{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neural+Tube+Defect&page=4",
    "query": {
      "condition": "Neural Tube Defect",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 96,
    "total_pages": 10,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neural+Tube+Defect&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neural+Tube+Defect&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-01T13:44:45.184Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03936322",
      "title": "Minimally Invasive Fetoscopic Regenerative Repair of Spina Bifida - A Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spina Bifida",
        "Myelomeningocele",
        "Neural Tube Defects"
      ],
      "interventions": [
        {
          "name": "Minimally invasive fetoscopic repair of MMC",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Rodrigo Ruano",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 3,
      "start_date": "2019-05-07",
      "completion_date": "2024-06-30",
      "has_results": true,
      "last_update_posted_date": "2025-02-24",
      "last_synced_at": "2026-11-01T13:44:45.184Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03936322"
    },
    {
      "nct_id": "NCT06945835",
      "title": "High Intensity Exercise and Improving Physical Activity Among People With Neurologic Dysfunction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cerebral Palsy (CP)",
        "Stroke",
        "Spinal Cord Injury",
        "Traumatic Brain Injury",
        "Charcot Marie Tooth Disease (CMT)",
        "Spina Bifida"
      ],
      "interventions": [
        {
          "name": "Participate in high intensity exercise of at least 20 minutes in 60 minutes session of RPE greater than 6.",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Hartford",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "8 Years to 99 Years"
      },
      "enrollment_count": 15,
      "start_date": "2025-02-24",
      "completion_date": "2025-05-27",
      "has_results": false,
      "last_update_posted_date": "2025-11-03",
      "last_synced_at": "2026-11-01T13:44:45.184Z",
      "location_count": 1,
      "location_summary": "West Hartford, Connecticut",
      "locations": [
        {
          "city": "West Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06945835"
    },
    {
      "nct_id": "NCT06929572",
      "title": "Autologous Human Umbilical Cord Tissue Patch for Postnatal Closure of Open Neural Tube Defects",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spina Bifida"
      ],
      "interventions": [
        {
          "name": "Autologous umbilical cord patch",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "24 Hours",
        "sex": "ALL",
        "summary": "Up to 24 Hours"
      },
      "enrollment_count": 15,
      "start_date": "2025-08-05",
      "completion_date": "2033-01",
      "has_results": false,
      "last_update_posted_date": "2026-09-24",
      "last_synced_at": "2026-11-01T13:44:45.184Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06929572"
    },
    {
      "nct_id": "NCT00866112",
      "title": "A Randomized Exercise Trial for Wheelchair Users",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injury",
        "Multiple Sclerosis",
        "Muscular Dystrophy",
        "Cerebral Palsy",
        "Spina Bifida",
        "Amputation",
        "Arthritis",
        "Stroke"
      ],
      "interventions": [
        {
          "name": "Educational session to promote physical activity",
          "type": "OTHER"
        },
        {
          "name": "Minimal contact",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Kansas",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 135,
      "start_date": "2008-05",
      "completion_date": "2012-06",
      "has_results": false,
      "last_update_posted_date": "2012-06-15",
      "last_synced_at": "2026-11-01T13:44:45.184Z",
      "location_count": 1,
      "location_summary": "Lawrence, Kansas",
      "locations": [
        {
          "city": "Lawrence",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00866112"
    },
    {
      "nct_id": "NCT02509377",
      "title": "Fetal Myelomeningocele Repair With Maternal BMI Between 35.0 and 40.0",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myelomeningocele",
        "Pregnancy"
      ],
      "interventions": [
        {
          "name": "Open Fetal Repair of Myelomeningocele",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "St. Louis University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 1,
      "start_date": "2015-07",
      "completion_date": "2017-05",
      "has_results": false,
      "last_update_posted_date": "2018-06-28",
      "last_synced_at": "2026-11-01T13:44:45.184Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02509377"
    },
    {
      "nct_id": "NCT01133288",
      "title": "Yulex Glove Prospective Study in Spina Bifida",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spina Bifida",
        "Latex Allergy"
      ],
      "interventions": [
        {
          "name": "Yulex gloves",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Hugo W. Moser Research Institute at Kennedy Krieger, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 7,
      "start_date": "2009-07",
      "completion_date": "2011-07",
      "has_results": true,
      "last_update_posted_date": "2011-12-23",
      "last_synced_at": "2026-11-01T13:44:45.184Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01133288"
    },
    {
      "nct_id": "NCT02592291",
      "title": "Mobile Health Self-Management and Support System for Chronic and Complex Health Conditions",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injuries",
        "Cerebral Palsy",
        "Spinal Dysraphism",
        "Brain Injuries",
        "Spina Bifida",
        "Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "MHealth",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 160,
      "start_date": "2019-10-01",
      "completion_date": "2026-09",
      "has_results": false,
      "last_update_posted_date": "2026-09-03",
      "last_synced_at": "2026-11-01T13:44:45.184Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02592291"
    },
    {
      "nct_id": "NCT00001327",
      "title": "Establishing the Physiology of Syringomyelia",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Arnold Chiari Deformity",
        "Hydrocephalus",
        "Syringomyelia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "1992-07-29",
      "completion_date": "2011-03-31",
      "has_results": false,
      "last_update_posted_date": "2017-07-02",
      "last_synced_at": "2026-11-01T13:44:45.184Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00001327"
    },
    {
      "nct_id": "NCT02230072",
      "title": "Fetoscopic Meningomyelocele Repair Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Neural Tube Defect"
      ],
      "interventions": [
        {
          "name": "fetoscopy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 64 Years · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2014-07-29",
      "completion_date": "2025-06-23",
      "has_results": false,
      "last_update_posted_date": "2026-06-29",
      "last_synced_at": "2026-11-01T13:44:45.184Z",
      "location_count": 2,
      "location_summary": "Stanford, California • Houston, Texas",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02230072"
    },
    {
      "nct_id": "NCT03856034",
      "title": "Laparotomy Versus Percutaneous Endoscopic Correction of Myelomeningocele",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neural Tube Defects",
        "Spina Bifida",
        "Myelomeningocele",
        "Chiari Malformation"
      ],
      "interventions": [
        {
          "name": "Fetoscopy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "USFetus",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 12,
      "start_date": "2018-11-02",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2019-11-13",
      "last_synced_at": "2026-11-01T13:44:45.184Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California • Wellington, Florida",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Wellington",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03856034"
    }
  ]
}