{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neurocognitive+Disease&page=2",
    "query": {
      "condition": "Neurocognitive Disease",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neurocognitive+Disease&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T11:20:03.101Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00991328",
      "title": "Role of Absolute Cerebral Oximetry to Prevent Neurocognitive Injury in Elderly Patients Undergoing Cardiac Surgery",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Post-Operative Delirium",
        "Postoperative Cognitive Dysfunction"
      ],
      "interventions": [
        {
          "name": "SctO2 < 60 %.",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2009-09",
      "completion_date": "2010-12",
      "has_results": false,
      "last_update_posted_date": "2016-09-16",
      "last_synced_at": "2026-07-24T11:20:03.101Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00991328"
    },
    {
      "nct_id": "NCT03634007",
      "title": "Gene Therapy for APOE4 Homozygote of Alzheimer's Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Alzheimer Disease",
        "Early Onset Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "LX1001",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Lexeo Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2019-11-06",
      "completion_date": "2024-11-07",
      "has_results": false,
      "last_update_posted_date": "2025-10-20",
      "last_synced_at": "2026-07-24T11:20:03.101Z",
      "location_count": 4,
      "location_summary": "Maitland, Florida • Orlando, Florida • New York, New York + 1 more",
      "locations": [
        {
          "city": "Maitland",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03634007"
    },
    {
      "nct_id": "NCT02675530",
      "title": "Parallel Effects of Schizophrenia and N-methyl-D-aspartate (NMDA) Antagonism",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Schizophrenia"
      ],
      "interventions": [
        {
          "name": "ketamine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "21 Years to 45 Years"
      },
      "enrollment_count": 33,
      "start_date": "2007-12",
      "completion_date": "2011-12",
      "has_results": false,
      "last_update_posted_date": "2016-02-05",
      "last_synced_at": "2026-07-24T11:20:03.101Z",
      "location_count": 1,
      "location_summary": "West Haven, Connecticut",
      "locations": [
        {
          "city": "West Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02675530"
    },
    {
      "nct_id": "NCT06234930",
      "title": "The Feasibility, Safety and Tolerability of VR-based Audiovisual Stimulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Aging",
        "Alzheimer's Disease"
      ],
      "interventions": [
        {
          "name": "Audiovisual stimulation VR system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Clarity Health Technologies, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "50 Years to 90 Years"
      },
      "enrollment_count": 27,
      "start_date": "2024-07-11",
      "completion_date": "2025-03-14",
      "has_results": false,
      "last_update_posted_date": "2025-09-02",
      "last_synced_at": "2026-07-24T11:20:03.101Z",
      "location_count": 2,
      "location_summary": "Portola Valley, California • Leesburg, Florida",
      "locations": [
        {
          "city": "Portola Valley",
          "state": "California"
        },
        {
          "city": "Leesburg",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06234930"
    },
    {
      "nct_id": "NCT03212300",
      "title": "TSA Exercise Prehabilitation in Older Adults",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postoperative Delirium and Delayed Functional Recovery"
      ],
      "interventions": [
        {
          "name": "Aerobic Exercise Training (AET)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "55 Years to 75 Years"
      },
      "enrollment_count": 3,
      "start_date": "2018-09-28",
      "completion_date": "2020-08-12",
      "has_results": false,
      "last_update_posted_date": "2020-08-14",
      "last_synced_at": "2026-07-24T11:20:03.101Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03212300"
    },
    {
      "nct_id": "NCT01993836",
      "title": "Markers of Alzheimers Disease and Cognitive Outcomes After Perioperative Care",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Alzheimers Disease",
        "Postoperative Delirium",
        "Post Operative Cognitive Dysfunction"
      ],
      "interventions": [
        {
          "name": "Total intravenous anesthesia with propofol",
          "type": "DRUG"
        },
        {
          "name": "General anesthesia with isoflurane",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 191,
      "start_date": "2013-11",
      "completion_date": "2019-01-10",
      "has_results": true,
      "last_update_posted_date": "2023-03-22",
      "last_synced_at": "2026-07-24T11:20:03.101Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01993836"
    },
    {
      "nct_id": "NCT02225314",
      "title": "Computer-based Cognitive Training for Individuals With Parkinson's Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson's Disease",
        "Mild Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "Brain Fitness",
          "type": "BEHAVIORAL"
        },
        {
          "name": "InSight",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Active Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "21 Years to 90 Years"
      },
      "enrollment_count": 25,
      "start_date": "2012-04",
      "completion_date": "2015-12",
      "has_results": false,
      "last_update_posted_date": "2016-01-08",
      "last_synced_at": "2026-07-24T11:20:03.101Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02225314"
    },
    {
      "nct_id": "NCT06218407",
      "title": "Development and Evaluation of Computerized Chemosensory Based Orbitofrontal Networks Training for Treatment of Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Chronic Pain",
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Computerized Chemosensory-Based Orbitofrontal Cortex Training (CBOT) short burst paradigm",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Computerized Chemosensory-Based Orbitofrontal Cortex Training (CBOT) long burst paradigm",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Computerized Chemosensory-Based Orbitofrontal Cortex Training plus beta caryophyllene (CBOT-Plus)",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Computerized Chemosensory-Based Orbitofrontal Cortex Training (CBOT)",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Evon Medics LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 86,
      "start_date": "2023-04-27",
      "completion_date": "2023-09-15",
      "has_results": false,
      "last_update_posted_date": "2024-01-23",
      "last_synced_at": "2026-07-24T11:20:03.101Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06218407"
    },
    {
      "nct_id": "NCT02769234",
      "title": "EEG/ERP Longitudinal Study in Alzheimer's Disease (AD)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer's Disease"
      ],
      "interventions": [
        {
          "name": "ERP/EEG test",
          "type": "PROCEDURE"
        },
        {
          "name": "Psychometric testing",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Neuronetrix, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "60 Years to 95 Years"
      },
      "enrollment_count": 75,
      "start_date": "2016-05",
      "completion_date": "2017-07",
      "has_results": false,
      "last_update_posted_date": "2020-02-26",
      "last_synced_at": "2026-07-24T11:20:03.101Z",
      "location_count": 3,
      "location_summary": "West Palm Beach, Florida • Brookline, Massachusetts • Bennington, Vermont",
      "locations": [
        {
          "city": "West Palm Beach",
          "state": "Florida"
        },
        {
          "city": "Brookline",
          "state": "Massachusetts"
        },
        {
          "city": "Bennington",
          "state": "Vermont"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02769234"
    },
    {
      "nct_id": "NCT02225106",
      "title": "Dopamine Receptor Imaging to Predict Response to Stimulant Therapy in Chronic TBI",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cognition Disorder",
        "Attention Deficit Disorder",
        "Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "Methylphenidate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 11,
      "start_date": "2014-08-06",
      "completion_date": "2017-06-21",
      "has_results": true,
      "last_update_posted_date": "2019-11-15",
      "last_synced_at": "2026-07-24T11:20:03.101Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02225106"
    }
  ]
}