{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neoplasm%2C+Unknown+Primary", "query": { "condition": "Neoplasm, Unknown Primary" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 98, "total_pages": 10, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neoplasm%2C+Unknown+Primary&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-03T22:11:17.699Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03258554", "title": "Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8", "Head and Neck Squamous Cell Carcinoma", "Hypopharyngeal Squamous Cell Carcinoma", "Laryngeal Squamous Cell Carcinoma", "Oral Cavity Squamous Cell Carcinoma", "Oropharyngeal Squamous Cell Carcinoma", "Pathologic Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8", "Squamous Cell Carcinoma of Unknown Primary", "Stage III Hypopharyngeal Carcinoma AJCC v8", "Stage III Laryngeal Cancer AJCC v8", "Stage III Lip and Oral Cavity Cancer AJCC v8", "Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8", "Stage IVA Hypopharyngeal Carcinoma AJCC v8", "Stage IVA Laryngeal Cancer AJCC v8", "Stage IVA Lip and Oral Cavity Cancer AJCC v8", "Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8", "Stage IVB Hypopharyngeal Carcinoma AJCC v8", "Stage IVB Laryngeal Cancer AJCC v8", "Stage IVB Lip and Oral Cavity Cancer AJCC v8", "Stage IVB Oropharyngeal (p16-Negative) Carcinoma AJCC v8" ], "interventions": [ { "name": "Cetuximab", "type": "BIOLOGICAL" }, { "name": "Durvalumab", "type": "BIOLOGICAL" }, { "name": "Intensity-Modulated Radiation Therapy", "type": "RADIATION" }, { "name": "Laboratory Biomarker Analysis", "type": "OTHER" }, { "name": "Quality-of-Life Assessment", "type": "OTHER" }, { "name": "Questionnaire Administration", "type": "OTHER" } ], "intervention_types": [ "BIOLOGICAL", "RADIATION", "OTHER" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 196, "start_date": "2018-04-03", "completion_date": "2025-09-04", "has_results": true, "last_update_posted_date": "2026-08-27", "last_synced_at": "2026-09-03T22:11:17.699Z", "location_count": 252, "location_summary": "Birmingham, Alabama • Mobile, Alabama • Gilbert, Arizona + 193 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Gilbert", "state": "Arizona" }, { "city": "Goodyear", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT03258554" }, { "nct_id": "NCT02834013", "title": "Nivolumab and Ipilimumab in Treating Patients With Rare Tumors", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Acinar Cell Carcinoma", "Adenoid Cystic Carcinoma", "Adrenal Cortical Carcinoma", "Adrenal Gland Pheochromocytoma", "Anal Canal Neuroendocrine Carcinoma", "Anal Canal Undifferentiated Carcinoma", "Angiosarcoma", "Apocrine Neoplasm", "Appendix Mucinous Adenocarcinoma", "Bartholin Gland Transitional Cell Carcinoma", "Basal Cell Carcinoma", "Bladder Adenocarcinoma", "Breast Metaplastic Carcinoma", "Cervical Adenocarcinoma", "Cholangiocarcinoma", "Chordoma", "Colorectal Squamous Cell Carcinoma", "Desmoid Fibromatosis", "Endometrial Transitional Cell Carcinoma", "Endometrioid Adenocarcinoma", "Esophageal Neuroendocrine Carcinoma", "Esophageal Undifferentiated Carcinoma", "Extrahepatic Bile Duct Carcinoma", "Extramammary Paget Disease", "Fallopian Tube Adenocarcinoma", "Fallopian Tube Transitional Cell Carcinoma", "Fibromyxoid Tumor", "Gallbladder Carcinoma", "Gastric Neuroendocrine Carcinoma", "Gastric Squamous Cell Carcinoma", "Gastric Undifferentiated Carcinoma", "Gastrointestinal Stromal Tumor", "Gestational Trophoblastic Tumor", "Giant Cell Carcinoma", "Human Papillomavirus-Independent Cervical Adenocarcinoma, Clear Cell-Type", "Intestinal Neuroendocrine Carcinoma", "Intrahepatic Cholangiocarcinoma", "Lung Neuroendocrine Tumor", "Lung Sarcomatoid Carcinoma", "Major Salivary Gland Carcinoma", "Malignant Neoplasm of Unknown Primary", "Malignant Odontogenic Neoplasm", "Malignant Peripheral Nerve Sheath Tumor", "Malignant Solid Neoplasm", "Malignant Testicular Sex Cord-Stromal Tumor", "Metastatic Pituitary Neuroendocrine Tumor", "Minimally Invasive Lung Adenocarcinoma", "Mixed Mesodermal (Mullerian) Tumor", "Mucinous Adenocarcinoma", "Mucinous Cystadenocarcinoma", "Nasal Cavity Adenocarcinoma", "Nasal Cavity Carcinoma", "Nasopharyngeal Carcinoma", "Nasopharyngeal Low Grade Papillary Adenocarcinoma", "Nasopharyngeal Undifferentiated Carcinoma", "Oral Cavity Carcinoma", "Oropharyngeal Undifferentiated Carcinoma", "Ovarian Adenocarcinoma", "Ovarian Germ Cell Tumor", "Ovarian Mucinous Adenocarcinoma", "Ovarian Squamous Cell Carcinoma", "Ovarian Transitional Cell Carcinoma", "Pancreatic Acinar Cell Carcinoma", "Pancreatic Neuroendocrine Carcinoma", "Paraganglioma", "Paranasal Sinus Adenocarcinoma", "Paranasal Sinus Carcinoma", "Parathyroid Gland Carcinoma", "PEComa", "Penile Squamous Cell Carcinoma", "Peritoneal Mesothelial Neoplasm", "Placental Choriocarcinoma", "Primary Peritoneal High Grade Serous Adenocarcinoma", "Pseudomyxoma Peritonei", "Rare Disorder", "Scrotal Squamous Cell Carcinoma", "Seminal Vesicle Adenocarcinoma", "Seminoma", "Serous Cystadenocarcinoma", "Small Intestinal Adenocarcinoma", "Small Intestinal Squamous Cell Carcinoma", "Spindle Cell Neoplasm", "Teratoma With Somatic-Type Malignancy", "Testicular Non-Seminomatous Germ Cell Tumor", "Thyroid Gland Carcinoma", "Tracheal Carcinoma", "Transitional Cell Carcinoma", "Ureter Adenocarcinoma", "Ureter Squamous Cell Carcinoma", "Urethral Adenocarcinoma", "Urethral Squamous Cell Carcinoma", "Vaginal Adenocarcinoma", "Vaginal Squamous Cell Carcinoma, Not Otherwise Specified", "Vulvar Carcinoma" ], "interventions": [ { "name": "Biospecimen Collection", "type": "PROCEDURE" }, { "name": "Computed Tomography", "type": "PROCEDURE" }, { "name": "Echocardiography Test", "type": "PROCEDURE" }, { "name": "Ipilimumab", "type": "BIOLOGICAL" }, { "name": "Magnetic Resonance Imaging", "type": "PROCEDURE" }, { "name": "Nivolumab", "type": "BIOLOGICAL" } ], "intervention_types": [ "PROCEDURE", "BIOLOGICAL" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 798, "start_date": "2017-01-30", "completion_date": "2027-06-01", "has_results": false, "last_update_posted_date": "2026-06-17", "last_synced_at": "2026-09-03T22:11:17.699Z", "location_count": 1006, "location_summary": "Birmingham, Alabama • Mobile, Alabama • Anchorage, Alaska + 620 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Anchorage", "state": "Alaska" }, { "city": "Anchorage", "state": "Alaska" }, { "city": "Anchorage", "state": "Alaska" } ], "official_url": "https://clinicaltrials.gov/study/NCT02834013" }, { "nct_id": "NCT03396471", "title": "Study of Pembrolizumab and Concurrent Radiation in Patients With Previously Treated Carcinoma of Unknown Primary", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Carcinoma, Unspecified Site" ], "interventions": [ { "name": "Pembrolizumab", "type": "DRUG" }, { "name": "External Beam Radiation Therapy", "type": "RADIATION" } ], "intervention_types": [ "DRUG", "RADIATION" ], "sponsor": "Hoosier Cancer Research Network", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 14, "start_date": "2018-02-01", "completion_date": "2023-03-02", "has_results": true, "last_update_posted_date": "2024-04-18", "last_synced_at": "2026-09-03T22:11:17.699Z", "location_count": 2, "location_summary": "Rochester, Minnesota • Houston, Texas", "locations": [ { "city": "Rochester", "state": "Minnesota" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03396471" }, { "nct_id": "NCT03323463", "title": "Major De-escalation to 30 Gy for Select Human Papillomavirus Associated Oropharyngeal Carcinoma", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "HPV-Associated Oropharyngeal Squamous Cell Carcinoma", "Squamous Cell Carcinoma of the Neck" ], "interventions": [ { "name": "F-FMISO PET/CT Scan", "type": "DIAGNOSTIC_TEST" }, { "name": "30 Gy over 3 weeks", "type": "RADIATION" }, { "name": "Cisplatin", "type": "DRUG" }, { "name": "Carboplatin", "type": "DRUG" }, { "name": "5Fluorouracil", "type": "DRUG" }, { "name": "Proton Therapy", "type": "RADIATION" } ], "intervention_types": [ "DIAGNOSTIC_TEST", "RADIATION", "DRUG" ], "sponsor": "Memorial Sloan Kettering Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 316, "start_date": "2017-10-16", "completion_date": "2026-10-31", "has_results": false, "last_update_posted_date": "2026-04-13", "last_synced_at": "2026-09-03T22:11:17.699Z", "location_count": 10, "location_summary": "Hartford, Connecticut • Miami, Florida • Basking Ridge, New Jersey + 7 more", "locations": [ { "city": "Hartford", "state": "Connecticut" }, { "city": "Miami", "state": "Florida" }, { "city": "Basking Ridge", "state": "New Jersey" }, { "city": "Middletown", "state": "New Jersey" }, { "city": "Montvale", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT03323463" }, { "nct_id": "NCT01793168", "title": "Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Rare Disorders", "Undiagnosed Disorders", "Disorders of Unknown Prevalence", "Cornelia De Lange Syndrome", "Prenatal Benign Hypophosphatasia", "Perinatal Lethal Hypophosphatasia", "Odontohypophosphatasia", "Adult Hypophosphatasia", "Childhood-onset Hypophosphatasia", "Infantile Hypophosphatasia", "Hypophosphatasia", "Kabuki Syndrome", "Bohring-Opitz Syndrome", "Narcolepsy Without Cataplexy", "Narcolepsy-cataplexy", "Hypersomnolence Disorder", "Idiopathic Hypersomnia Without Long Sleep Time", "Idiopathic Hypersomnia With Long Sleep Time", "Idiopathic Hypersomnia", "Kleine-Levin Syndrome", "Kawasaki Disease", "Leiomyosarcoma", "Leiomyosarcoma of the Corpus Uteri", "Leiomyosarcoma of the Cervix Uteri", "Leiomyosarcoma of Small Intestine", "Acquired Myasthenia Gravis", "Addison Disease", "Hyperacusis (Hyperacousis)", "Juvenile Myasthenia Gravis", "Transient Neonatal Myasthenia Gravis", "Williams Syndrome", "Lyme Disease", "Myasthenia Gravis", "Marinesco Sjogren Syndrome(Marinesco-Sjogren Syndrome)", "Isolated Klippel-Feil Syndrome", "Frasier Syndrome", "Denys-Drash Syndrome", "Beckwith-Wiedemann Syndrome", "Emanuel Syndrome", "Isolated Aniridia", "Axenfeld-Rieger Syndrome", "Aniridia-intellectual Disability Syndrome", "Aniridia - Renal Agenesis - Psychomotor Retardation", "Aniridia - Ptosis - Intellectual Disability - Familial Obesity", "Aniridia - Cerebellar Ataxia - Intellectual Disability", "Aniridia - Absent Patella", "Aniridia", "Peters Anomaly - Cataract", "Peters Anomaly", "Potocki-Shaffer Syndrome", "Silver-Russell Syndrome Due to Maternal Uniparental Disomy of Chromosome 11", "Silver-Russell Syndrome Due to Imprinting Defect of 11p15", "Silver-Russell Syndrome Due to 11p15 Microduplication", "Syndromic Aniridia", "WAGR Syndrome", "Wolf-Hirschhorn Syndrome", "4p16.3 Microduplication Syndrome", "4p Deletion Syndrome, Non-Wolf-Hirschhorn Syndrome", "Autosomal Recessive Stickler Syndrome", "Stickler Syndrome Type 2", "Stickler Syndrome Type 1", "Stickler Syndrome", "Mucolipidosis Type 4", "X-linked Spinocerebellar Ataxia Type 4", "X-linked Spinocerebellar Ataxia Type 3", "X-linked Intellectual Disability - Ataxia - Apraxia", "X-linked Progressive Cerebellar Ataxia", "X-linked Non Progressive Cerebellar Ataxia", "X-linked Cerebellar Ataxia", "Vitamin B12 Deficiency Ataxia", "Toxic Exposure Ataxia", "Unclassified Autosomal Dominant Spinocerebellar Ataxia", "Thyroid Antibody Ataxia", "Sporadic Adult-onset Ataxia of Unknown Etiology", "Spinocerebellar Ataxia With Oculomotor Anomaly", "Spinocerebellar Ataxia With Epilepsy", "Spinocerebellar Ataxia With Axonal Neuropathy Type 2", "Spinocerebellar Ataxia Type 8", "Spinocerebellar Ataxia Type 7", "Spinocerebellar Ataxia Type 6", "Spinocerebellar Ataxia Type 5", "Spinocerebellar Ataxia Type 4", "Spinocerebellar Ataxia Type 37", "Spinocerebellar Ataxia Type 36", "Spinocerebellar Ataxia Type 35", "Spinocerebellar Ataxia Type 34", "Spinocerebellar Ataxia Type 32", "Spinocerebellar Ataxia Type 31", "Spinocerebellar Ataxia Type 30", "Spinocerebellar Ataxia Type 3", "Spinocerebellar Ataxia Type 29", "Spinocerebellar Ataxia Type 28", "Spinocerebellar Ataxia Type 27", "Spinocerebellar Ataxia Type 26", "Spinocerebellar Ataxia Type 25", "Spinocerebellar Ataxia Type 23", "Spinocerebellar Ataxia Type 22", "Spinocerebellar Ataxia Type 21", "Spinocerebellar Ataxia Type 20", "Spinocerebellar Ataxia Type 2", "Spinocerebellar Ataxia Type 19/22", "Spinocerebellar Ataxia Type 18", "Spinocerebellar Ataxia Type 17", "Spinocerebellar Ataxia Type 16", "Spinocerebellar Ataxia Type 15/16", "Spinocerebellar Ataxia Type 14", "Spinocerebellar Ataxia Type 13", "Spinocerebellar Ataxia Type 12", "Spinocerebellar Ataxia Type 11", "Spinocerebellar Ataxia Type 10", "Spinocerebellar Ataxia Type 1 With Axonal Neuropathy", "Spinocerebellar Ataxia Type 1", "Spinocerebellar Ataxia - Unknown", "Spinocerebellar Ataxia - Dysmorphism", "Non Progressive Epilepsy and/or Ataxia With Myoclonus as a Major Feature", "Spasticity-ataxia-gait Anomalies Syndrome", "Spastic Ataxia With Congenital Miosis", "Spastic Ataxia - Corneal Dystrophy", "Spastic Ataxia", "Rare Hereditary Ataxia", "Rare Ataxia", "Recessive Mitochondrial Ataxia Syndrome", "Progressive Epilepsy and/or Ataxia With Myoclonus as a Major Feature", "Posterior Column Ataxia - Retinitis Pigmentosa", "Post-Stroke Ataxia", "Post-Head Injury Ataxia", "Post Vaccination Ataxia", "Polyneuropathy - Hearing Loss - Ataxia - Retinitis Pigmentosa - Cataract", "Muscular Atrophy - Ataxia - Retinitis Pigmentosa - Diabetes Mellitus", "Non-hereditary Degenerative Ataxia", "Paroxysmal Dystonic Choreathetosis With Episodic Ataxia and Spasticity", "Olivopontocerebellar Atrophy - Deafness", "NARP Syndrome", "Myoclonus - Cerebellar Ataxia - Deafness", "Multiple System Atrophy, Parkinsonian Type", "Multiple System Atrophy, Cerebellar Type", "Multiple System Atrophy", "Maternally-inherited Leigh Syndrome", "Machado-Joseph Disease Type 3", "Machado-Joseph Disease Type 2", "Machado-Joseph Disease Type 1", "Leigh Syndrome", "Late-onset Ataxia With Dementia", "Infection or Post Infection Ataxia", "GAD Ataxia", "Hereditary Episodic Ataxia", "Gliadin/Gluten Ataxia", "Friedreich Ataxia", "Fragile X-associated Tremor/Ataxia Syndrome", "Familial Paroxysmal Ataxia", "Exposure to Medications Ataxia", "Episodic Ataxia With Slurred Speech", "Episodic Ataxia Unknown Type", "Episodic Ataxia Type 7", "Episodic Ataxia Type 6", "Episodic Ataxia Type 5", "Episodic Ataxia Type 4", "Episodic Ataxia Type 3", "Episodic Ataxia Type 1", "Epilepsy and/or Ataxia With Myoclonus as Major Feature", "Early-onset Spastic Ataxia-neuropathy Syndrome", "Early-onset Progressive Neurodegeneration - Blindness - Ataxia - Spasticity", "Early-onset Cerebellar Ataxia With Retained Tendon Reflexes", "Early-onset Ataxia With Dementia", "Childhood-onset Autosomal Recessive Slowly Progressive Spinocerebellar Ataxia", "Dilated Cardiomyopathy With Ataxia", "Cataract - Ataxia - Deafness", "Cerebellar Ataxia, Cayman Type", "Cerebellar Ataxia With Peripheral Neuropathy", "Cerebellar Ataxia - Hypogonadism", "Cerebellar Ataxia - Ectodermal Dysplasia", "Cerebellar Ataxia - Areflexia - Pes Cavus - Optic Atrophy - Sensorineural Hearing Loss", "Brain Tumor Ataxia", "Brachydactyly - Nystagmus - Cerebellar Ataxia", "Benign Paroxysmal Tonic Upgaze of Childhood With Ataxia", "Autosomal Recessive Syndromic Cerebellar Ataxia", "Autosomal Recessive Spastic Ataxia With Leukoencephalopathy", "Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay", "Autosomal Recessive Spastic Ataxia - Optic Atrophy - Dysarthria", "Autosomal Recessive Spastic Ataxia", "Autosomal Recessive Metabolic Cerebellar Ataxia", "Autosomal Dominant Spinocerebellar Ataxia Due to Repeat Expansions That do Not Encode Polyglutamine", "Autosomal Recessive Ataxia, Beauce Type", "Autosomal Recessive Ataxia Due to Ubiquinone Deficiency", "Autosomal Recessive Ataxia Due to PEX10 Deficiency", "Autosomal Recessive Degenerative and Progressive Cerebellar Ataxia", "Autosomal Recessive Congenital Cerebellar Ataxia Due to MGLUR1 Deficiency", "Autosomal Recessive Congenital Cerebellar Ataxia Due to GRID2 Deficiency", "Autosomal Recessive Congenital Cerebellar Ataxia", "Autosomal Recessive Cerebellar Ataxia-pyramidal Signs-nystagmus-oculomotor Apraxia Syndrome", "Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to WWOX Deficiency", "Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to TUD Deficiency", "Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to KIAA0226 Deficiency", "Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome", "Autosomal Recessive Cerebellar Ataxia With Late-onset Spasticity", "Autosomal Recessive Cerebellar Ataxia Due to STUB1 Deficiency", "Autosomal Recessive Cerebellar Ataxia Due to a DNA Repair Defect", "Autosomal Recessive Cerebellar Ataxia - Saccadic Intrusion", "Autosomal Recessive Cerebellar Ataxia - Psychomotor Retardation", "Autosomal Recessive Cerebellar Ataxia - Blindness - Deafness", "Autosomal Recessive Cerebellar Ataxia", "Autosomal Dominant Spinocerebellar Ataxia Due to a Polyglutamine Anomaly", "Autosomal Dominant Spinocerebellar Ataxia Due to a Point Mutation", "Autosomal Dominant Spinocerebellar Ataxia Due to a Channelopathy", "Autosomal Dominant Spastic Ataxia Type 1", "Autosomal Dominant Spastic Ataxia", "Autosomal Dominant Optic Atrophy", "Ataxia-telangiectasia Variant", "Ataxia-telangiectasia", "Autosomal Dominant Cerebellar Ataxia, Deafness and Narcolepsy", "Autosomal Dominant Cerebellar Ataxia Type 4", "Autosomal Dominant Cerebellar Ataxia Type 3", "Autosomal Dominant Cerebellar Ataxia Type 2", "Autosomal Dominant Cerebellar Ataxia Type 1", "Autosomal Dominant Cerebellar Ataxia", "Ataxia-telangiectasia-like Disorder", "Ataxia With Vitamin E Deficiency", "Ataxia With Dementia", "Ataxia - Oculomotor Apraxia Type 1", "Ataxia - Other", "Ataxia - Genetic Diagnosis - Unknown", "Acquired Ataxia", "Adult-onset Autosomal Recessive Cerebellar Ataxia", "Alcohol Related Ataxia", "Multiple Endocrine Neoplasia", "Multiple Endocrine Neoplasia Type II", "Multiple Endocrine Neoplasia Type 1", "Multiple Endocrine Neoplasia Type 2", "Multiple Endocrine Neoplasia, Type IV", "Multiple Endocrine Neoplasia, Type 3", "Multiple Endocrine Neoplasia (MEN) Syndrome", "Multiple Endocrine Neoplasia Type 2B", "Multiple Endocrine Neoplasia Type 2A", "Atypical Hemolytic Uremic Syndrome", "Atypical HUS", "Wiedemann-Steiner Syndrome", "Breast Implant-Associated Anaplastic Large Cell Lymphoma", "Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA)", "Hemophagocytic Lymphohistiocytosis", "Behcet's Disease", "Alagille Syndrome", "Inclusion Body Myopathy With Early-onset Paget Disease and Frontotemporal Dementia (IBMPFD)", "Lowe Syndrome", "Pitt Hopkins Syndrome", "1p36 Deletion Syndrome", "Jansen Type Metaphyseal Chondrodysplasia", "Cockayne Syndrome", "Chronic Recurrent Multifocal Osteomyelitis", "CRMO", "Malan Syndrome", "Hereditary Sensory and Autonomic Neuropathy Type Ie", "VCP Disease", "Hypnic Jerking", "Sleep Myoclonus", "Mollaret Meningitis", "Recurrent Viral Meningitis", "CRB1", "Leber Congenital Amaurosis", "Retinitis Pigmentosa", "Rare Retinal Disorder", "KCNMA1-Channelopathy", "Primary Biliary Cirrhosis", "ZMYND11", "Transient Global Amnesia", "Glycogen Storage Disease", "Alstrom Syndrome", "White Sutton Syndrome", "DNM1", "EIEE31", "Myhre Syndrome", "Recurrent Respiratory Papillomatosis", "Laryngeal Papillomatosis", "Tracheal Papillomatosis", "Refsum Disease", "Nicolaides Baraitser Syndrome", "Leukodystrophy", "Tango2", "Cauda Equina Syndrome", "Rare Gastrointestinal Disorders", "Achalasia-Addisonian Syndrome", "Achalasia Cardia", "Achalasia Icrocephaly Syndrome", "Anal Fistula", "Congenital Sucrase-Isomaltase Deficiency", "Eosinophilic Gastroenteritis", "Idiopathic Gastroparesis", "Hirschsprung Disease", "Rare Inflammatory Bowel Disease", "Intestinal Pseudo-Obstruction", "Scleroderma", "Short Bowel Syndrome", "Sacral Agenesis", "Sacral Agenesis Syndrome", "Caudal Regression", "Scheuermann Disease", "SMC1A Truncated Mutations (Causing Loss of Gene Function)", "Cystinosis", "Juvenile Nephropathic Cystinosis", "Nephropathic Cystinosis", "Kennedy Disease", "Spinal Bulbar Muscular Atrophy", "Warburg Micro Syndrome", "Mucolipidoses", "Mitochondrial Diseases", "Mitochondrial Aminoacyl-tRNA Synthetases", "Mt-aaRS Disorders", "Hypertrophic Olivary Degeneration", "Non-Ketotic Hyperglycinemia", "Fish Odor Syndrome", "Halitosis", "Isolated Congenital Asplenia", "Lambert Eaton (LEMS)", "Biliary Atresia", "STAG1 Gene Mutation", "Coffin Lowry Syndrome", "Borjeson-Forssman-Lehman Syndrome", "Blau Syndrome", "Arginase 1 Deficiency", "HSPB8 Myopathy", "Beta-Mannosidosis", "TBX4 Syndrome", "DHDDS Gene Mutations", "MAND-MBD5-Associated Neurodevelopmental Disorder", "Constitutional Mismatch Repair Deficiency (CMMRD)", "SPATA5 Disorder", "SPATA5L1 Related Disorder", "Acrodysostosis", "Multi-systematic Smooth Muscle Dysfunction Syndrome", "CRELD1 (Cysteine Rich With EGF Like Domains 1)", "GNB1 Syndrome", "Pyruvate Dehydrogenase Complex Deficiency Disease", "Beta Mannosidosis", "Kbg Syndrome", "Labrune Syndrome", "Metachromatic Leukodystrophy (MLD)", "Moyamoya Disease", "OPHN1 Syndrome", "Oculopharyngeal Muscular Dystrophy (OPMD)", "TUBB3 Mutation", "WOREE (WWOX-related Epileptic Encephalopathy", "SCAR12", "Skraban-Deardorff Syndrome", "Hereditary Myopathy With Early Respiratory Failure" ], "interventions": [], "intervention_types": [], "sponsor": "Sanford Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 20000, "start_date": "2010-07", "completion_date": "2100-12", "has_results": false, "last_update_posted_date": "2025-05-29", "last_synced_at": "2026-09-03T22:11:17.699Z", "location_count": 1, "location_summary": "Sioux Falls, South Dakota", "locations": [ { "city": "Sioux Falls", "state": "South Dakota" } ], "official_url": "https://clinicaltrials.gov/study/NCT01793168" }, { "nct_id": "NCT00014456", "title": "Combination Chemotherapy Plus Filgrastim in Treating Patients With Advanced Solid Tumors", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Bladder Cancer", "Breast Cancer", "Carcinoma of Unknown Primary", "Esophageal Cancer", "Gastric Cancer", "Head and Neck Cancer", "Lung Cancer", "Melanoma (Skin)", "Ovarian Cancer", "Pancreatic Cancer", "Prostate Cancer", "Sarcoma" ], "interventions": [ { "name": "filgrastim", "type": "BIOLOGICAL" }, { "name": "docetaxel", "type": "DRUG" }, { "name": "gemcitabine hydrochloride", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "Dartmouth-Hitchcock Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 35, "start_date": "2000-03", "completion_date": "2005-10", "has_results": false, "last_update_posted_date": "2013-08-28", "last_synced_at": "2026-09-03T22:11:17.699Z", "location_count": 1, "location_summary": "Lebanon, New Hampshire", "locations": [ { "city": "Lebanon", "state": "New Hampshire" } ], "official_url": "https://clinicaltrials.gov/study/NCT00014456" }, { "nct_id": "NCT04544098", "title": "Lutathera in People With Gastroenteropancreatic (GEP), Bronchial or Unknown Primary Neuroendocrine Tumors That Have Spread to the Liver", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Neuroendocrine Tumors", "Liver-Dominant Metastatic Pancreatic Neuroendocrine Tumors" ], "interventions": [ { "name": "177Lu-DOTATATE", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Memorial Sloan Kettering Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 10, "start_date": "2020-09-02", "completion_date": "2027-09", "has_results": false, "last_update_posted_date": "2026-05-07", "last_synced_at": "2026-09-03T22:11:17.699Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT04544098" }, { "nct_id": "NCT00499733", "title": "Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial Cancer", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Cancer" ], "interventions": [ { "name": "cyclophosphamide", "type": "DRUG" }, { "name": "Cryoablation", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "120 Years", "sex": "ALL", "summary": "18 Years to 120 Years" }, "enrollment_count": 19, "start_date": "2007-06", "completion_date": "2013-01-09", "has_results": false, "last_update_posted_date": "2019-01-18", "last_synced_at": "2026-09-03T22:11:17.699Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00499733" }, { "nct_id": "NCT00005860", "title": "Oxaliplatin With Or Without Floxuridine and Leucovorin in Treating Patients With Metastatic Cancer of the Peritoneum", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Cancer" ], "interventions": [ { "name": "floxuridine", "type": "DRUG" }, { "name": "leucovorin calcium", "type": "DRUG" }, { "name": "oxaliplatin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Memorial Sloan Kettering Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": null, "start_date": "2000-04", "completion_date": null, "has_results": false, "last_update_posted_date": "2011-04-26", "last_synced_at": "2026-09-03T22:11:17.699Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00005860" }, { "nct_id": "NCT02685631", "title": "Yttrium Y 90 Resin Microspheres Data Collection in Unresectable Liver Cancer: the RESIN Study", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Localized Non-Resectable Adult Liver Carcinoma" ], "interventions": [ { "name": "Yttrium-90 Resin Microspheres", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Vanderbilt-Ingram Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1653, "start_date": "2015-07", "completion_date": "2021-08-31", "has_results": false, "last_update_posted_date": "2021-09-05", "last_synced_at": "2026-09-03T22:11:17.699Z", "location_count": 42, "location_summary": "Birmingham, Alabama • Tucson, Arizona • Little Rock, Arkansas + 34 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02685631" } ] }