{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neural+Tube+Defects",
    "query": {
      "condition": "Neural Tube Defects"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 93,
    "total_pages": 10,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neural+Tube+Defects&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T04:12:48.391Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04087902",
      "title": "Long-Term Longitudinal QoL in Patients Undergoing EEA",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pituitary Tumor",
        "Meningioma",
        "Rathke Cleft Cysts",
        "Chordoma",
        "Chondrosarcoma",
        "Craniopharyngioma",
        "Encephalocele",
        "Esthesioneuroblastoma"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 400,
      "start_date": "2019-07-16",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-20",
      "last_synced_at": "2026-05-22T04:12:48.391Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04087902"
    },
    {
      "nct_id": "NCT05491525",
      "title": "A Study of Vibegron in Pediatric Participants 2 Years to Less Than (<) 18 Years of Age With NDO and on CIC",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Neurogenic Detrusor Overactivity"
      ],
      "interventions": [
        {
          "name": "Vibegron",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Urovant Sciences GmbH",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "2 Years to 17 Years"
      },
      "enrollment_count": 85,
      "start_date": "2022-10-12",
      "completion_date": "2027-09",
      "has_results": false,
      "last_update_posted_date": "2024-07-03",
      "last_synced_at": "2026-05-22T04:12:48.391Z",
      "location_count": 6,
      "location_summary": "Orange, California • Jacksonville, Florida • Wichita, Kansas + 3 more",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Wichita",
          "state": "Kansas"
        },
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "Albany",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05491525"
    },
    {
      "nct_id": "NCT04652908",
      "title": "Cellular Therapy for In Utero Repair of Myelomeningocele - The CuRe Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Myelomeningocele"
      ],
      "interventions": [
        {
          "name": "Placental Mesenchymal Stem Cells seeded on a commercially available dural graft extracellular matrix",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Untreated contemporaneous cohort",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Weeks",
        "maximum_age": "25 Weeks",
        "sex": "ALL",
        "summary": "19 Weeks to 25 Weeks"
      },
      "enrollment_count": 55,
      "start_date": "2021-06-21",
      "completion_date": "2027-03",
      "has_results": false,
      "last_update_posted_date": "2026-01-20",
      "last_synced_at": "2026-05-22T04:12:48.391Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04652908"
    },
    {
      "nct_id": "NCT00477932",
      "title": "Genes Mutation Pentalogy of Cantrell",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pentalogy of Cantrell",
        "Mutations in Non-muscle Genes"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Children's Healthcare of Atlanta",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "2 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2006-03",
      "completion_date": "2012-01",
      "has_results": false,
      "last_update_posted_date": "2014-12-17",
      "last_synced_at": "2026-05-22T04:12:48.391Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00477932"
    },
    {
      "nct_id": "NCT00951509",
      "title": "Virtual Reality Based Testing of Power Wheelchair Driving Skills",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Spinal Cord Injury",
        "Spina Bifida",
        "Spinal Cord Disease"
      ],
      "interventions": [
        {
          "name": "Power Mobility Road Test (PMRT)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "US Department of Veterans Affairs",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 31,
      "start_date": "2011-08",
      "completion_date": "2013-01",
      "has_results": true,
      "last_update_posted_date": "2015-08-24",
      "last_synced_at": "2026-05-22T04:12:48.391Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00951509"
    },
    {
      "nct_id": "NCT03936322",
      "title": "Minimally Invasive Fetoscopic Regenerative Repair of Spina Bifida - A Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spina Bifida",
        "Myelomeningocele",
        "Neural Tube Defects"
      ],
      "interventions": [
        {
          "name": "Minimally invasive fetoscopic repair of MMC",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Rodrigo Ruano",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 3,
      "start_date": "2019-05-07",
      "completion_date": "2024-06-30",
      "has_results": true,
      "last_update_posted_date": "2025-02-24",
      "last_synced_at": "2026-05-22T04:12:48.391Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03936322"
    },
    {
      "nct_id": "NCT05581472",
      "title": "Examining Different Components of Online Acceptance and Commitment Therapy for People With Chiari Malformation",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Pain",
        "Chiari Malformation"
      ],
      "interventions": [
        {
          "name": "Online Acceptance and Commitment Therapy Intervention + Phone Coaching",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Online Acceptance and Commitment Therapy Intervention without phone coaching",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Kent State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 113,
      "start_date": "2023-01-09",
      "completion_date": "2024-09",
      "has_results": false,
      "last_update_posted_date": "2023-06-15",
      "last_synced_at": "2026-05-22T04:12:48.391Z",
      "location_count": 1,
      "location_summary": "Kent, Ohio",
      "locations": [
        {
          "city": "Kent",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05581472"
    },
    {
      "nct_id": "NCT05672849",
      "title": "Safety and Efficacy of Devices Used in Fetoscopic Neural Tube Defect Repair Cases",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neural Tube Defects"
      ],
      "interventions": [
        {
          "name": "Modified Surgical Instruments/Devices (Sheaths and Irrigator)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Michael A Belfort",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 100,
      "start_date": "2022-11-14",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2025-12-15",
      "last_synced_at": "2026-05-22T04:12:48.391Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05672849"
    },
    {
      "nct_id": "NCT05587634",
      "title": "Virtual Peer Health Coaching for Adolescents With Disabilities",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cerebral Palsy",
        "Spina Bifida"
      ],
      "interventions": [
        {
          "name": "Virtual Peer Health Coaching",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Spaulding Rehabilitation Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "12 Years to 17 Years"
      },
      "enrollment_count": 25,
      "start_date": "2020-07-01",
      "completion_date": "2022-12-31",
      "has_results": false,
      "last_update_posted_date": "2022-10-25",
      "last_synced_at": "2026-05-22T04:12:48.391Z",
      "location_count": 1,
      "location_summary": "Charlestown, Massachusetts",
      "locations": [
        {
          "city": "Charlestown",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05587634"
    },
    {
      "nct_id": "NCT00394888",
      "title": "Hemangioma Associated With High Rates of Morbidity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hemangioma"
      ],
      "interventions": [
        {
          "name": "MRI",
          "type": "DEVICE"
        },
        {
          "name": "MRI of head and neck",
          "type": "DEVICE"
        },
        {
          "name": "Dermatological Examination",
          "type": "OTHER"
        },
        {
          "name": "Cardiac examination",
          "type": "OTHER"
        },
        {
          "name": "Abdominal ultrasound",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "Up to 18 Years"
      },
      "enrollment_count": 433,
      "start_date": "2005-11",
      "completion_date": "2010-01",
      "has_results": true,
      "last_update_posted_date": "2013-09-20",
      "last_synced_at": "2026-05-22T04:12:48.391Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00394888"
    }
  ]
}