interventions": [
        {
          "name": "NIV-NAVA",
          "type": "DEVICE"
        },
        {
          "name": "NS-NIPPV",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Days",
        "maximum_age": "9 Weeks",
        "sex": "ALL",
        "summary": "0 Days to 9 Weeks"
      },
      "enrollment_count": 478,
      "start_date": "2022-08-03",
      "completion_date": "2027-03-31",
      "has_results": false,
      "last_update_posted_date": "2025-10-07",
      "last_synced_at": "2026-05-22T09:46:30.113Z",
      "location_count": 17,
      "location_summary": "Little Rock, Arkansas • Loma Linda, California • San Diego, California + 14 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Hollywood",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05446272"
    },
    {
      "nct_id": "NCT02582957",
      "title": "Sigh Ventilation to Increase Ventilator-Free Days in Victims of Trauma at Risk for Acute Respiratory Distress Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Respiratory Distress Syndrome"
      ],
      "interventions": [
        {
          "name": "Sigh breaths",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 524,
      "start_date": "2016-04-01",
      "completion_date": "2022-10-08",
      "has_results": true,
      "last_update_posted_date": "2024-06-06",
      "last_synced_at": "2026-05-22T09:46:30.113Z",
      "location_count": 15,
      "location_summary": "Fresno, California • Los Angeles, California • Sacramento, California + 12 more",
      "locations": [
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Newark",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02582957"
    },
    {
      "nct_id": "NCT01859065",
      "title": "\"Anticipatory Guidance in the Nursery and Its Impact on Non-urgent Emergency Department Visits\"",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Health Knowledge, Attitudes, Practice",
        "Sneezing",
        "Constipation",
        "Nasal Congestion and Inflammations"
      ],
      "interventions": [
        {
          "name": "Intensified anticipatory guidance",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Routine",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Bronx-Lebanon Hospital Center Health Care System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 323,
      "start_date": "2011-12",
      "completion_date": "2012-04",
      "has_results": false,
      "last_update_posted_date": "2013-05-21",
      "last_synced_at": "2026-05-22T09:46:30.113Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01859065"
    },
    {
      "nct_id": "NCT05462600",
      "title": "Distribution of Ventilation, Respiratory Drive and Gas Exchange: Measurements and Monitoring",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pulmonary Disease",
        "Respiratory System Abnormalities",
        "OSA",
        "Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "Position change",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2022-07-19",
      "completion_date": "2026-12-30",
      "has_results": false,
      "last_update_posted_date": "2025-04-11",
      "last_synced_at": "2026-05-22T09:46:30.113Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05462600"
    },
    {
      "nct_id": "NCT01424696",
      "title": "Baby Observational and Nutritional Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cystic Fibrosis",
        "Growth Failure",
        "Exocrine Pancreatic Insufficiency"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Seattle Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "3 Months",
        "sex": "ALL",
        "summary": "Up to 3 Months"
      },
      "enrollment_count": 231,
      "start_date": "2011-12",
      "completion_date": "2015-04",
      "has_results": false,
      "last_update_posted_date": "2015-09-28",
      "last_synced_at": "2026-05-22T09:46:30.113Z",
      "location_count": 28,
      "location_summary": "Birmingham, Alabama • Little Rock, Arkansas • Aurora, Colorado + 24 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01424696"
    },
    {
      "nct_id": "NCT00011362",
      "title": "Dexamethasone Therapy in VLBW Infants at Risk of CLD",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Infant, Newborn",
        "Infant, Low Birth Weight",
        "Infant, Small for Gestational Age",
        "Infant, Premature",
        "Bronchopulmonary Dysplasia"
      ],
      "interventions": [
        {
          "name": "Dexamethasone Early",
          "type": "DRUG"
        },
        {
          "name": "Dexamethasone Late",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Days",
        "maximum_age": "15 Days",
        "sex": "ALL",
        "summary": "13 Days to 15 Days"
      },
      "enrollment_count": 371,
      "start_date": "1992-09",
      "completion_date": "1994-04",
      "has_results": false,
      "last_update_posted_date": "2019-03-22",
      "last_synced_at": "2026-05-22T09:46:30.113Z",
      "location_count": 13,
      "location_summary": "Palo Alto, California • New Haven, Connecticut • Washington D.C., District of Columbia + 10 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00011362"
    },
    {
      "nct_id": "NCT05451953",
      "title": "Providing Oxygen During Intubation in the NICU Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neonatal Respiratory Failure",
        "Tracheal Intubation Morbidity"
      ],
      "interventions": [
        {
          "name": "Apneic Oxygenation",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard of Care",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Days",
        "maximum_age": "365 Days",
        "sex": "ALL",
        "summary": "0 Days to 365 Days"
      },
      "enrollment_count": 110,
      "start_date": "2022-07-20",
      "completion_date": "2027-02-28",
      "has_results": false,
      "last_update_posted_date": "2025-06-18",
      "last_synced_at": "2026-05-22T09:46:30.113Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05451953"
    },
    {
      "nct_id": "NCT00433212",
      "title": "Nasal Intermittent Positive Pressure Ventilation in Premature Infants (NIPPV)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Respiratory Insufficiency of Prematurity"
      ],
      "interventions": [
        {
          "name": "nCPAP",
          "type": "DEVICE"
        },
        {
          "name": "NIPPV",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "McMaster University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "28 Days",
        "sex": "ALL",
        "summary": "Up to 28 Days"
      },
      "enrollment_count": 1011,
      "start_date": "2007-04",
      "completion_date": "2011-12",
      "has_results": false,
      "last_update_posted_date": "2014-12-05",
      "last_synced_at": "2026-05-22T09:46:30.113Z",
      "location_count": 14,
      "location_summary": "Washington D.C., District of Columbia • Boston, Massachusetts • Voorhees Township, New Jersey + 6 more",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Voorhees Township",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00433212"
    },
    {
      "nct_id": "NCT02951130",
      "title": "Milrinone in Congenital Diaphragmatic Hernia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Congenital Diaphragmatic Hernia",
        "Persistent Pulmonary Hypertension of the Newborn",
        "Hypoxemic Respiratory Failure",
        "Pulmonary Hypoplasia"
      ],
      "interventions": [
        {
          "name": "Milrinone",
          "type": "DRUG"
        },
        {
          "name": "Placebo (5% Dextrose)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Hours",
        "maximum_age": "168 Hours",
        "sex": "ALL",
        "summary": "0 Hours to 168 Hours"
      },
      "enrollment_count": 66,
      "start_date": "2017-10-24",
      "completion_date": "2025-05-19",
      "has_results": true,
      "last_update_posted_date": "2025-11-06",
      "last_synced_at": "2026-05-22T09:46:30.113Z",
      "location_count": 19,
      "location_summary": "Birmingham, Alabama • Palo Alto, California • Atlanta, Georgia + 15 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Kansas City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02951130"
    }
  ]
}