{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Nerve+Blocks&page=22",
    "query": {
      "condition": "Nerve Blocks",
      "page": 22
    },
    "page_size": 10
  },
  "pagination": {
    "page": 22,
    "page_size": 10,
    "total_count": 572,
    "total_pages": 58,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Nerve+Blocks&page=23&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Nerve+Blocks&page=21&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-25T15:28:18.211Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04157036",
      "title": "Evaluation of Methylprednisolone or Ibuprofen on Efficacy of Nerve Blocks With Symptomatic Irreversible Pulpitis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Irreversible Pulpitis"
      ],
      "interventions": [
        {
          "name": "Ibuprofen",
          "type": "DRUG"
        },
        {
          "name": "Methylprednisolone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Walter Reed National Military Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 3,
      "start_date": "2020-02-01",
      "completion_date": "2021-10-06",
      "has_results": false,
      "last_update_posted_date": "2022-08-29",
      "last_synced_at": "2026-10-25T15:28:18.211Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04157036"
    },
    {
      "nct_id": "NCT01495624",
      "title": "The Effect of Systemic or Perineural Dexamethasone on the Duration of Interscalene Nerve Blocks With Ropivacaine",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Duration of Interscalene Block"
      ],
      "interventions": [
        {
          "name": "ropivacaine plus dexamethasone anesthetic",
          "type": "OTHER"
        },
        {
          "name": "ropivacaine plus saline plus dexamethasone anesthetic",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 16,
      "start_date": "2011-12",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2016-01-27",
      "last_synced_at": "2026-10-25T15:28:18.211Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01495624"
    },
    {
      "nct_id": "NCT05391464",
      "title": "Nerve Block for Pain Control After Fracture Surgery",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Fractures",
        "Distal Radius Fracture"
      ],
      "interventions": [
        {
          "name": "Peripheral Nerve Block",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "MaineGeneral Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 160,
      "start_date": "2022-05-16",
      "completion_date": "2025-06-18",
      "has_results": false,
      "last_update_posted_date": "2022-05-26",
      "last_synced_at": "2026-10-25T15:28:18.211Z",
      "location_count": 1,
      "location_summary": "Augusta, Maine",
      "locations": [
        {
          "city": "Augusta",
          "state": "Maine"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05391464"
    },
    {
      "nct_id": "NCT02669407",
      "title": "Splanchnic Nerve Anesthesia in Heart Failure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "splanchnic nerve anesthesia with a local anesthetic",
          "type": "PROCEDURE"
        },
        {
          "name": "regional nerve block with a local anesthetic (Lidocaine)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 14,
      "start_date": "2017-01-01",
      "completion_date": "2018-10",
      "has_results": true,
      "last_update_posted_date": "2019-12-06",
      "last_synced_at": "2026-10-25T15:28:18.211Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02669407"
    },
    {
      "nct_id": "NCT05461092",
      "title": "Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Delirium",
        "Pain, Back",
        "Spinal Fusion",
        "Thoracolumbar Interfascial Plane Block"
      ],
      "interventions": [
        {
          "name": "Thoracolumbar Interfascial Plane (TLIP) Block of bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Blood Test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "3D CAM Delirium Severity Scoring",
          "type": "OTHER"
        },
        {
          "name": "Generalized Anxiety Disorder 7-item (GAD-7) scale",
          "type": "OTHER"
        },
        {
          "name": "Numerical Rating Score (NRS)",
          "type": "OTHER"
        },
        {
          "name": "PROMIS-Pain Interference",
          "type": "OTHER"
        },
        {
          "name": "Oswestry Disability Index (ODI)",
          "type": "OTHER"
        },
        {
          "name": "Saint Louis University Mental Status Examination (SLUMs)",
          "type": "OTHER"
        },
        {
          "name": "Delirium Rating Scale-Revised-98 (DRS)",
          "type": "OTHER"
        },
        {
          "name": "Telephone Interview for Cognitive Status - Modified (TICS-M)",
          "type": "OTHER"
        },
        {
          "name": "Opioid Equivalents measured by Morphine Milligram Equivalents (MME)",
          "type": "OTHER"
        },
        {
          "name": "Patient Health Questionnaire depression scale (PHQ-8)",
          "type": "OTHER"
        },
        {
          "name": "Pain Catastrophizing",
          "type": "OTHER"
        },
        {
          "name": "Fear Avoidance Beliefs Questionnaire (FABQ)",
          "type": "OTHER"
        },
        {
          "name": "Opioid Side Effects and Likeability Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Daily Pain Trajectory",
          "type": "OTHER"
        },
        {
          "name": "Tampa Scale of Kinesiophobia",
          "type": "OTHER"
        },
        {
          "name": "Quality of Recovery 15",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIAGNOSTIC_TEST",
        "OTHER"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2024-01-01",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-27",
      "last_synced_at": "2026-10-25T15:28:18.211Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05461092"
    },
    {
      "nct_id": "NCT02198235",
      "title": "Prolonged Popliteal Fossa Nerve Blockade (Prolonged Pop)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Postoperative Pain"
      ],
      "interventions": [
        {
          "name": "Dexamethasone",
          "type": "DRUG"
        },
        {
          "name": "Buprenorphine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Hospital for Special Surgery, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 90,
      "start_date": "2012-10",
      "completion_date": "2014-02",
      "has_results": true,
      "last_update_posted_date": "2017-06-15",
      "last_synced_at": "2026-10-25T15:28:18.211Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02198235"
    },
    {
      "nct_id": "NCT00574015",
      "title": "The Comparison of Supraperiosteal Nerve Block With Opiate Analgesia in Alleviating the Pain of Toothache",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Toothache"
      ],
      "interventions": [
        {
          "name": "hydrocodone/acetaminophen",
          "type": "DRUG"
        },
        {
          "name": "bupivacaine (supraperiosteal nerve block)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Albany Medical College",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 18,
      "start_date": "2007-12",
      "completion_date": "2013-01",
      "has_results": false,
      "last_update_posted_date": "2014-03-24",
      "last_synced_at": "2026-10-25T15:28:18.211Z",
      "location_count": 1,
      "location_summary": "Albany, New York",
      "locations": [
        {
          "city": "Albany",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00574015"
    },
    {
      "nct_id": "NCT05610969",
      "title": "Music vs Midazolam During Preop Nerve Block Placement - Part 2 Study On Anxiolytic Options Before Peripheral Nerve Blocks",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Peripheral Nerve Block",
        "Anxiety",
        "Preoperative Anxiety"
      ],
      "interventions": [
        {
          "name": "Music",
          "type": "OTHER"
        },
        {
          "name": "Midazolam",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2021-09-01",
      "completion_date": "2023-05-08",
      "has_results": true,
      "last_update_posted_date": "2025-05-14",
      "last_synced_at": "2026-10-25T15:28:18.211Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05610969"
    },
    {
      "nct_id": "NCT01452126",
      "title": "Minimum Effective Concentration of Ropivacaine for Brachial Plexus Block Via the Supraclavicular and Infraclavicular Approach, Femoral Nerve Block, Sciatic Nerve Block Via the Popliteal and Parasacral Approach",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Surgical Anesthesia"
      ],
      "interventions": [
        {
          "name": "Ropivacaine concentration",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of New Mexico",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 49,
      "start_date": "2011-06",
      "completion_date": "2011-09",
      "has_results": true,
      "last_update_posted_date": "2016-12-19",
      "last_synced_at": "2026-10-25T15:28:18.211Z",
      "location_count": 1,
      "location_summary": "Albuquerque, New Mexico",
      "locations": [
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01452126"
    },
    {
      "nct_id": "NCT02787226",
      "title": "Liposomal Bupivacaine Infiltration vs Continuous Perineural Ropivacaine Infusion for Post-operative Pain After Total Shoulder Arthroplasty",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Postoperative Pain",
        "Shoulder Arthritis"
      ],
      "interventions": [
        {
          "name": "Liposomal Bupivacaine Infiltration",
          "type": "DRUG"
        },
        {
          "name": "Continuous Perineural Ropivicaine Infusion",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Eric Shepard",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2014-08",
      "completion_date": "2017-05-31",
      "has_results": false,
      "last_update_posted_date": "2018-02-09",
      "last_synced_at": "2026-10-25T15:28:18.211Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02787226"
    }
  ]
}