{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neural+Tube+Defects+%28NTDs%29&page=2",
    "query": {
      "condition": "Neural Tube Defects (NTDs)",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neural+Tube+Defects+%28NTDs%29&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T16:44:16.596Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01961557",
      "title": "Evaluating a New Knee-Ankle-Foot Brace to Improve Gait in Children With Movement Disorders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Incomplete Spinal Cord Injury",
        "Muscular Dystrophy",
        "Spina Bifida",
        "Cerebral Palsy"
      ],
      "interventions": [
        {
          "name": "EA-KAFO",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "National Institutes of Health Clinical Center (CC)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "5 Years to 100 Years"
      },
      "enrollment_count": 24,
      "start_date": "2015-07-02",
      "completion_date": "2025-06-05",
      "has_results": false,
      "last_update_posted_date": "2026-06-30",
      "last_synced_at": "2026-07-23T16:44:16.596Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01961557"
    },
    {
      "nct_id": "NCT02669836",
      "title": "Posterior Fossa Decompression With or Without Duraplasty for Chiari Type I Malformation With Syringomyelia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arnold-Chiari Malformation, Type 1",
        "Chiari Malformation Type I",
        "Type I Arnold-Chiari Malformation",
        "Syringomyelia"
      ],
      "interventions": [
        {
          "name": "Posterior fossa decompression",
          "type": "PROCEDURE"
        },
        {
          "name": "Dural Augmentation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "Up to 21 Years"
      },
      "enrollment_count": 162,
      "start_date": "2016-04",
      "completion_date": "2020-07-31",
      "has_results": true,
      "last_update_posted_date": "2024-10-31",
      "last_synced_at": "2026-07-23T16:44:16.596Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02669836"
    },
    {
      "nct_id": "NCT00083499",
      "title": "Mutations in Genes Associated With Pentalogy of Cantrell",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pentalogy of Cantrell"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "Up to 100 Years"
      },
      "enrollment_count": 59,
      "start_date": "2004-09-15",
      "completion_date": "2019-09-06",
      "has_results": false,
      "last_update_posted_date": "2020-10-08",
      "last_synced_at": "2026-07-23T16:44:16.596Z",
      "location_count": 2,
      "location_summary": "Bethesda, Maryland • Houston, Texas",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00083499"
    },
    {
      "nct_id": "NCT02664207",
      "title": "Extended Criteria For Fetal Myelomeningocele Repair",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Myelomeningocele",
        "Pregnancy",
        "Diabetes Mellitus in Pregnancy",
        "Fetal Anomaly"
      ],
      "interventions": [
        {
          "name": "Open Fetal Repair of Myelomeningocele",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "16 Years to 45 Years · Female only"
      },
      "enrollment_count": 12,
      "start_date": "2016-01-26",
      "completion_date": "2023-12",
      "has_results": false,
      "last_update_posted_date": "2024-05-08",
      "last_synced_at": "2026-07-23T16:44:16.596Z",
      "location_count": 2,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02664207"
    },
    {
      "nct_id": "NCT00004738",
      "title": "Genetic Analysis of the Chiari I Malformation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Syringomyelia",
        "Type I Arnold Chiari Malformation"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "1 Year and older"
      },
      "enrollment_count": 152,
      "start_date": "2001-06-04",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2026-07-16",
      "last_synced_at": "2026-07-23T16:44:16.596Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00004738"
    },
    {
      "nct_id": "NCT02509377",
      "title": "Fetal Myelomeningocele Repair With Maternal BMI Between 35.0 and 40.0",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myelomeningocele",
        "Pregnancy"
      ],
      "interventions": [
        {
          "name": "Open Fetal Repair of Myelomeningocele",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "St. Louis University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 1,
      "start_date": "2015-07",
      "completion_date": "2017-05",
      "has_results": false,
      "last_update_posted_date": "2018-06-28",
      "last_synced_at": "2026-07-23T16:44:16.596Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02509377"
    },
    {
      "nct_id": "NCT04362592",
      "title": "In-Utero Endoscopic Correction of Spina Bifida",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neural Tube Defects",
        "Spina Bifida",
        "Myelomeningocele"
      ],
      "interventions": [
        {
          "name": "In Utero Endoscopic Correction of Myelomeningocele IDE - Percutaneous Technique",
          "type": "DEVICE"
        },
        {
          "name": "In Utero Endoscopic Correction of Myelomeningocele IDE - Laparotomy/Uterine Exteriorization Technique",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "52 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 52 Years · Female only"
      },
      "enrollment_count": 110,
      "start_date": "2018-11-02",
      "completion_date": "2031-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-04",
      "last_synced_at": "2026-07-23T16:44:16.596Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California • Wellington, Florida",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Wellington",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04362592"
    },
    {
      "nct_id": "NCT01667770",
      "title": "Dural Graft Equivalent Comparison Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chiari Malformation"
      ],
      "interventions": [
        {
          "name": "decompression of Chiari malformation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "St. Joseph's Hospital and Medical Center, Phoenix",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 41,
      "start_date": "2012-01-18",
      "completion_date": "2018-03-12",
      "has_results": false,
      "last_update_posted_date": "2021-06-15",
      "last_synced_at": "2026-07-23T16:44:16.596Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01667770"
    },
    {
      "nct_id": "NCT05562713",
      "title": "CIC Behavioral Economics in Children With Spina Bifida",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spina Bifida",
        "Neurogenic Bladder"
      ],
      "interventions": [
        {
          "name": "Present Bias without Loss Aversion",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Present Bias with Loss Aversion",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "4 Years to 12 Years"
      },
      "enrollment_count": 22,
      "start_date": "2023-08-01",
      "completion_date": "2024-04-18",
      "has_results": false,
      "last_update_posted_date": "2024-06-06",
      "last_synced_at": "2026-07-23T16:44:16.596Z",
      "location_count": 2,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05562713"
    },
    {
      "nct_id": "NCT01150708",
      "title": "A Prospective Natural History Study of Patients With Syringomyelia",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Syringomyelia",
        "Arnold Chiari Deformity"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 180,
      "start_date": "2010-08-03",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2026-06-16",
      "last_synced_at": "2026-07-23T16:44:16.596Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01150708"
    }
  ]
}