{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neoplasm+Recurrence%2C+Local&page=2", "query": { "condition": "Neoplasm Recurrence, Local", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neoplasm+Recurrence%2C+Local&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-05-22T03:07:01.016Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03410043", "title": "Osimertinib, Surgery, and Radiation Therapy in Treating Patients With Stage IIIB or IV Non-small Cell Lung Cancer With EGFR Mutations, NORTHSTAR Study", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Lung Non-Small Cell Carcinoma", "Recurrent Lung Non-Small Cell Carcinoma", "Stage IIIB Lung Cancer AJCC v8", "Stage IV Lung Cancer AJCC v8", "Stage IVA Lung Cancer AJCC v8", "Stage IVB Lung Cancer AJCC v8" ], "interventions": [ { "name": "Osimertinib", "type": "DRUG" }, { "name": "Radiation Therapy", "type": "RADIATION" }, { "name": "Therapeutic Conventional Surgery", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "RADIATION", "PROCEDURE" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 173, "start_date": "2018-01-17", "completion_date": "2027-04-01", "has_results": false, "last_update_posted_date": "2026-04-06", "last_synced_at": "2026-05-22T03:07:01.016Z", "location_count": 4, "location_summary": "San Francisco, California • Denver, Colorado • New York, New York + 1 more", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "New York", "state": "New York" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03410043" }, { "nct_id": "NCT01846520", "title": "Family Caregiver Palliative Care Intervention in Supporting Caregivers of Patients With Stage II-IV Gastrointestinal, Gynecologic, Urologic and Lung Cancers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Healthy Subject", "Localized Transitional Cell Cancer of the Renal Pelvis and Ureter", "Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter", "Psychosocial Effects of Cancer and Its Treatment", "Recurrent Bladder Cancer", "Recurrent Cervical Cancer", "Recurrent Colon Cancer", "Recurrent Gastric Cancer", "Recurrent Ovarian Epithelial Cancer", "Recurrent Ovarian Germ Cell Tumor", "Recurrent Pancreatic Cancer", "Recurrent Rectal Cancer", "Recurrent Renal Cell Cancer", "Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter", "Recurrent Urethral Cancer", "Recurrent Uterine Sarcoma", "Regional Transitional Cell Cancer of the Renal Pelvis and Ureter", "Stage II Bladder Cancer", "Stage II Renal Cell Cancer", "Stage II Urethral Cancer", "Stage IIA Cervical Cancer", "Stage IIA Colon Cancer", "Stage IIA Gastric Cancer", "Stage IIA Ovarian Epithelial Cancer", "Stage IIA Ovarian Germ Cell Tumor", "Stage IIA Pancreatic Cancer", "Stage IIA Rectal Cancer", "Stage IIA Uterine Sarcoma", "Stage IIB Cervical Cancer", "Stage IIB Colon Cancer", "Stage IIB Gastric Cancer", "Stage IIB Ovarian Epithelial Cancer", "Stage IIB Ovarian Germ Cell Tumor", "Stage IIB Pancreatic Cancer", "Stage IIB Rectal Cancer", "Stage IIB Uterine Sarcoma", "Stage IIC Colon Cancer", "Stage IIC Ovarian Epithelial Cancer", "Stage IIC Ovarian Germ Cell Tumor", "Stage IIC Rectal Cancer", "Stage III Bladder Cancer", "Stage III Pancreatic Cancer", "Stage III Renal Cell Cancer", "Stage III Urethral Cancer", "Stage IIIA Cervical Cancer", "Stage IIIA Colon Cancer", "Stage IIIA Gastric Cancer", "Stage IIIA Ovarian Epithelial Cancer", "Stage IIIA Ovarian Germ Cell Tumor", "Stage IIIA Rectal Cancer", "Stage IIIA Uterine Sarcoma", "Stage IIIB Cervical Cancer", "Stage IIIB Colon Cancer", "Stage IIIB Gastric Cancer", "Stage IIIB Ovarian Epithelial Cancer", "Stage IIIB Ovarian Germ Cell Tumor", "Stage IIIB Rectal Cancer", "Stage IIIB Uterine Sarcoma", "Stage IIIC Colon Cancer", "Stage IIIC Gastric Cancer", "Stage IIIC Ovarian Epithelial Cancer", "Stage IIIC Ovarian Germ Cell Tumor", "Stage IIIC Rectal Cancer", "Stage IIIC Uterine Sarcoma", "Stage IV Bladder Cancer", "Stage IV Gastric Cancer", "Stage IV Ovarian Epithelial Cancer", "Stage IV Ovarian Germ Cell Tumor", "Stage IV Pancreatic Cancer", "Stage IV Renal Cell Cancer", "Stage IV Urethral Cancer", "Stage IVA Cervical Cancer", "Stage IVA Colon Cancer", "Stage IVA Rectal Cancer", "Stage IVA Uterine Sarcoma", "Stage IVB Cervical Cancer", "Stage IVB Colon Cancer", "Stage IVB Rectal Cancer", "Stage IVB Uterine Sarcoma", "Ureter Cancer", "Stage IIA Lung Carcinoma", "Stage IIB Lung Carcinoma", "Stage IIIA Lung Carcinoma", "Stage IIIB Lung Carcinoma" ], "interventions": [ { "name": "educational intervention", "type": "OTHER" }, { "name": "telephone-based intervention", "type": "BEHAVIORAL" }, { "name": "quality-of-life assessment", "type": "PROCEDURE" }, { "name": "questionnaire administration", "type": "OTHER" } ], "intervention_types": [ "OTHER", "BEHAVIORAL", "PROCEDURE" ], "sponsor": "City of Hope Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 200, "start_date": "2013-10", "completion_date": "2019-05-23", "has_results": false, "last_update_posted_date": "2020-01-23", "last_synced_at": "2026-05-22T03:07:01.016Z", "location_count": 1, "location_summary": "Duarte, California", "locations": [ { "city": "Duarte", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01846520" }, { "nct_id": "NCT01792726", "title": "A Comparison of Intra-operative Radiotherapy Boost With External Beam Radiotherapy Boost in Early Breast Cancer.", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Early Breast Cancer" ], "interventions": [ { "name": "Boost to the tumour bed", "type": "RADIATION" } ], "intervention_types": [ "RADIATION" ], "sponsor": "University College, London", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "FEMALE", "summary": "Female only" }, "enrollment_count": 1796, "start_date": "2013-06", "completion_date": "2022-04", "has_results": false, "last_update_posted_date": "2019-07-12", "last_synced_at": "2026-05-22T03:07:01.016Z", "location_count": 8, "location_summary": "Los Angeles, California • Savannah, Georgia • Detroit, Michigan + 5 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Savannah", "state": "Georgia" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Saint Joseph", "state": "Michigan" }, { "city": "Dobbs Ferry", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01792726" }, { "nct_id": "NCT04899908", "title": "Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Brain Cancer", "Brain Metastases", "Melanoma", "Lung Cancer", "Breast Cancer", "HER2-positive Breast Cancer", "Colorectal Cancer", "Gastrointestinal Cancer", "SRS", "SRT", "Whole Brain Radiation", "Stereotactic Radiation", "AGuIX", "Nanoparticle", "Cystic", "Brain Tumor" ], "interventions": [ { "name": "Stereotactic Radiation", "type": "RADIATION" }, { "name": "AGuIX gadolinium-based nanoparticles", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "RADIATION", "DRUG", "OTHER" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 134, "start_date": "2021-09-15", "completion_date": "2029-05", "has_results": false, "last_update_posted_date": "2026-03-19", "last_synced_at": "2026-05-22T03:07:01.016Z", "location_count": 2, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04899908" }, { "nct_id": "NCT00669656", "title": "Herbal Therapy for Treatment of Recurrent Prostate Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Prostate Cancer" ], "interventions": [ { "name": "Prostate Health Cocktail", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Southern California", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "MALE", "summary": "18 Years and older · Male only" }, "enrollment_count": 43, "start_date": "2008-07-06", "completion_date": "2014-10-14", "has_results": false, "last_update_posted_date": "2017-04-20", "last_synced_at": "2026-05-22T03:07:01.016Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00669656" }, { "nct_id": "NCT00454363", "title": "Pazopanib Hydrochloride in Treating Patients With Advanced Neuroendocrine Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Gastrin-Producing Neuroendocrine Tumor", "Lung Carcinoid Tumor", "Metastatic Digestive System Neuroendocrine Tumor G1", "Multiple Endocrine Neoplasia Type 1", "Pancreatic Glucagonoma", "Pancreatic Insulinoma", "Pancreatic Polypeptide Tumor", "Recurrent Digestive System Neuroendocrine Tumor G1", "Recurrent Pancreatic Neuroendocrine Carcinoma", "Regional Digestive System Neuroendocrine Tumor G1", "Somatostatin-Producing Neuroendocrine Tumor" ], "interventions": [ { "name": "Laboratory Biomarker Analysis", "type": "OTHER" }, { "name": "Pazopanib Hydrochloride", "type": "DRUG" }, { "name": "Pharmacological Study", "type": "OTHER" } ], "intervention_types": [ "OTHER", "DRUG" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 52, "start_date": "2007-03", "completion_date": "2014-12", "has_results": true, "last_update_posted_date": "2020-04-03", "last_synced_at": "2026-05-22T03:07:01.016Z", "location_count": 3, "location_summary": "Boston, Massachusetts • Houston, Texas", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00454363" }, { "nct_id": "NCT00003926", "title": "Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Brain and Central Nervous System Tumors", "Childhood Germ Cell Tumor", "Chordoma", "Kidney Cancer", "Liver Cancer", "Neuroblastoma", "Ovarian Cancer", "Retinoblastoma", "Sarcoma" ], "interventions": [ { "name": "amifostine trihydrate", "type": "DRUG" }, { "name": "busulfan", "type": "DRUG" }, { "name": "filgrastim", "type": "DRUG" }, { "name": "melphalan", "type": "DRUG" }, { "name": "thiotepa", "type": "DRUG" }, { "name": "peripheral blood stem cell transplantation (PBSC)", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "Masonic Cancer Center, University of Minnesota", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": "45 Years", "sex": "ALL", "summary": "1 Year to 45 Years" }, "enrollment_count": 13, "start_date": "1998-11", "completion_date": "2003-08", "has_results": false, "last_update_posted_date": "2017-11-29", "last_synced_at": "2026-05-22T03:07:01.016Z", "location_count": 1, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT00003926" }, { "nct_id": "NCT02927964", "title": "TLR9 Agonist SD-101, Ibrutinib, and Radiation Therapy in Treating Patients With Relapsed or Refractory Grade 1-3A Follicular Lymphoma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Grade 1 Follicular Lymphoma", "Grade 2 Follicular Lymphoma", "Grade 3a Follicular Lymphoma", "Recurrent Follicular Lymphoma", "Refractory Follicular Lymphoma", "Mantle Cell Lymphoma", "Marginal Zone Lymphoma" ], "interventions": [ { "name": "Ibrutinib", "type": "DRUG" }, { "name": "Radiation Therapy", "type": "RADIATION" }, { "name": "TLR9 Agonist SD-101", "type": "DRUG" } ], "intervention_types": [ "DRUG", "RADIATION" ], "sponsor": "Robert Lowsky", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 21, "start_date": "2016-11-07", "completion_date": "2023-05-18", "has_results": true, "last_update_posted_date": "2024-10-16", "last_synced_at": "2026-05-22T03:07:01.016Z", "location_count": 1, "location_summary": "Palo Alto, California", "locations": [ { "city": "Palo Alto", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02927964" }, { "nct_id": "NCT03325634", "title": "Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Primary Ovarian or Uterine Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Recurrent Endometrial Serous Adenocarcinoma", "Recurrent Fallopian Tube Carcinoma", "Recurrent Ovarian Carcinoma", "Recurrent Primary Peritoneal Carcinoma" ], "interventions": [ { "name": "Laboratory Biomarker Analysis", "type": "OTHER" }, { "name": "Quality-of-Life Assessment", "type": "OTHER" }, { "name": "Questionnaire Administration", "type": "OTHER" }, { "name": "Stereotactic Body Radiation Therapy", "type": "RADIATION" } ], "intervention_types": [ "OTHER", "RADIATION" ], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 15, "start_date": "2017-10-27", "completion_date": "2025-10-20", "has_results": false, "last_update_posted_date": "2025-10-23", "last_synced_at": "2026-05-22T03:07:01.016Z", "location_count": 1, "location_summary": "Aurora, Colorado", "locations": [ { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT03325634" }, { "nct_id": "NCT00436696", "title": "Genetic Analysis Using Blood or Bone Marrow From Participants With Neuroblastoma or Noncancerous Conditions", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Localized Resectable Neuroblastoma", "Localized Unresectable Neuroblastoma", "Recurrent Neuroblastoma", "Regional Neuroblastoma", "Stage 4 Neuroblastoma" ], "interventions": [ { "name": "Laboratory Biomarker Analysis", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Children's Oncology Group", "sponsor_class": "NETWORK", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 9350, "start_date": "2006-12-11", "completion_date": null, "has_results": false, "last_update_posted_date": "2018-08-07", "last_synced_at": "2026-05-22T03:07:01.016Z", "location_count": 2, "location_summary": "Jackson, Mississippi • Philadelphia, Pennsylvania", "locations": [ { "city": "Jackson", "state": "Mississippi" }, { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00436696" } ] }